Logo
Information on SUBCLASS 2.4.7
Subclass Accession number: 5393
Subclass: 2.4.7 PSSM
Type: HE alpha-beta
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 1.6 (>75 %)  1.6.1 (>75 %)  1.6.1.2
GO : GO:0008746 (>75 %)  GO:0016651 (>75 %)  GO:0016652 (>75 %)  
SCOP : 52466 (>75 %)  52467 (>75 %)  52484 (>75 %)  
 Number of loops: 6

Average sequence ID (%) : 8.0 +/- 10.0
Average RMSD (Å) : 0.750 +/- 0.187

Consensus geometry
d (Å): 9 delta (°): 45-90 theta (°): 45-90 rho (°): 135-180
Consensus Sequence: Xpchhp
(φψ)-conformation: aalabb
Pattern: [cgpy][AFIKLV][filty]x[AKNQRS][DGR][glmy][givy][dkq]x
Conservation:-0.925-0.1390.530-1.0430.5972.200-0.758-0.2790.576-0.759
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a28_A_9071a28   A918927PKILAGMVKPHHHHTT-EEEaaaaavabbx
1b37_A_2681b37   A269278GVLQSDLIQFHHHHTTSSEEaaaaavabxb
1bt3_A_811bt3   A8998CAYCNGGYDQHHHHTT--EEaaaaavabbx
1gx1_A_1381gx1   A138147GFTGRGEGIAHHHHTTSEEEeaaaavabbb
1l1e_A_2561l1e   A271280KLFRQGYTDVHHHHTTS-EEaaaaavabbb
1rv1_A_501rv1   A6068YIMTKRLYD.HHHHTT-EE.aaaaalaxx.
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1a28_A_9071a28   A     STRPROGESTERONE M - 909
1b37_A_2681b37   A     FADFLAVIN-ADENINE DINUCLEOTIDE V - 270
1b37_A_2681b37   A     FADFLAVIN-ADENINE DINUCLEOTIDE L - 275
1b37_A_2681b37   A     FADFLAVIN-ADENINE DINUCLEOTIDE I - 276
1bt3_A_811bt3   A     C2OCU-O-CU LINKAGE H - 88
1bt3_A_811bt3   A     C2OCU-O-CU LINKAGE C - 92
1gx1_A_1381gx1   A     MSESELENOMETHIONINE I - 146
1gx1_A_1381gx1   A     MSESELENOMETHIONINE L - 153
1gx1_A_1381gx1   A     MSESELENOMETHIONINE L - 154
1gx1_A_1381gx1   A     MSESELENOMETHIONINE I - 155
1l1e_A_2561l1e   A     CO3CARBONATE ION V - 280
1rv1_A_501rv1   A     IMZCIS-[4,5-BIS-(4-BROMOPHENYL)-2-(2-ETHOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL]-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]METHANONE M - 50
1rv1_A_501rv1   A     IMZCIS-[4,5-BIS-(4-BROMOPHENYL)-2-(2-ETHOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL]-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]METHANONE K - 51
1rv1_A_501rv1   A     IMZCIS-[4,5-BIS-(4-BROMOPHENYL)-2-(2-ETHOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL]-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]METHANONE V - 53
1rv1_A_501rv1   A     IMZCIS-[4,5-BIS-(4-BROMOPHENYL)-2-(2-ETHOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL]-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]METHANONE L - 54
1rv1_A_501rv1   A     IMZCIS-[4,5-BIS-(4-BROMOPHENYL)-2-(2-ETHOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL]-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]METHANONE F - 55
1rv1_A_501rv1   A     IMZCIS-[4,5-BIS-(4-BROMOPHENYL)-2-(2-ETHOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL]-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]METHANONE L - 57
1rv1_A_501rv1   A     IMZCIS-[4,5-BIS-(4-BROMOPHENYL)-2-(2-ETHOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL]-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]METHANONE G - 58
1rv1_A_501rv1   A     IMZCIS-[4,5-BIS-(4-BROMOPHENYL)-2-(2-ETHOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL]-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]METHANONE Q - 59
1rv1_A_501rv1   A     IMZCIS-[4,5-BIS-(4-BROMOPHENYL)-2-(2-ETHOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL]-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]METHANONE I - 61
1rv1_A_501rv1   A     IMZCIS-[4,5-BIS-(4-BROMOPHENYL)-2-(2-ETHOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL]-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]METHANONE M - 62
1rv1_A_501rv1   A     IMZCIS-[4,5-BIS-(4-BROMOPHENYL)-2-(2-ETHOXY-4-METHOXYPHENYL)-4,5-DIHYDROIMIDAZOL-1-YL]-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]METHANONE Y - 67
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1bt3_A_811bt3   A CUABINDING SITE FOR COPPER AH - 88
1gx1_A_1381gx1   A SO4SO4 BINDING SITE FOR CHAIN BG - 138
1gx1_A_1381gx1   A SO4SO4 BINDING SITE FOR CHAIN BR - 142

Clusters included in this Subclass
CLUSTER: HE.3.145
CLUSTER: HE.4.192