ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 6.59.1

Subclass Accession number: 5924
Subclass: 6.59.1

Type: HE alpha-beta
DB: ArchDB95

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 1.2 (>50 %)  1.2.1 (>50 %)
GO : GO:0016620 (>50 %)  GO:0016903 (>50 %)
SCOP : 53719 (>75 %)  53720 (>75 %)  53721 (>75 %)

Number of loops: 3

Average sequence ID (%) : 48.3 +/- 8.6
Average RMSD (Å) : 0.233 +/- 0.058

Consensus geometry

d (Å): 11

delta (°): 45-90

theta (°): 135-180

rho (°): 0-45

Consensus Sequence:	ANcpXhGLXX
(φψ)-conformation:	aapbapaabb

Pattern:	x	[AE]	[E]	[AV]	[LV]	[EGQ]	x	[A]	[N]	[DN]	[ST]	[PT]	[FY]	[G]	[L]	[AT]	[AGS]	[AG]	[V]	[FY]
Conservation:	-1.744	-0.789	1.116	-0.694	-0.371	-1.132	-1.388	0.503	1.729	0.233	-0.142	-0.460	1.109	1.729	0.503	-0.584	-0.859	-0.204	0.503	0.941

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a4s_A_414	1a4s	A	414	433	EEEVLQRANNTTFGLASGVF	HHHHHHHHH-SS--SEEEEE	aaaaaaaaaxbaxaabbbbb
1o04_A_413	1o04	A	413	432	IEEVVGRANNSTYGLAAAVF	HHHHHHHHH-SS--SEEEEE	aaaaaaaaaxbaxaabbbbb
1uzb_A_431	1uzb	A	431	450	FAEALEVANDTPYGLTGGVY	HHHHHHHHH-SS--SEEEEE	aaaaaaaaaxbabaabbbbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1o04_A_413	1o04	A	EDO1,2-ETHANEDIOL	V - 417
1o04_A_413	1o04	A	NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE	L - 427
1uzb_A_431	1uzb	A	MRD(4R)-2-METHYLPENTANE-2,4-DIOL	P - 442

Clusters included in this Subclass

CLUSTER: HE.5.321