ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.4.3

Subclass Accession number: 4785
Subclass: 4.4.3

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
GO : GO:0003955 (>75 %) GO:0016651 (>75 %)
SCOP : 52171 (>75 %) 52218 (>75 %) 52235 (>75 %)

Number of loops: 5

Average sequence ID (%) : 24.8 +/- 30.3
Average RMSD (Å) : 0.640 +/- 0.134

Consensus geometry

d (Å): 13

delta (°): 90-135

theta (°): 45-90

rho (°): 180-225

Consensus Sequence:	XpGphXXX
(φψ)-conformation:	aalappaa

Pattern:	[ey]	[EGNP]	x	[DEK]	x	x	[ael]	[AER]	[LTY]	[KL]	[EKQ]	[GR]	[HKNRS]	[GL]	[ADPS]	[aps]	[AD]	[HIL]	[ATV]	[ADER]	[eq]	x	[AKL]	[AKT]	x	x	[AES]
Conservation:	-0.231	-0.603	-0.363	1.689	-0.886	-1.388	-1.126	-0.036	0.145	0.163	2.065	2.284	0.124	-0.627	-0.348	-0.511	1.885	-0.100	0.739	-0.491	0.064	-0.619	-0.466	0.129	-0.436	-1.663	0.607

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1brw_A_250	1brw	A	251	277	LEVKEAIETLKGNGPHDLTELCLTLGS	HHHHHHHHHHTT-S-HHHHHHHHHHHH	aaaaaaaaaaavaxxaaaaaaaaaaaa
1d4a_A_67	1d4a	A	67	93	YPAESVLAYKEGHLSPDIVAEQKKLEA	HHHHHHHHHHHT-B-HHHHHHHHHHHH	aaaaaaaaaaavaxpaaaaaaaaaaaa
1khd_A_279	1khd	A	281	307	ENRDILARLLQGKGDAAHARQVAANVA	HHHHHHHHHHTT-S-HHHHHHHHHHHH	aaaaaaaaaaavaxxaaaaaaaaaaaa
1qr2_A_67	1qr2	A	67	93	YGVETHEAYKQRSLASDITDEQKKVRE	HHHHHHHHHHTT-B-HHHHHHHHHHHH	aaaaaaaaaaalaxxaaaaaaaaaaaa
1qrd_A_67	1qrd	A	67	93	YPVESSLAYKEGRLSPDIVAEQKKLEA	HHHHHHHHHHHT-B-HHHHHHHHHHHH	aaaaaaaaaaavaxpaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1brw_A_250	1brw	A	CACALCIUM ION	E - 252
1brw_A_250	1brw	A	CACALCIUM ION	E - 255
1brw_A_250	1brw	A	CACALCIUM ION	L - 268
1d4a_A_67	1d4a	A	FADFLAVIN-ADENINE DINUCLEOTIDE	Y - 67
1d4a_A_67	1d4a	A	FADFLAVIN-ADENINE DINUCLEOTIDE	P - 68
1qr2_A_67	1qr2	A	FADFLAVIN-ADENINE DINUCLEOTIDE	G - 68
1qr2_A_67	1qr2	A	FADFLAVIN-ADENINE DINUCLEOTIDE	T - 71

Clusters included in this Subclass