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Information on SUBCLASS 3.3.2
Subclass Accession number: 4681
Subclass: 3.3.2 PSSM
Type: HH alpha-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 42

Average sequence ID (%) : 10.4 +/- 13.2
Average RMSD (Å) : 0.688 +/- 0.269

Consensus geometry
d (Å): 11 delta (°): 45-90 theta (°): 135-180 rho (°): 180-225
Consensus Sequence: XXXXpXp
(φψ)-conformation: aapapaa
Pattern: x[acgilmvwy]xxxx[dehknrsty]x[adegknqrst]xxx
Conservation:-0.374-0.499-0.195-0.5930.129-0.9662.707-0.4040.425-0.8320.905-0.302
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a3a_A_1251a3a   A130141RLAHTTSVDEVLHHHH---HHHHHaaaaxabaaaaa
1d5a_A_4481d5a   A466477KMKATVDPIERKHHHH---HHHHHaaaaxaxaaaaa
1dbh_A_3451dbh   A360371LEEKSEDQEDKEHHHH-S-HHHHHaaaapabaaaaa
1dkz_A_5591dkz   A574585TALKGEDKAAIEHHHTSS-HHHHHaaaabaxaaaaa
1dpe_*_4371dpe   -445456PARATDDHNKRVHHHH---HHHHHaaaaxaxaaaaa
1dqw_A_61dqw   A920RAATHPSPVAAKHHHH-S-HHHHHaaaapaxaaaaa
1dvp_A_841dvp   A93104FLESTPHENVRQHHHH-S-HHHHHaaaaxabaaaaa
1dys_A_1401dys   A143154NMVTGTSAFCRNHHHH--SHHHHHaaaaxaxaaaaa
1h6g_B_4131h6g   B437448ACSISNNEEGVKHHHT---HHHHHaaaaxaxaaaaa
1he1_A_1441he1   A155166IRAGSQVEESRIHHHH-S-HHHHHaaaaxabaaaaa
1hn0_A_3361hn0   A349360AYVLEKDPTQKAHHHH--SHHHHHaaaaxaxaaaaa
1hs6_A_5501hs6   A557568MATEQGRMKFTRHHHH---HHHHHaaaabaxaaaaa
1hu3_A_9121hu3   A916927KLLKNHDEESLEHHHHS-SHHHHHaaaaxaxaaaaa
1i1i_P_2221i1i   P228239VMKKCCVPETRRHHHH---HHHHHaaaapaxaaaaa
1j37_A_1481j37   A152163VISKSRDHEELAHHHH---HHHHHaaaapabaaaaa
1jdh_A_1921jdh   A201212TMQNTNDVETARHHHH---HHHHHaaaaxaxaaaaa
1jdh_A_3201jdh   A327338IMRTYTYEKLLWHHHH---HHHHHaaaaxaxaaaaa
1jkv_A_1371jkv   A158169LYSMTEDEGVRDHHTT---HHHHHaaaabaxaaaaa
1k40_A_9801k40   A10031014LAQQYVMTSLQQHHHH--SHHHHHaaaabapaaaaa
1kid_*_3391kid   -352363QIEEATSDYDREHHHH--SHHHHHaaaaxabaaaaa
1kkh_A_2181kkh   A231242EALKIKNKEDFGHHHH--SHHHHHaaaapabaaaaa
1kp8_A_3391kp8   A352363QIEEATSDYDREHHHS--SHHHHHaaaaxabaaaaa
1m0l_A_1051m0l   A124135VGALTKVYSYRFHHHH-SSHHHHHaaaaxaxaaaaa
1m5w_A_1571m5w   A158169CYADAKTDAEQAHHHH--SHHHHHaaaapabaaaaa
1mhy_B_1481mhy   B169180VGRDCLSDTIRQHHHH-SSHHHHHaaaaxabaaaaa
1mhy_B_2281mhy   B237248IWQGVQDWNEILHHHS---HHHHHaaaabapaaaaa
1o8a_A_1641o8a   A168179VMATSRKYEDLLHHHH---HHHHHaaaaxabaaaaa
1o9d_A_1141o9d   A114125LIPSAASGDSKVHHHH--SHHHHHaaaaxabaaaaa
1oaa_*_2051oaa   -210221ARETSKDPELRSHHHH-S-HHHHHaaaapaxaaaaa
1omr_A_1801omr   A183194LRLIQFEPQKVKHHHH---HHHHHaaaapaxaaaaa
1ovn_A_1651ovn   A178189KQEQLTDPEQQQHHHH--SHHHHHaaaaxaxaaaaa
1oxx_K_2251oxx   K228239LYDNPVSIQVASHHHS-SSHHHHHaaaaxabaaaaa
1oy3_D_2771oy3   D280291SALLRPNPILARHHHTSS-HHHHHaaaabapaaaaa
1qas_A_2481qas   A255266IERYEPSETAKAHHHH---HHHHHaaaaxaxaaaaa
1qkr_A_9441qkr   A968979VAKQCTDKRIRTHHHH---HHHHHaaaaxaxaaaaa
1qsa_A_2691qsa   A278289AIMRSQSTSLIEHHHT---HHHHHaaaaxaxaaaaa
1qv9_A_2061qv9   A220231GCFVEQDKERYVHHHT---HHHHHaaaaxaxaaaaa
1r2f_A_1291r2f   A140151AHYVSDEPLKKKHHHHSS-HHHHHaaaaxabaaaaa
1r42_A_1481r42   A151162IMANSLDYNERLHHHH---HHHHHaaaaxaxaaaaa
1tgo_A_4481tgo   A466477KMKATIDPIEKKHHHH---HHHHHaaaaxaxaaaaa
