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Information on SUBCLASS 12.3.1
Subclass Accession number: 5138
Subclass: 12.3.1 PSSM
Type: HH alpha-alpha
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : - (>75 %)  3.1 (>75 %)  3.1.1 (>75 %)  3.1.1.73.2 (>75 %)  3.2.2 (>75 %)  3.2.2.23
GO : GO:0003906 (>75 %)  GO:0004091 (>75 %)  GO:0004104 (>75 %)  GO:0004518 (>75 %)  GO:0004519 (>75 %)  GO:0004536 (>75 %)  GO:0008270 (>75 %)  GO:0008534 (>75 %)  GO:0016788 (>75 %)  GO:0016788 (>75 %)  GO:0016789 (>75 %)  GO:0016798 (>75 %)  GO:0016799 (>75 %)  GO:0016829 (>75 %)  GO:0016835 (>75 %)  GO:0019104 (>75 %)  GO:0046914 (>75 %)  
SCOP : 46946 (>75 %)  53473 (>75 %)  53474 (>75 %)  53475 (>75 %)  81297 (>75 %)  81626 (>75 %)  
 Number of loops: 4

Average sequence ID (%) : 33.7 +/- 23.2
Average RMSD (Å) : 0.625 +/- 0.320

Consensus geometry
d (Å): 13 delta (°): 45-90 theta (°): 90-135 rho (°): 315-360
Consensus Sequence: phGhphcpXAppLpXX
(φψ)-conformation: aalbpaappaaappaa
Pattern: [N][IY][LY]x[DSV][E]x[L][FW][AQR][AV][GR][IL]x[GP]x[HR]x[A][AKRS][DS][L][NST]x[AEK][EQ][ACIL][DER]x[L]x[EHR]x[ILM]x[AE][ITV][ILP]x[EFR][AS][IVY][AEM]
Conservation:2.7580.0400.728-0.897-0.9352.060-0.7381.3611.594-0.3830.1150.3710.667-1.2140.574-1.1710.738-0.9191.361-0.6470.2731.3610.054-1.214-0.5731.125-0.690-0.033-0.9541.361-0.584-0.044-0.7370.423-1.171-0.1740.010-0.788-1.476-1.0100.321-0.060-0.887
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1ee8_A_1611ee8   A161203NIYADEALFRARLSPFRPARSLTEEEARRLYRALREVLAEAVEHHHHHHHHHHTT--SSSBGGG--HHHHHHHHHHHHHHHHHHHHaaaaaaaaaaalbxaaxpaaaxxaaaaaaaaaaaaaaaaaaaa
1k3x_A_1681k3x   A168210NYLRVEILWQVGLTGNHKAKDLNAAQLDALAHALLEIPRFSYAHHHHHHHHHHHT--SS--GGGS-HHHHHHHHHHHHHHHHHHHHaaaaaaaaaaavbxaabbaaaxxaaaaaaaaaaaaaaaaaaaa
1k82_A_1681k82   A168210NIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEHHHHHHHHHHHT--TTSBGGG--HHHHHHHHHHHHHHHHHHHHaaaaaaaaaaavbpaappaaaxxaaaaaaaaaaaaaaaaaaaa
1r2z_A_1741r2z   A174216NIYVDESLFRAGILPGRPAASLSSKEIERLHEEMVATIGEAVMHHHHHHHHHHHT--TTSBGGG--HHHHHHHHHHHHHHHHHHHHaaaaaaaaaaavbxaaxpaaaxxaaaaaaaaaaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1ee8_A_1611ee8   A     ZNZINC ION F - 169
1k3x_A_1681k3x   A     PEDPENTANE-3,4-DIOL-5-PHOSPHATE N - 168
1k3x_A_1681k3x   A     PEDPENTANE-3,4-DIOL-5-PHOSPHATE Y - 169
1k3x_A_1681k3x   A     ZNZINC ION W - 176
1k3x_A_1681k3x   A     GOLGLYCEROL D - 195
1k3x_A_1681k3x   A     GOLGLYCEROL A - 196
1k3x_A_1681k3x   A     GOLGLYCEROL H - 199
1k3x_A_1681k3x   A     GOLGLYCEROL E - 203
1k82_A_1681k82   A     PEDPENTANE-3,4-DIOL-5-PHOSPHATE I - 169
1k82_A_1681k82   A     ZNZINC ION F - 176
1r2z_A_1741r2z   A     DHU5,6-DIHYDROURIDINE-5'-PHOSPHATE N - 174
1r2z_A_1741r2z   A     DHU5,6-DIHYDROURIDINE-5'-PHOSPHATE I - 175
1r2z_A_1741r2z   A     DHU5,6-DIHYDROURIDINE-5'-PHOSPHATE Y - 176
1r2z_A_1741r2z   A     ZNZINC ION F - 182

Clusters included in this Subclass
CLUSTER: HH.11.60
CLUSTER: HH.12.26