Information on SUBCLASS 2.12.1 |
Subclass Accession number: 5448
Subclass: 2.12.1 Type: HE alpha-beta DB: ArchDB95 Image coordinates: Consensus coordinates: Conserved Annotation EC : 3.2 (>75 %) 3.2.2 (>75 %) 3.2.2.22 (>75 %) GO : GO:0016798 (>75 %) GO:0016799 (>75 %) GO:0030597 (>75 %) SCOP : 56370 (>75 %) 56371 (>75 %) 56372 (>75 %) |
Number of loops: 5 Average sequence ID (%) : 14.4 +/- 16.7 Average RMSD (Å) : 0.480 +/- 0.110 Consensus geometry
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Consensus Sequence: | phpGpp |
(φψ)-conformation: | aaplbb |
Pattern: | [aelm] | [DEK] | [deky] | [FITV] | [EKRS] | [GY] | x | [EKSW] | [gil] |
Conservation: | -0.690 | 1.262 | -1.174 | -0.045 | 0.519 | 1.698 | 0.010 | -0.513 | -1.065 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1hd2_A_25 | 1hd2 | A | 26 | 34 | AELFKGKKG | HHHTTTSEE | aaaaxvbbb |
1hs6_A_400 | 1hs6 | A | 411 | 419 | VEKFSYKSI | HHHHTTEEE | aaaapvbbb |
1j54_A_79 | 1j54 | A | 87 | 95 | MDYIRGAEL | HHHHTTSEE | aaaapvxxx |
1n8j_A_25 | 1n8j | A | 25 | 33 | EKDTEGRWS | HHHHTTSEE | aaaaxvbxb |
2aps_A_130 | 2aps | A | 130 | 138 | LDEVKGHSL | HHHHTTEEE | aaaaxvbbb |
PDB ligands within a cut-off distance of 6 Å in this subclass |
Loop | PDB | Chain | Ligands | Residue |
1j54_A_79 | 1j54 | A | EGLETHYLENE GLYCOL | G - 92 |
1j54_A_79 | 1j54 | A | EGLETHYLENE GLYCOL | A - 93 |
1j54_A_79 | 1j54 | A | MNMANGANESE (II) ION | I - 97 |
2aps_A_130 | 2aps | A | CUCOPPER (II) ION | M - 139 |
2aps_A_130 | 2aps | A | CUCOPPER (II) ION | I - 140 |
2aps_A_130 | 2aps | A | CUCOPPER (II) ION | H - 141 |
PDB Site Annotated loops in this subclass |
Loop | PDB | Chain | Site | Residue |
2aps_A_130 | 2aps | A | ACTCOPPER AND ZINC ARE LIGATED BY THREE CONSERVED HISTIDINES EACH IN THE ACTIVE SITE OF EACH SUBUNIT. | H - 141 |
Clusters included in this Subclass |
CLUSTER: HE.2.111 |
CLUSTER: HE.3.270 |