1uiu_A_4281uiu   A437448EVLATHDETQRQHHHH---HHHHHaaaaxaxaaaaa
256b_A_3256b   A1627VIEKADNAAQVKHHHH--SHHHHHaaaaxabaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1dbh_A_3451dbh   A     MSESELENOMETHIONINE P - 346
1dbh_A_3451dbh   A     MSESELENOMETHIONINE V - 347
1dbh_A_3451dbh   A     MSESELENOMETHIONINE C - 350
1dbh_A_3451dbh   A     MSESELENOMETHIONINE L - 351
1dbh_A_3451dbh   A     MSESELENOMETHIONINE F - 354
1dpe_*_4371dpe   *     CDCADMIUM ION H - 452
1dpe_*_4371dpe   *     CDCADMIUM ION V - 456
1dpe_*_4371dpe   *     CDCADMIUM ION E - 457
1dpe_*_4371dpe   *     CDCADMIUM ION H - 467
1dpe_*_4371dpe   *     CDCADMIUM ION D - 468
1h6g_B_4131h6g   B     MSESELENOMETHIONINE V - 447
1h6g_B_4131h6g   B     MSESELENOMETHIONINE K - 448
1h6g_B_4131h6g   B     CACALCIUM ION K - 448
1h6g_B_4131h6g   B     MSESELENOMETHIONINE L - 449
1h6g_B_4131h6g   B     CACALCIUM ION L - 449
1h6g_B_4131h6g   B     MSESELENOMETHIONINE V - 450
1h6g_B_4131h6g   B     CACALCIUM ION V - 450
1he1_A_1441he1   A     GDPGUANOSINE-5'-DIPHOSPHATE R - 146
1he1_A_1441he1   A     AF3ALUMINUM FLUORIDE R - 146
1he1_A_1441he1   A     MGMAGNESIUM ION R - 146
1he1_A_1441he1   A     AF3ALUMINUM FLUORIDE T - 150
1hs6_A_5501hs6   A     BES2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID R - 563
1hs6_A_5501hs6   A     BES2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID K - 565
1hu3_A_9121hu3   A     MSESELENOMETHIONINE D - 912
1hu3_A_9121hu3   A     MSESELENOMETHIONINE C - 913
1hu3_A_9121hu3   A     MSESELENOMETHIONINE V - 914
1hu3_A_9121hu3   A     MSESELENOMETHIONINE V - 915
1hu3_A_9121hu3   A     MSESELENOMETHIONINE L - 918
1hu3_A_9121hu3   A     MSESELENOMETHIONINE L - 926
1hu3_A_9121hu3   A     MSESELENOMETHIONINE E - 927
1hu3_A_9121hu3   A     MSESELENOMETHIONINE L - 929
1hu3_A_9121hu3   A     MSESELENOMETHIONINE C - 930
1hu3_A_9121hu3   A     MSESELENOMETHIONINE R - 931
1hu3_A_9121hu3   A     MSESELENOMETHIONINE L - 932
1hu3_A_9121hu3   A     MSESELENOMETHIONINE L - 933
1hu3_A_9121hu3   A     MSESELENOMETHIONINE I - 936
1hu3_A_9121hu3   A     MSESELENOMETHIONINE G - 937
1hu3_A_9121hu3   A     MSESELENOMETHIONINE L - 940
1jkv_A_1371jkv   A     EDO1,2-ETHANEDIOL M - 141
1jkv_A_1371jkv   A     EDO1,2-ETHANEDIOL R - 142
1jkv_A_1371jkv   A     EDO1,2-ETHANEDIOL F - 143
1jkv_A_1371jkv   A     EDO1,2-ETHANEDIOL V - 145
1jkv_A_1371jkv   A     EDO1,2-ETHANEDIOL V - 146
1jkv_A_1371jkv   A     OHHYDROXIDE ION R - 147
1jkv_A_1371jkv   A     AZIAZIDE ION R - 147
1jkv_A_1371jkv   A     MN3MANGANESE (III) ION R - 147
1jkv_A_1371jkv   A     OHHYDROXIDE ION E - 148
1jkv_A_1371jkv   A     AZIAZIDE ION E - 148
1jkv_A_1371jkv   A     MN3MANGANESE (III) ION E - 148
1jkv_A_1371jkv   A     EDO1,2-ETHANEDIOL S - 149
1jkv_A_1371jkv   A     OHHYDROXIDE ION A - 151
1jkv_A_1371jkv   A     AZIAZIDE ION A - 151
1jkv_A_1371jkv   A     OHHYDROXIDE ION V - 155
1jkv_A_1371jkv   A     AZIAZIDE ION V - 155
1jkv_A_1371jkv   A     OHHYDROXIDE ION L - 174
1jkv_A_1371jkv   A     AZIAZIDE ION L - 174
