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Information on SUBCLASS 6.2.3
Subclass Accession number: 6430
Subclass: 6.2.3 PSSM
Type: HA beta-beta hairpin
DB: ArchDB95

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 1 (>75 %)  
 Number of loops: 6

Average sequence ID (%) : 7.7 +/- 9.6
Average RMSD (Å) : 0.817 +/- 0.256

Consensus geometry
d (Å): 7 delta (°): 90-135 theta (°): 135-180 rho (°): 270-315
Consensus Sequence: XpXXXXXXXX
(φψ)-conformation: bbpaaalpbb
Pattern: [dhsy][dgknt][FKQR][cdkr][dpr]x[cmt][gkm]x[dkwy]x[fkrwy][fhivy]
Conservation:0.053-1.1871.802-0.7931.527-0.5681.2730.516-0.142-0.865-1.132-0.297-0.186
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1eaz_A_1941eaz   A199211VKQGAVMKNWKRREEE-TTT--EEEEbbxxaaavxbbxb
1hyh_A_2691hyh   A274286SNRRDDMGMYLSYEEE-TTT-SEEEExbxxaaavbxbxb
1jj2_Z_161jj2   Z1628HTKCRRCGEKSYHEEE-TTT-SEEEExbpxaaavxxaxx
1jqp_A_3801jqp   A387399YGKDPVTGLDYWIEEE-TTT--EEEEbbbpaaavxxbbb
1l1l_A_4901l1l   A495507DDFDPETHEAIKVEEE-TTT--EEEExbbxaaavxxbbb
1qqg_A_131qqg   A1830YLRKPKSMHKRFFEEE-TTT--EEEExbbxaaalxxbxx
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1eaz_A_1941eaz   A     CITCITRIC ACID K - 200
1eaz_A_1941eaz   A     CITCITRIC ACID Q - 201
1eaz_A_1941eaz   A     CITCITRIC ACID G - 202
1eaz_A_1941eaz   A     CITCITRIC ACID A - 203
1eaz_A_1941eaz   A     CITCITRIC ACID V - 204
1eaz_A_1941eaz   A     CITCITRIC ACID K - 209
1eaz_A_1941eaz   A     CITCITRIC ACID R - 211
1jj2_Z_161jj2   Z     CDCADMIUM ION C - 19
1jj2_Z_161jj2   Z     CDCADMIUM ION R - 20
1jj2_Z_161jj2   Z     CDCADMIUM ION R - 21
1jj2_Z_161jj2   Z     CDCADMIUM ION C - 22
1jj2_Z_161jj2   Z     CDCADMIUM ION G - 23
1jj2_Z_161jj2   Z     CDCADMIUM ION E - 24
1jj2_Z_161jj2   Z     CDCADMIUM ION S - 26
1jj2_Z_161jj2   Z     CDCADMIUM ION Y - 27
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1eaz_A_1941eaz   A LBSLBS STANDS FOR LIPID BINDING SITE. CB ATOM RESPONSIBLE FOR THE NOVEL SPECIFICITY OF THIS DOMAIN. THE ALANINE AT A1024 (203) IN TAPP1, IN DAPP1 ID A GLY, WHICH CAN BIND BOTH (3,4)P2, AND (3,4,5) P3K - 200
1eaz_A_1941eaz   A LBSLBS STANDS FOR LIPID BINDING SITE. CB ATOM RESPONSIBLE FOR THE NOVEL SPECIFICITY OF THIS DOMAIN. THE ALANINE AT A1024 (203) IN TAPP1, IN DAPP1 ID A GLY, WHICH CAN BIND BOTH (3,4)P2, AND (3,4,5) P3G - 202
1eaz_A_1941eaz   A LBSLBS STANDS FOR LIPID BINDING SITE. CB ATOM RESPONSIBLE FOR THE NOVEL SPECIFICITY OF THIS DOMAIN. THE ALANINE AT A1024 (203) IN TAPP1, IN DAPP1 ID A GLY, WHICH CAN BIND BOTH (3,4)P2, AND (3,4,5) P3A - 203
1eaz_A_1941eaz   A LBSLBS STANDS FOR LIPID BINDING SITE. CB ATOM RESPONSIBLE FOR THE NOVEL SPECIFICITY OF THIS DOMAIN. THE ALANINE AT A1024 (203) IN TAPP1, IN DAPP1 ID A GLY, WHICH CAN BIND BOTH (3,4)P2, AND (3,4,5) P3R - 211

Clusters included in this Subclass
CLUSTER: HA.6.176
CLUSTER: HA.7.54