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Information on SUBCLASS 2.2.3
Subclass Accession number: 5349
Subclass: 2.2.3 PSSM
Type: HE alpha-beta
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 41

Average sequence ID (%) : 12.4 +/- 19.3
Average RMSD (Å) : 0.710 +/- 0.197

Consensus geometry
d (Å): 9 delta (°): 0-45 theta (°): 90-135 rho (°): 90-135
Consensus Sequence: XXXpXh
(φψ)-conformation: aapabb
Pattern: [adegkrs]x[afilmvwy]xxx[deknrst]x[afilmvy]xx
Conservation:-0.209-0.9150.511-0.475-0.660-0.3362.435-1.0710.973-0.004-0.249
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1ag9_A_411ag9   A4252EDLEAYDILLLHHHHT-SEEEEaaaaababbbb
1b9m_A_1931b9m   A194204AVAQNADNQLPHHHHTSSEEEEaaaaaxabbbx
1brm_A_601brm   A6171EALKALDIIVTHHHHT-SEEEEaaaaaxabbbb
1bz7_A_1831bz7   A184194ADYEKHKVYACHHHHT-S-EEEaaaaabaxbbb
1cjc_A_2591cjc   A263273ARRASASRAWGHHHHT-SEEEEaaaaaxabbbb
1dci_A_1731dci   A176186DLISACDIRYCHHHTTSSEEEEaaaaaxabbbb
1ei9_A_2131ei9   A217227KNLMALKKFVMHHHHTSSEEEEaaaaaxabbbb
1ey3_A_1411ey3   A144154ELAMMCDIIYAHHHHHSSEEEEaaaaaxabbbb
1f8r_A_2171f8r   A225235DIFAYEKRFDEHHHTT---EEEaaaaaxabbbb
1fsf_A_1901fsf   A191201GTLLDAEEVMIHHHHTSS-EEEaaaaaxabbbb
1gz0_A_2041gz0   A205215LTREHCDELISHHHHT-SEEEEaaaaaxabbbb
1h6u_A_721h6u   A7382ADLDGITTLS.HHHHT--EEE.aaaaaxabbb.
1hnu_A_1251hnu   A129139ALVALCDIVYSHHHHTSSEEEEaaaaaxabbbb
1ii2_A_711ii2   A8393EFLDTREHLFVHHHHTSSEEEEaaaaaxabbbb
1jj7_A_7031jj7   A704714SLVEQADHILFHHHHT-SEEEEaaaaaxabbbx
1kp8_A_4971kp8   A512522GLMITTECMVTHHHHT--EEEEaaaaaxabbbb
1ks9_A_581ks9   A5969DFLATSDLLLVHHHHT-SEEEEaaaaaxabbbb
1l3k_A_1561l3k   A160170DKIVIQKYHTVHHHHH-S--EEaaaaaxabbbb
1lgv_A_1871lgv   A188198EQWKSHRSYSCHHHHTSS-EEEaaaaababbbb
1lk3_L_1821lk3   L183193ADYESHNLYTCHHHHT--EEEEaaaaabaxbbb
1m2k_A_31m2k   A717KTIAESKYLVAHHHHT-SSEEEaaaaaxabxbb
1mam_L_1831mam   L184194DEYERHNSYTCHHHHT---EEEaaaaabaxbbb
1mfb_L_1851mfb   L186196RAWERHSSYSCHHHHT-SEEEEaaaaababbbb
1mju_L_1831mju   L184194DEYERHNSYTCHHHHT--EEEEaaaaabaxbbb
1ml4_A_2161ml4   A217227DVIGKLDVLYVHHHTT-SEEEEaaaaaxabbxx
1mr3_F_761mr3   F8090HYYRNTEGVIFHHHHT-SEEEEaaaaaxabbbb
1n0x_L_1831n0x   L184194ADYEKHKVYACHHHHT--EEEEaaaaabaxbbb
1n7m_H_1831n7m   H184194ADYEKHKVYACHHHHH--EEEEaaaaabaxbbb
1nij_A_1431nij   A147157SQVGYADRILLHHHHT-SEEEEaaaaaxabxbx
1nzy_A_1141nzy   A117127GISLASDMAICHHHHHSSEEEEaaaaaxabbbb
1pno_A_2971pno   A302312FIMKNASKVIIHHHHT-SEEEEaaaaaxabbbx
1pvd_A_2701pvd   A274284EAVESADLILSHHHHT-SEEEEaaaaaxabbbb
1q3q_A_4981q3q   A513523IMILRIDDVIAHHHHT--EEEEaaaaaxabbbb
1rz7_L_1831rz7   L184194ADYEKHKLYACHHHHT--EEEEaaaaabaxbbb
1s2d_A_1291s2d   A130138MIAQGVTTI..HHHHH-SEE..aaaaaxabb..