1jkv_A_1371jkv   A     MN3MANGANESE (III) ION L - 174
1jkv_A_1371jkv   A     OHHYDROXIDE ION L - 175
1jkv_A_1371jkv   A     AZIAZIDE ION L - 175
1jkv_A_1371jkv   A     OHHYDROXIDE ION R - 177
1jkv_A_1371jkv   A     AZIAZIDE ION R - 177
1jkv_A_1371jkv   A     MN3MANGANESE (III) ION R - 177
1jkv_A_1371jkv   A     OHHYDROXIDE ION E - 178
1jkv_A_1371jkv   A     AZIAZIDE ION E - 178
1jkv_A_1371jkv   A     MN3MANGANESE (III) ION E - 178
1jkv_A_1371jkv   A     OHHYDROXIDE ION H - 181
1jkv_A_1371jkv   A     MN3MANGANESE (III) ION H - 181
1jkv_A_1371jkv   A     MN3MANGANESE (III) ION F - 185
1jkv_A_1371jkv   A     EDO1,2-ETHANEDIOL M - 186
1jkv_A_1371jkv   A     EDO1,2-ETHANEDIOL Q - 189
1jkv_A_1371jkv   A     EDO1,2-ETHANEDIOL E - 193
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL I - 108
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL V - 112
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL G - 116
1m0l_A_1051m0l   A     RETRETINAL M - 118
1m0l_A_1051m0l   A     RETRETINAL I - 119
1m0l_A_1051m0l   A     RETRETINAL T - 121
1m0l_A_1051m0l   A     RETRETINAL G - 122
1m0l_A_1051m0l   A     RETRETINAL L - 123
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL Y - 131
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL S - 132
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL Y - 133
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL F - 135
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL V - 136
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL W - 137
1m0l_A_1051m0l   A     RETRETINAL W - 137
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL W - 138
1m0l_A_1051m0l   A     RETRETINAL W - 138
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL A - 139
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL I - 140
1m0l_A_1051m0l   A     RETRETINAL S - 141
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL T - 142
1m0l_A_1051m0l   A     RETRETINAL T - 142
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL A - 143
1m0l_A_1051m0l   A     RETRETINAL A - 143
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL M - 145
1m0l_A_1051m0l   A     RETRETINAL M - 145
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL L - 146
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL F - 153
1m0l_A_1051m0l   A     LI11-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL F - 154
1o8a_A_1641o8a   A     NAGN-ACETYL-D-GLUCOSAMINE W - 180
1o9d_A_1141o9d   A     TPOPHOSPHOTHREONINE D - 133
1o9d_A_1141o9d   A     TPOPHOSPHOTHREONINE R - 136
1o9d_A_1141o9d   A     TPOPHOSPHOTHREONINE Y - 137
1o9d_A_1141o9d   A     TPOPHOSPHOTHREONINE E - 140
1oaa_*_2051oaa   *     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE D - 205
1oaa_*_2051oaa   *     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE M - 206
1oaa_*_2051oaa   *     OAAOXALOACETATE ION M - 206
1oaa_*_2051oaa   *     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Q - 207
1oaa_*_2051oaa   *     OAAOXALOACETATE ION Q - 207
