Information on SUBCLASS 12.4.1 |
Subclass Accession number: 6593
Subclass: 12.4.1 ![]() Type: HA beta-beta hairpin DB: ArchDB95 Image coordinates: ![]() ![]() Consensus coordinates: ![]() ![]() Conserved Annotation EC : 3.4 (>75 %) 3.4.21 (>75 %) 3.4.21 (>75 %) 3.4.21.4 GO : GO:0004175 (>75 %) GO:0004252 (>75 %) GO:0004252 (>75 %) GO:0005509 (>75 %) GO:0008233 (>75 %) GO:0008236 (>75 %) GO:0008236 (>75 %) SCOP : 50493 (>75 %) 50493 (>75 %) 50494 (>75 %) 50494 (>75 %) 50514 (>75 %) 50514 (>75 %) |
Number of loops: 7 Average sequence ID (%) : 74.2 +/- 16.1 Average RMSD (Å) : 0.257 +/- 0.113 Consensus geometry
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Consensus Sequence: | RLGEHNIpVXEGpEQF |
(φψ)-conformation: | bblpapaabpagapbb |
Pattern: | [EQ] | [V] | [R] | [L] | [G] | [E] | [DH] | [N] | [I] | [ADEKN] | [V] | [ltv] | [E] | [G] | [NST] | [E] | [Q] | [F] | [IV] | [DNS] | [AS] | [ASV] | [KR] | [iv] | [I] | x |
Conservation: | -0.006 | 0.207 | 0.774 | 0.207 | 1.341 | 0.774 | -0.010 | 1.341 | 0.207 | -1.584 | 0.207 | -1.817 | 0.774 | 1.341 | -0.784 | 0.774 | 0.774 | 1.341 | -0.049 | -0.808 | -0.639 | -1.445 | -0.006 | -1.306 | 0.207 | -1.819 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1a0j_A_64 | 1a0j | A | 64 | 89 | QVRLGEHNIAVNEGTEQFIDSVKVIM | EEEES-SBSSS--S--EEEEEEEEEE | xxbbvxabaabxavaxbbbxxabbbx |
1f7z_A_64 | 1f7z | A | 64 | 89 | QVRLGEHNINVLEGNEQFVNAAKIIK | EEEES-SBTTS--S--EEEEEEEEEE | bxbbvxaxaabxagaxbbbxxabbbx |
1h4w_A_64 | 1h4w | A | 64 | 89 | QVRLGEHNIKVLEGNEQFINAVKIIR | EEEES-SBTTS--S--EEEEEEEEEE | bxbbvxaxaabxagaxbbbxxabbbx |
1hj8_A_64 | 1hj8 | A | 64 | 89 | EVRLGEHNIKVTEGSEQFISSSRVIR | EEEES-SBTTS--S--EEEEEEEEEE | xxbbvxabaabxavaxbbbxxabbbx |
1hj9_A_64 | 1hj9 | A | 64 | 89 | QVRLGEDNINVVEGNEQFISASKSIV | EEEES-SSTTS--S--EEEEEEEEEE | bxbbvxaxaabxagaxbbbxxabbbx |
1s83_A_64 | 1s83 | A | 64 | 89 | QVRLGEHNIDVLEGNEQFINAAKIIT | EEEES-SBTTS--S--EEEEEEEEEE | bxbbvxaxaabxGNaxbbbxxabbbx |
1trn_A_64 | 1trn | A | 64 | 89 | QVRLGEHNIEVLEGNEQFINAAKIIR | EEEES-SBSSS--S--EEEEEEEEEE | xxbbvxaxaabpagaxbbbxxabbbx |
PDB ligands within a cut-off distance of 6 Å in this subclass |
Loop | PDB | Chain | Ligands | Residue |
1a0j_A_64 | 1a0j | A | CACALCIUM ION | R - 66 |
1hj8_A_64 | 1hj8 | A | BAMBENZAMIDINE | E - 64 |
1hj8_A_64 | 1hj8 | A | BAMBENZAMIDINE | R - 66 |
1hj9_A_64 | 1hj9 | A | CACALCIUM ION | V - 75 |
Clusters included in this Subclass |
CLUSTER: HA.11.5 |