1tet_L_1841tet   L184194DEYEWHNSYTCHHHHT--EEEEaaaaababbbx
1uqt_A_1691uqt   A174184EQLCDYDLLGFHHHTTSSEEEEaaaaaxabbbb
2uag_A_592uag   A6070EWLMAADLIVAHHHHT-SEEEEaaaaaxabbbx
2up1_A_1562up1   A160170DKIVIQKYHTVHHHHTSS--EEaaaaaxabbbb
7fab_L_1787fab   L179189EQWKSHKSYSCHHHHT-S-EEEaaaaababbbx
8fab_A_1828fab   A183193EQWKSHRSYSCHHHHT-S-EEEaaaaababbbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1b9m_A_1931b9m   A     MSESELENOMETHIONINE L - 203
1b9m_A_1931b9m   A     MSESELENOMETHIONINE P - 204
1b9m_A_1931b9m   A     MSESELENOMETHIONINE G - 205
1b9m_A_1931b9m   A     MSESELENOMETHIONINE I - 206
1dci_A_1731dci   A     EDO1,2-ETHANEDIOL A - 180
1dci_A_1731dci   A     EDO1,2-ETHANEDIOL C - 181
1dci_A_1731dci   A     EDO1,2-ETHANEDIOL D - 182
1dci_A_1731dci   A     EDO1,2-ETHANEDIOL I - 183
1dci_A_1731dci   A     EDO1,2-ETHANEDIOL R - 184
1ei9_A_2131ei9   A     NAGN-ACETYL-D-GLUCOSAMINE E - 213
1ei9_A_2131ei9   A     NAGN-ACETYL-D-GLUCOSAMINE S - 214
1ei9_A_2131ei9   A     NAGN-ACETYL-D-GLUCOSAMINE Y - 215
1ei9_A_2131ei9   A     NAGN-ACETYL-D-GLUCOSAMINE N - 218
1ey3_A_1411ey3   A     DAK4-(N,N-DIMETHYLAMINO)CINNAMOYL-COA G - 141
1ey3_A_1411ey3   A     DAK4-(N,N-DIMETHYLAMINO)CINNAMOYL-COA G - 142
1ey3_A_1411ey3   A     DAK4-(N,N-DIMETHYLAMINO)CINNAMOYL-COA E - 144
1f8r_A_2171f8r   A     CITCITRIC ACID H - 223
1f8r_A_2171f8r   A     CITCITRIC ACID F - 227
1gz0_A_2041gz0   A     MSESELENOMETHIONINE R - 204
1gz0_A_2041gz0   A     MSESELENOMETHIONINE L - 205
1gz0_A_2041gz0   A     MSESELENOMETHIONINE T - 206
1gz0_A_2041gz0   A     MSESELENOMETHIONINE R - 207
1gz0_A_2041gz0   A     MSESELENOMETHIONINE H - 209
1gz0_A_2041gz0   A     MSESELENOMETHIONINE C - 210
1gz0_A_2041gz0   A     MSESELENOMETHIONINE D - 211
1gz0_A_2041gz0   A     MSESELENOMETHIONINE E - 212
1gz0_A_2041gz0   A     MSESELENOMETHIONINE L - 213
1gz0_A_2041gz0   A     MSESELENOMETHIONINE I - 214
1hnu_A_1251hnu   A     REOPERRHENATE G - 125
1hnu_A_1251hnu   A     REOPERRHENATE L - 126
1hnu_A_1251hnu   A     REOPERRHENATE S - 127
1hnu_A_1251hnu   A     EDO1,2-ETHANEDIOL A - 132
1hnu_A_1251hnu   A     EDO1,2-ETHANEDIOL L - 133