1oaa_*_2051oaa   *     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Q - 208
1oaa_*_2051oaa   *     OAAOXALOACETATE ION Q - 208
1oaa_*_2051oaa   *     OAAOXALOACETATE ION A - 210
1oaa_*_2051oaa   *     OAAOXALOACETATE ION R - 211
1oaa_*_2051oaa   *     OAAOXALOACETATE ION L - 223
1oxx_K_2251oxx   K     IODIODIDE ION P - 225
1oxx_K_2251oxx   K     IODIODIDE ION E - 226
1oxx_K_2251oxx   K     IODIODIDE ION D - 227
1oxx_K_2251oxx   K     IODIODIDE ION N - 231
1oxx_K_2251oxx   K     IODIODIDE ION V - 233
1oxx_K_2251oxx   K     IODIODIDE ION S - 234
1oxx_K_2251oxx   K     IODIODIDE ION I - 235
1oxx_K_2251oxx   K     IODIODIDE ION Q - 236
1oxx_K_2251oxx   K     IODIODIDE ION V - 237
1qkr_A_9441qkr   A     MSESELENOMETHIONINE L - 947
1qkr_A_9441qkr   A     MSESELENOMETHIONINE C - 950
1qkr_A_9441qkr   A     MSESELENOMETHIONINE A - 951
1qkr_A_9441qkr   A     MSESELENOMETHIONINE D - 953
1qkr_A_9441qkr   A     MSESELENOMETHIONINE I - 954
1qkr_A_9441qkr   A     MSESELENOMETHIONINE A - 957
1qkr_A_9441qkr   A     MSESELENOMETHIONINE S - 958
1qkr_A_9441qkr   A     MSESELENOMETHIONINE V - 961
1qv9_A_2061qv9   A     MSESELENOMETHIONINE A - 206
1qv9_A_2061qv9   A     MSESELENOMETHIONINE L - 207
1qv9_A_2061qv9   A     MSESELENOMETHIONINE E - 208
1qv9_A_2061qv9   A     MSESELENOMETHIONINE I - 209
1qv9_A_2061qv9   A     MSESELENOMETHIONINE A - 210
1qv9_A_2061qv9   A     MSESELENOMETHIONINE E - 211
1qv9_A_2061qv9   A     MSESELENOMETHIONINE N - 212
1qv9_A_2061qv9   A     MSESELENOMETHIONINE V - 213
1qv9_A_2061qv9   A     MSESELENOMETHIONINE A - 214
1qv9_A_2061qv9   A     MSESELENOMETHIONINE V - 216
1qv9_A_2061qv9   A     MSESELENOMETHIONINE S - 217
1qv9_A_2061qv9   A     MSESELENOMETHIONINE V - 218
1qv9_A_2061qv9   A     MSESELENOMETHIONINE C - 221
1qv9_A_2061qv9   A     MSESELENOMETHIONINE F - 222
1qv9_A_2061qv9   A     MSESELENOMETHIONINE A - 235
1qv9_A_2061qv9   A     MSESELENOMETHIONINE S - 236
1qv9_A_2061qv9   A     MSESELENOMETHIONINE A - 237
1qv9_A_2061qv9   A     MSESELENOMETHIONINE H - 238
1r2f_A_1291r2f   A     FEFE (III) ION E - 158
256b_A_3256b   A     HEMPROTOPORPHYRIN IX CONTAINING FE L - 3
256b_A_3256b   A     HEMPROTOPORPHYRIN IX CONTAINING FE E - 4
256b_A_3256b   A     HEMPROTOPORPHYRIN IX CONTAINING FE D - 5
256b_A_3256b   A     HEMPROTOPORPHYRIN IX CONTAINING FE N - 6
256b_A_3256b   A     HEMPROTOPORPHYRIN IX CONTAINING FE M - 7
256b_A_3256b   A     HEMPROTOPORPHYRIN IX CONTAINING FE E - 8
256b_A_3256b   A     HEMPROTOPORPHYRIN IX CONTAINING FE T - 9
256b_A_3256b   A     HEMPROTOPORPHYRIN IX CONTAINING FE L - 10
256b_A_3256b   A     HEMPROTOPORPHYRIN IX CONTAINING FE N - 11
256b_A_3256b   A     HEMPROTOPORPHYRIN IX CONTAINING FE L - 14
256b_A_3256b   A     HEMPROTOPORPHYRIN IX CONTAINING FE M - 33
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1he1_A_1441he1   A AC1GDP BINDING SITE FOR CHAIN CR - 146
1o8a_A_1641o8a   A CL1CL BINDING SITE FOR CHAIN AR - 186

Clusters included in this Subclass
CLUSTER: HH.2.106
CLUSTER: HH.2.38
CLUSTER: HH.3.27
CLUSTER: HH.4.27
CLUSTER: HH.4.68