ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.2.6

Subclass Accession number: 646
Subclass: 4.2.6

Type: HA beta-beta hairpin
DB: ArchDB40

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 21 (>50 %)  3 (>50 %)  4 (>50 %)
GO : GO:0004252 (>75 %)  GO:0008236 (>75 %)
SCOP : 50493 (>75 %)  50494 (>75 %)  50514 (>50 %)

Number of loops: 7

Average sequence ID (%) : 12.1 +/- 14.1
Average RMSD (Å) : 0.671 +/- 0.415

Consensus geometry

d (Å): 5

delta (°): 90-135

theta (°): 135-180

rho (°): 180-225

Consensus Sequence:	hXpphpXX
(φψ)-conformation:	bbaagpbb

Pattern:	x	[ekl]	[ailvw]	x	[DEHQST]	[DNSY]	[eg]	[dhknst]	[CFTV]	x	[imvy]
Conservation:	-1.147	-0.364	-0.844	-0.176	0.729	1.320	1.874	-0.559	0.295	-1.267	0.139

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1d3b_A_27	1d3b	A	33	43	IEAEDNMNCQM	EEE-TT--EEE	abbbaavxbxb
1dn0_B_46	1dn0	B	49	59	GEINHSGSTNY	EEE-TT--EEE	bbbbaagxbbb
1em2_A_260	1em2	A	262	272	EKNNEYGDTVY	EEE-TT--EEE	abbbaavxbbb
1k82_A_92	1k82	A	93	103	DLVMSNGKVLR	EEEETTS-EEE	bbxxaavxbxb
1lci_*_418	1lci	-	424	434	AYWDEDEHFFI	EEE-TT--EEE	bbbxaavxxbx
1qi9_A_528	1qi9	A	529	539	IKLFQDGTFTI	EEEETTS-EEE	bbbbaagxbbb
1qmh_A_326	1qmh	A	326	336	SLIETDGVTRV	EEEE-SS-EEE	bbbxaavbbxb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1d3b_A_27	1d3b	A	GOLGLYCEROL	R - 29
1d3b_A_27	1d3b	A	GOLGLYCEROL	T - 47
1d3b_A_27	1d3b	A	GOLGLYCEROL	V - 48
1d3b_A_27	1d3b	A	GOLGLYCEROL	T - 49
1em2_A_260	1em2	A	MSESELENOMETHIONINE	D - 269
1em2_A_260	1em2	A	MSESELENOMETHIONINE	V - 271

Clusters included in this Subclass

CLUSTER: HA.4.118

CLUSTER: HA.5.66