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Information on SUBCLASS 4.5.2
Subclass Accession number: 656
Subclass: 4.5.2 PSSM
Type: HA beta-beta hairpin
DB: ArchDB40

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 3.4.23 (>75 %)  3.4.23.24
GO : GO:0004190 (>75 %)  GO:0016168 (>75 %)  GO:0042314 (>75 %)  GO:0046906 (>75 %)  
SCOP : 50345 (>75 %)  50346 (>75 %)  50347 (>75 %)  50629 (>75 %)  50630 (>75 %)  50646 (>75 %)  
 Number of loops: 4

Average sequence ID (%) : 13.9 +/- 13.9
Average RMSD (Å) : 0.900 +/- 0.294

Consensus geometry
d (Å): 7 delta (°): 90-135 theta (°): 135-180 rho (°): 270-315
Consensus Sequence: hpXcchXh
(φψ)-conformation: bbpllpbb
Pattern: x[CGIL]x[CEY][KLV][HS]x[GKN][GKN][AL]xx[EST][FGLY]xxxx
Conservation:-0.883-1.029-1.0290.0640.0651.5982.0220.8370.8371.275-0.518-0.7370.939-0.591-0.299-0.568-0.956-1.029
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1gzq_A_941gzq   A100117AGCELHSGGAIVSFLRGAEEEEE-TTS-EEEEEEEEbbbbxxxggxbxbbbbbb
1i3z_A_401i3z   A4057LCLCVSFKKLVYSYRIFREEEEEE-SSSEEEEEEEEbbxbbxblvbxbbbxbbx
1l7a_A_541l7a   A5875RLTYKSFGNARITGWYAVEEEEEEGGGEEEEEEEEEbbbbxbpvlxxbbexbbb
1vjp_A_2891vjp   A295312HIEYVSFNGATDELMINGEEEEE-GGG-EEEEEEEEbbbbbbxlvxbbbbbbbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1gzq_A_941gzq   A     D12DODECANE F - 94
1gzq_A_941gzq   A     D12DODECANE I - 96
1gzq_A_941gzq   A     TWTDOCOSANE I - 96
1gzq_A_941gzq   A     TWTDOCOSANE Q - 97
1gzq_A_941gzq   A     TWTDOCOSANE G - 98
1gzq_A_941gzq   A     TWTDOCOSANE I - 99
1gzq_A_941gzq   A     PII2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE A - 100
1gzq_A_941gzq   A     TWTDOCOSANE A - 100
1gzq_A_941gzq   A     PII2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE G - 101
1gzq_A_941gzq   A     PII2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE C - 102
1gzq_A_941gzq   A     PII2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE F - 113
1gzq_A_941gzq   A     PII2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE L - 114
1gzq_A_941gzq   A     TWTDOCOSANE L - 114
1gzq_A_941gzq   A     TWTDOCOSANE R - 115
1gzq_A_941gzq   A     TWTDOCOSANE G - 116
1gzq_A_941gzq   A     TWTDOCOSANE A - 117
1gzq_A_941gzq   A     D12DODECANE L - 118
1gzq_A_941gzq   A     TWTDOCOSANE L - 118
1i3z_A_401i3z   A     PTRO-PHOSPHOTYROSINE C - 41
1i3z_A_401i3z   A     PTRO-PHOSPHOTYROSINE V - 50
1i3z_A_401i3z   A     PTRO-PHOSPHOTYROSINE Y - 51
1i3z_A_401i3z   A     PTRO-PHOSPHOTYROSINE S - 52
1i3z_A_401i3z   A     PTRO-PHOSPHOTYROSINE Y - 53
1i3z_A_401i3z   A     PTRO-PHOSPHOTYROSINE R - 54
1vjp_A_2891vjp   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE K - 290
1vjp_A_2891vjp   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 315

Clusters included in this Subclass
CLUSTER: HA.4.178
CLUSTER: HA.6.121