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Information on SUBCLASS 3.18.2
Subclass Accession number: 5558
Subclass: 3.18.2 PSSM
Type: HE alpha-beta
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
GO : GO:0003677 (>75 %)  GO:0003700 (>75 %)  GO:0003707 (>75 %)  GO:0004872 (>75 %)  GO:0004879 (>75 %)  GO:0005496 (>75 %)  
SCOP : 48507 (>75 %)  48508 (>75 %)  48509 (>75 %)  
 Number of loops: 4

Average sequence ID (%) : 34.4 +/- 25.4
Average RMSD (Å) : 0.650 +/- 0.370

Consensus geometry
d (Å): 11 delta (°): 90-135 theta (°): 90-135 rho (°): 0-45
Consensus Sequence: pXXXphX
(φψ)-conformation: aallabb
Pattern: [NW][R]xx[KQRT][HNQ]x[GNS][AGS][KNQR][LMV]x[CVY][FY][A]
Conservation:0.9131.924-0.837-0.304-0.7760.308-1.214-0.342-0.426-0.4510.020-0.997-0.7451.7491.179
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a28_A_7441a28   A765779WRSYKHVSGQMLYFAHHHHHHHTTSSEEEEaaaaaaalvabxxab
1f2d_A_221f2d   A2236NRLSQHLGSKVNVYAHHHHHHTTT-SEEEEaaaaaaavlabbxbb
1gs4_A_7301gs4   A751765WRSFTNVNSRMLYFAHHHHHHHTTSSEEEEaaaaaaalvabxxab
1nhz_A_5891nhz   A610624WRSYRQSSANLLCFAHHHHHHHTTSSEEEEaaaaaaalvabxbab
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1a28_A_7441a28   A     STRPROGESTERONE W - 755
1a28_A_7441a28   A     STRPROGESTERONE M - 756
1a28_A_7441a28   A     STRPROGESTERONE M - 759
1a28_A_7441a28   A     STRPROGESTERONE V - 760
1a28_A_7441a28   A     STRPROGESTERONE G - 762
1a28_A_7441a28   A     STRPROGESTERONE L - 763
1a28_A_7441a28   A     STRPROGESTERONE R - 766
1a28_A_7441a28   A     STRPROGESTERONE Y - 777
1a28_A_7441a28   A     STRPROGESTERONE F - 778
1gs4_A_7301gs4   A     ZK59ALPHA-FLUOROCORTISOL W - 741
1gs4_A_7301gs4   A     ZK59ALPHA-FLUOROCORTISOL M - 742
1gs4_A_7301gs4   A     ZK59ALPHA-FLUOROCORTISOL M - 745
1gs4_A_7301gs4   A     ZK59ALPHA-FLUOROCORTISOL V - 746
1gs4_A_7301gs4   A     ZK59ALPHA-FLUOROCORTISOL M - 749
1gs4_A_7301gs4   A     ZK59ALPHA-FLUOROCORTISOL R - 752
1gs4_A_7301gs4   A     ZK59ALPHA-FLUOROCORTISOL Y - 763
1gs4_A_7301gs4   A     ZK59ALPHA-FLUOROCORTISOL F - 764
1gs4_A_7301gs4   A     ZK59ALPHA-FLUOROCORTISOL A - 765
1nhz_A_5891nhz   A     HEZHEXANE-1,6-DIOL L - 596
1nhz_A_5891nhz   A     HEZHEXANE-1,6-DIOL Q - 597
1nhz_A_5891nhz   A     HEZHEXANE-1,6-DIOL Y - 598
1nhz_A_5891nhz   A     HEZHEXANE-1,6-DIOL S - 599
1nhz_A_5891nhz   A     48611-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE W - 600
1nhz_A_5891nhz   A     HEZHEXANE-1,6-DIOL W - 600
1nhz_A_5891nhz   A     48611-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE M - 601
1nhz_A_5891nhz   A     HEZHEXANE-1,6-DIOL M - 601
1nhz_A_5891nhz   A     HEZHEXANE-1,6-DIOL S - 602
1nhz_A_5891nhz   A     HEZHEXANE-1,6-DIOL L - 603
1nhz_A_5891nhz   A     48611-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE M - 604
1nhz_A_5891nhz   A     HEZHEXANE-1,6-DIOL M - 604
1nhz_A_5891nhz   A     48611-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE A - 605
1nhz_A_5891nhz   A     HEZHEXANE-1,6-DIOL A - 607
1nhz_A_5891nhz   A     48611-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE L - 608
1nhz_A_5891nhz   A     48611-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE R - 611
1nhz_A_5891nhz   A     HEZHEXANE-1,6-DIOL R - 611
1nhz_A_5891nhz   A     48611-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE L - 621
1nhz_A_5891nhz   A     48611-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE C - 622
1nhz_A_5891nhz   A     48611-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE F - 623
1nhz_A_5891nhz   A     HEZHEXANE-1,6-DIOL F - 623
1nhz_A_5891nhz   A     48611-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE A - 624
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gs4_A_7301gs4   A AC1ZK5 BINDING SITE FOR CHAIN AR - 752

Clusters included in this Subclass
CLUSTER: HE.4.164