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| Information on SUBCLASS 2.2.12 |
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Subclass Accession number: 5358
Subclass: 2.2.12 
Type: HE alpha-beta DB: ArchDB95 Image coordinates: 
 Consensus coordinates:
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Number of loops: 5 Average sequence ID (%) : 21.5 +/- 19.1 Average RMSD (Å) : 0.660 +/- 0.297 Consensus geometry
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| Consensus Sequence: | PXhcLX |
| (φψ)-conformation: | aapabb |
| Pattern: | [AITV] | x | [EKQR] | x | [EKRT] | [LVY] | [AFLTV] | [HP] | x | [AFV] | [DKS] | [IL] | x |
| Conservation: | -0.141 | -0.564 | 0.648 | -1.130 | -0.067 | 0.179 | -0.919 | 2.017 | -1.208 | -0.428 | 0.564 | 1.643 | -0.595 |
| Loops included in this Subclass |
| Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
| 1jxh_A_119 | 1jxh | A | 124 | 136 | TLRVRLLPQVSLI | HHHHHTGGG-SEE | aaaaaaaaaxabb |
| 1kgd_A_865 | 1kgd | A | 876 | 888 | ILQRTYAHYFDLT | HHHHHHGGG-SEE | aaaaaaaaaxabb |
| 1lhp_A_133 | 1lhp | A | 135 | 147 | VYREKVVPVADII | HHHHTTGGG-SEE | aaaaaaaaaxabb |
| 1m1n_A_259 | 1m1n | A | 259 | 271 | ISEIELTPKVKLN | HHHHHHGGG-SEE | aaaaaaaaaxabb |
| 1ub0_A_117 | 1ub0 | A | 122 | 134 | ALKERLFPLADLV | HHHHHTGGG-SEE | aaaaaaaaaxabb |
| PDB ligands within a cut-off distance of 6 Å in this subclass |
| Loop | PDB | Chain | Ligands | Residue |
| 1kgd_A_865 | 1kgd | A | FMTFORMIC ACID | S - 866 |
| 1kgd_A_865 | 1kgd | A | FMTFORMIC ACID | L - 867 |
| 1kgd_A_865 | 1kgd | A | FMTFORMIC ACID | L - 870 |
| 1ub0_A_117 | 1ub0 | A | GOLGLYCEROL | D - 132 |
| Clusters included in this Subclass |
| CLUSTER: HE.5.377 |
| CLUSTER: HE.6.133 |
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