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Information on SUBCLASS 2.2.55
Subclass Accession number: 6100
Subclass: 2.2.55 PSSM
Type: HA beta-beta hairpin
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 2.7 (>75 %)  2.7.1 (>75 %)  2.7.1.37
GO : GO:0004672 (>75 %)  GO:0004702 (>75 %)  GO:0004707 (>75 %)  GO:0005057 (>75 %)  GO:0005524 (>75 %)  GO:0016301 (>75 %)  GO:0016772 (>75 %)  GO:0016773 (>75 %)  GO:0016909 (>75 %)  GO:0017076 (>75 %)  GO:0030554 (>75 %)  
SCOP : 56111 (>75 %)  56112 (>75 %)  88854 (>75 %)  
Number of loops: 2

Average sequence ID (%) : 52.9 +/- 0.0
Average RMSD (Å) : 0.100 +/- 0.000

Consensus geometry
d (Å): 7 delta (°): 90-135 theta (°): 90-135 rho (°): 135-180
Consensus Sequence: VhpRYQ
(φψ)-conformation: bpaabb
Pattern: [ST][IT][FW][ET][V][LP][EK][R][Y][Q][N][L][KS][P][IV][G][S]
Conservation:-0.742-1.3020.379-1.162-0.041-1.582-0.6010.5191.6400.5191.079-0.041-1.0221.640-0.3211.079-0.041
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1pmq_A_561pmq   A5672STFTVLKRYQNLKPIGSEEEEEETTEEEEEEEEEbbxbbxaabblxbwaeb
1r3c_A_161r3c   A1632TIWEVPERYQNLSPVGSEEEEEETTEEEEEEEEEbxbbbxaaxblxbwaeb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1pmq_A_561pmq   A     880CYCLOHEXYL-{4-[5-(3,4-DICHLOROPHENYL)-2-PIPERIDIN-4-YL -3-PROPYL-3H-IMIDAZOL-4-YL]-PYRIMIDIN-2-YL}AMINE I - 70
1pmq_A_561pmq   A     880CYCLOHEXYL-{4-[5-(3,4-DICHLOROPHENYL)-2-PIPERIDIN-4-YL -3-PROPYL-3H-IMIDAZOL-4-YL]-PYRIMIDIN-2-YL}AMINE G - 71
1pmq_A_561pmq   A     ANPPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER S - 72
1pmq_A_561pmq   A     880CYCLOHEXYL-{4-[5-(3,4-DICHLOROPHENYL)-2-PIPERIDIN-4-YL -3-PROPYL-3H-IMIDAZOL-4-YL]-PYRIMIDIN-2-YL}AMINE S - 72

Clusters included in this Subclass
CLUSTER: HA.1.96