ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.45.1

Subclass Accession number: 4856
Subclass: 4.45.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 1.1 (>75 %)  1.1.1 (>75 %)  1.1.1.27
GO : GO:0004457 (>75 %)  GO:0004459 (>75 %)  GO:0016614 (>75 %)  GO:0016616 (>75 %)
SCOP : 56326 (>75 %)  56327 (>75 %)  56328 (>75 %)

Number of loops: 3

Average sequence ID (%) : 45.9 +/- 16.5
Average RMSD (Å) : 0.233 +/- 0.058

Consensus geometry

d (Å): 15

delta (°): 90-135

theta (°): 135-180

rho (°): 45-90

Consensus Sequence:	XKGhTphh
(φψ)-conformation:	aagbbNaa

Pattern:	[EK]	[AER]	[IV]	[FH]	[KV]	x	[V]	x	[DE]	[AS]	[A]	[Y]	[EQ]	[IV]	[I]	[EK]	[KL]	[K]	[G]	[AY]	[T]	[NSY]	[WY]	[AG]	[I]	[AG]	[LM]	[GS]	[LV]	[A]	[DR]	[LV]	[AIT]	[ER]	[AS]	[IM]	[LM]
Conservation:	-0.023	-1.317	0.309	0.048	-1.175	-1.468	0.646	-1.572	0.653	-0.365	0.646	2.684	0.314	0.309	0.646	-0.023	-1.235	1.325	2.004	-0.772	1.325	-1.241	1.804	-0.420	0.646	-0.300	0.113	-0.420	-0.365	0.646	-0.833	-0.365	-1.392	-0.360	-0.365	-0.209	0.107

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1i0z_A_228	1i0z	A	228	264	KEVHKMVVESAYEVIKLKGYTNWAIGLSVADLIESML	HHHHHHHHHHHHHHHHHHSS--HHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaaavbbNaaaaaaaaaaaaaaa
1ldn_A_222	1ldn	A	227	263	ERIFVNVRDAAYQIIEKKGATYYGIAMGLARVTRAIL	HHHHHHHHHHHHHHHHHHS---HHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaaavbxNaaaaaaaaaaaaaaa
9ldt_A_226	9ldt	A	226	262	KAVHKEVVDSAYEVIKLKGYTSWAIGLSVADLAESIM	HHHHHHHHHHHHHHHHHHSS--HHHHHHHHHHHHHHH	aaaaaaaaaaaaaaaaaagbbNaaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1i0z_A_228	1i0z	A	OXMOXAMIC ACID	S - 237
1i0z_A_228	1i0z	A	OXMOXAMIC ACID	A - 238
1i0z_A_228	1i0z	A	OXMOXAMIC ACID	I - 242
1i0z_A_228	1i0z	A	NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	Y - 247
1i0z_A_228	1i0z	A	NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	T - 248
1i0z_A_228	1i0z	A	OXMOXAMIC ACID	T - 248
1i0z_A_228	1i0z	A	NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	N - 249
1i0z_A_228	1i0z	A	NAI1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	I - 252
1i0z_A_228	1i0z	A	OXMOXAMIC ACID	I - 252
1ldn_A_222	1ldn	A	OXMOXAMIC ACID	A - 236
1ldn_A_222	1ldn	A	OXMOXAMIC ACID	A - 237
1ldn_A_222	1ldn	A	OXMOXAMIC ACID	I - 240
1ldn_A_222	1ldn	A	OXMOXAMIC ACID	I - 241
1ldn_A_222	1ldn	A	OXMOXAMIC ACID	A - 246
1ldn_A_222	1ldn	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	A - 246
1ldn_A_222	1ldn	A	OXMOXAMIC ACID	T - 247
1ldn_A_222	1ldn	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	T - 247
1ldn_A_222	1ldn	A	OXMOXAMIC ACID	Y - 248
1ldn_A_222	1ldn	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	Y - 248
1ldn_A_222	1ldn	A	OXMOXAMIC ACID	I - 251
1ldn_A_222	1ldn	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	I - 251
9ldt_A_226	9ldt	A	OXMOXAMIC ACID	S - 235
9ldt_A_226	9ldt	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	Y - 245
9ldt_A_226	9ldt	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	T - 246
9ldt_A_226	9ldt	A	OXMOXAMIC ACID	T - 246
9ldt_A_226	9ldt	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	S - 247
9ldt_A_226	9ldt	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	I - 250
9ldt_A_226	9ldt	A	OXMOXAMIC ACID	I - 250

Clusters included in this Subclass