ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 10.22.1

Subclass Accession number: 5119
Subclass: 10.22.1

Type: HH alpha-alpha
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
GO : GO:0004364 (>50 %) GO:0016765 (>50 %)
SCOP : 47615 (>75 %) 47616 (>75 %) 47617 (>75 %) 52832 (>75 %) 52833 (>75 %) 52862 (>75 %)

Number of loops: 3

Average sequence ID (%) : 77.2 +/- -38.3
Average RMSD (Å) : 0.467 +/- 0.252

Consensus geometry

d (Å): 19

delta (°): 90-135

theta (°): 135-180

rho (°): 270-315

Consensus Sequence:	pYhKDDpLYPKDPp
(φψ)-conformation:	aapabaaabpapaa

Pattern:	[S]	[RY]	[A]	[I]	x	[ILT]	[Y]	[L]	[AV]	[E]	[KT]	[Y]	[AG]	[K]	[D]	[D]	[KT]	[L]	[Y]	[P]	[K]	[D]	[P]	[KQ]	[KV]	[R]	[AS]	[V]	[V]	[N]	[Q]	[R]	[L]	[FY]	[F]	[D]	[IM]	[G]
Conservation:	-0.201	-1.313	-0.201	-0.201	-2.032	-1.605	1.447	-0.201	-1.299	0.348	-1.299	1.447	-1.010	0.348	0.897	0.897	-1.299	-0.201	1.447	1.447	0.348	0.897	1.447	-0.750	-1.703	0.348	-1.025	-0.201	-0.201	0.897	0.348	0.348	-0.201	0.219	0.897	0.897	-0.880	0.897

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1jlv_A_65	1jlv	A	65	102	SRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMG	HHHHHHHHHHHH---GGGS--SHHHHHHHHHHHHHHHH	aaaaaaaaaaaaxabaaabpapaaaaaaaaaaaaaaaa
1pn9_A_65	1pn9	A	65	102	SRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMG	HHHHHHHHHHHH---TTSS--SHHHHHHHHHHHHHHHH	aaaaaaaaaaaaxabaaabpapaaaaaaaaaaaaaaaa
1v2a_A_64	1v2a	A	64	101	SYAIVLYLVETYAKDDTLYPKDPKVRSVVNQRLFFDIG	HHHHHHHHHHHH-SSSTTS---HHHHHHHHHHHHHHHH	aaaaaaaaaaaaxabaaabpapaaaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1jlv_A_65	1jlv	A	GSHGLUTHATHIONE	S - 65
1jlv_A_65	1jlv	A	GSHGLUTHATHIONE	R - 66
1jlv_A_65	1jlv	A	GSHGLUTHATHIONE	Y - 98
1jlv_A_65	1jlv	A	GSHGLUTHATHIONE	M - 101
1jlv_A_65	1jlv	A	GSHGLUTHATHIONE	G - 102
1pn9_A_65	1pn9	A	GTXS-HEXYLGLUTATHIONE	S - 65
1pn9_A_65	1pn9	A	GTXS-HEXYLGLUTATHIONE	R - 66
1pn9_A_65	1pn9	A	GTXS-HEXYLGLUTATHIONE	Y - 98
1pn9_A_65	1pn9	A	GTXS-HEXYLGLUTATHIONE	M - 101
1pn9_A_65	1pn9	A	GTXS-HEXYLGLUTATHIONE	G - 102
1v2a_A_64	1v2a	A	GTSGLUTATHIONE SULFONIC ACID	S - 64
1v2a_A_64	1v2a	A	GTSGLUTATHIONE SULFONIC ACID	Y - 65
1v2a_A_64	1v2a	A	GTSGLUTATHIONE SULFONIC ACID	I - 67
1v2a_A_64	1v2a	A	GTSGLUTATHIONE SULFONIC ACID	F - 97
1v2a_A_64	1v2a	A	GTSGLUTATHIONE SULFONIC ACID	I - 100

Clusters included in this Subclass

CLUSTER: HH.9.102