1hnu_A_1251hnu   A     EDO1,2-ETHANEDIOL C - 134
1hnu_A_1251hnu   A     REOPERRHENATE D - 135
1hnu_A_1251hnu   A     EDO1,2-ETHANEDIOL D - 135
1jj7_A_7031jj7   A     ADPADENOSINE-5'-DIPHOSPHATE L - 715
1kp8_A_4971kp8   A     ATPADENOSINE-5'-TRIPHOSPHATE V - 499
1m2k_A_31m2k   A     APRADENOSINE-5-DIPHOSPHORIBOSE T - 19
1mr3_F_761mr3   F     EGLETHYLENE GLYCOL L - 77
1mr3_F_761mr3   F     CRYPROPANE-1,2,3-TRIOL W - 78
1mr3_F_761mr3   F     EGLETHYLENE GLYCOL W - 78
1mr3_F_761mr3   F     PDO1,3-PROPANDIOL W - 78
1mr3_F_761mr3   F     EGLETHYLENE GLYCOL R - 79
1mr3_F_761mr3   F     EGLETHYLENE GLYCOL H - 80
1mr3_F_761mr3   F     EGLETHYLENE GLYCOL Y - 81
1mr3_F_761mr3   F     CRYPROPANE-1,2,3-TRIOL Y - 82
1mr3_F_761mr3   F     EGLETHYLENE GLYCOL Y - 82
1mr3_F_761mr3   F     CRYPROPANE-1,2,3-TRIOL R - 83
1mr3_F_761mr3   F     CRYPROPANE-1,2,3-TRIOL N - 84
1mr3_F_761mr3   F     EGLETHYLENE GLYCOL N - 84
1mr3_F_761mr3   F     CRYPROPANE-1,2,3-TRIOL T - 85
1mr3_F_761mr3   F     EGLETHYLENE GLYCOL T - 85
1mr3_F_761mr3   F     EGLETHYLENE GLYCOL E - 86
1mr3_F_761mr3   F     EGLETHYLENE GLYCOL G - 87
1mr3_F_761mr3   F     G3DGUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE V - 91
1mr3_F_761mr3   F     EOHETHANOL I - 92
1mr3_F_761mr3   F     G3DGUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE D - 93
1mr3_F_761mr3   F     EGLETHYLENE GLYCOL D - 93
1mr3_F_761mr3   F     EOHETHANOL D - 93
1nzy_A_1141nzy   A     CACALCIUM ION G - 114
1nzy_A_1141nzy   A     BCA4-HYDROXYBENZOYL COENZYME A G - 114
1nzy_A_1141nzy   A     CACALCIUM ION G - 115
1nzy_A_1141nzy   A     BCA4-HYDROXYBENZOYL COENZYME A G - 115
1pno_A_2971pno   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE P - 314
1q3q_A_4981q3q   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER V - 500
1q3q_A_4981q3q   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER K - 501

Clusters included in this Subclass
CLUSTER: HE.2.121
CLUSTER: HE.2.24
CLUSTER: HE.2.43
CLUSTER: HE.3.123
CLUSTER: HE.3.227
CLUSTER: HE.3.40
CLUSTER: HE.3.72
CLUSTER: HE.4.158
CLUSTER: HE.4.41
CLUSTER: HE.4.43
CLUSTER: HE.5.104