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Information on SUBCLASS 3.1.2
Subclass Accession number: 573
Subclass: 3.1.2 PSSM
Type: HA beta-beta hairpin
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 1.5 (>50 %)  1.5.1 (>50 %)  1.5.1.3
GO : GO:0004146 (>50 %)  GO:0016645 (>50 %)  GO:0016646 (>50 %)  
SCOP : 53596 (>50 %)  53597 (>50 %)  53598 (>50 %)  
 Number of loops: 3

Average sequence ID (%) : 21.2 +/- 29.0
Average RMSD (Å) : 0.700 +/- 0.265

Consensus geometry
d (Å): 7 delta (°): 90-135 theta (°): 90-135 rho (°): 45-90
Consensus Sequence: XXpphXh
(φψ)-conformation: bpaagpa
Pattern: [IV][TVW][AF]x[AGT][NT][NS][GY][GKV][IY][GL]
Conservation:1.740-0.593-0.277-0.808-0.4851.0011.1240.351-1.5620.349-0.841
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1df7_A_21df7   A515IWAQATSGVIGEEEEETTSEEEbbbbxaagxab
1jlx_A_1651jlx   A165175VTFKGNNGKYLEEEE-TTS-EEbbbbxaavxbx
4cd2_A_74cd2   A1020IVALTTSYGIGEEEEETT-EEEbbbbxaavxab
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1df7_A_21df7   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE I - 5
1df7_A_21df7   A     MTXMETHOTREXATE I - 5
1df7_A_21df7   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE W - 6
1df7_A_21df7   A     MTXMETHOTREXATE W - 6
1df7_A_21df7   A     GOLGLYCEROL W - 6
1df7_A_21df7   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE A - 7
1df7_A_21df7   A     MTXMETHOTREXATE A - 7
1df7_A_21df7   A     GOLGLYCEROL A - 7
1df7_A_21df7   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Q - 8
1df7_A_21df7   A     GOLGLYCEROL Q - 8
1df7_A_21df7   A     GOLGLYCEROL A - 9
1df7_A_21df7   A     GOLGLYCEROL T - 10
1df7_A_21df7   A     GOLGLYCEROL S - 11
1df7_A_21df7   A     GOLGLYCEROL G - 12
1df7_A_21df7   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE V - 13
1df7_A_21df7   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE I - 14
1df7_A_21df7   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE G - 15
4cd2_A_74cd2   A     FOLFOLIC ACID I - 10
4cd2_A_74cd2   A     FOLFOLIC ACID V - 11
4cd2_A_74cd2   A     FOLFOLIC ACID A - 12
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
4cd2_A_74cd2   A S1THE BINDING ORIENTATION OF THE PTERIDINE RING OF FOL IN THIS STRUCTURE IS SIMILAR TO THAT OBSERVED IN HDHFR FA BINARY COMPLEXES.I - 10

Clusters included in this Subclass
CLUSTER: HA.4.188