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Information on SUBCLASS 1.2.1
Subclass Accession number: 6628
Subclass: 1.2.1 PSSM
Type: AR beta-beta link
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 79

Average sequence ID (%) : 10.7 +/- 14.3
Average RMSD (Å) : 0.314 +/- 0.152

Consensus geometry
d (Å): 9 delta (°): 45-90 theta (°): 45-90 rho (°): 90-135
Consensus Sequence: hXXXX
(φψ)-conformation: bblbb
Pattern: xx[acfgilmvwy]x[adgknqrst]xx[acfilmvy]x
Conservation:-1.000-0.5130.073-0.5431.199-0.634-0.7431.879-0.718
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1agj_A_841agj   A8592SFRPSINT.EEEET-EE.bbbxlxbb.
1air_*_1131air   -113121VVVQNMRIGEEEES-EEEbbbblbbbb
1air_*_1411air   -141149VWVDHNELFEEEES-EEEbbbblbbbb
1air_*_2041air   -205213ITYHHNYYNEEEES-EEEbbbbvxbbb
1air_*_2261air   -227235VHAYNNLYTEEEES-EEEbbbblbbbb
1air_*_2491air   -250258ALIENNWFEEEEES-EEEbbbblbbbb
1ayl_*_3091ayl   -309315.LLENVTV..EEES-EE..bxblxxb.
1bhe_*_2101bhe   -212220ITIAYSNIAEEEES-EEEbbbblbbbb
1bn8_A_1391bn8   A139146.KVVGGNFQ.EEES-EEE.bbbvxbxb
1bn8_A_1501bn8   A152160VIIRNIEFQEEEES-EEEbbbbvbxbb
1bn8_A_1921bn8   A194202IWIDHCTFNEEEES-EEEbbbblbbbb
1bn8_A_2331bn8   A235243ITMSYNYYHEEEES-EEEbbbblxbbb
1bn8_A_2661bn8   A266274ITLHHNRYKEEEES-EEEbbbblxbbb
1bn8_A_2871bn8   A288296VHVYNNYYEEEEES-EEEbxbblbbbb
1bn8_A_3171bn8   A318326IYAQNNVIDEEEES-EEExbbblbbbb
1bn8_A_3461bn8   A346352.YDSGTLL..EEES-EE..bbbvxbb.
1bob_*_491bob   -4955..YKDLIIH..EES-EEE..bblxbbx
1c4k_A_6981c4k   A698704..IQGVYFK..EESSEEE..bbvbbxb
1c8k_A_2131c8k   A213221AKWVDTQVVEEEES-EEExbxblxxbb
1cqq_A_1301cqq   A130138NQTARMLKYEEE-SEEEExxbxlxxbb
1czf_A_1371czf   A137145SSITGLNIKEEEES-EEEbbbbvxbbb
1czf_A_1591czf   A159167ITFTDVTINEEEES-EEEbbbblxbbx
1czf_A_1881czf   A190198VNIIKPWVHEEEES-EEEbbbblxbbb
1czf_A_2091czf   A212220IWFTGGTCIEEEES-EEEbbbbvxbbb
1czf_A_471czf   A4855ITLNNIEV.EEEES-EE.bbxxlxbx.
1czf_A_981czf   A100108TGASGHLINEE-TT-EEEbbxpvxbbb
1dbg_A_1291dbg   A129136.RITACVFD.EEES-EEE.bbblbbbb
1dbg_A_1611dbg   A161168.RIDHCSFT.EEES-EEE.bbblbbbb
1dbg_A_1991dbg   A199206.RVDHCFFS.EEES-EEE.bbblbbbb
1dbg_A_2311dbg   A231238.LVDSNLFM.EEES-EEE.bbblbbbb
1dbg_A_2551dbg   A255262.VYYGNTYL.EEES-EEE.bbbvxbbb
1dbg_A_2771dbg   A277284.VAINNFYI.EEES-EEE.bbblxbbb
1dbg_A_3031dbg   A303310.VIACNYFE.EEES-EEE.bbblxbbb
1dbg_A_3401dbg   A340348MLIANNAFIEEEES-EEEbbbblxbbb
1dbg_A_3811dbg   A381389LMLKGNLFFEEEES-EEExbbblxbbb
1dbg_A_4101dbg   A410417.SWTGNVAL.EEES-EEE.bbbvxbbb
1dbg_A_521dbg   A5260GTYKDVQLIEEEET-EEEebbxvxbxb
1dbg_A_961dbg   A96104LILEGIWFKEEEES-EEEbbbbvbbxb
1f0l_A_121f0l   A1220FVMENFSSYEEEET-EEEbbbxlxbbb
1f8r_A_2551f8r   A255262.VHFNAQVI.EESS-EEE.bbxlbxxa
1gq8_A_1441gq8   A145153QFFINCFIAEEEES-EEEbbbblbbbb
1gq8_A_1641gq8   A165173VVLQDCDIHEEEES-EEEbbbblbbbb
1gq8_A_1981gq8   A199207IVIQKSRIGEEEES-EEEbbbblbbbb
1gq8_A_2321gq8   A233240TVVMQSSI.EEEES-EE.bbbblbbb.
1h2w_A_1621h2w   A169177ERVKFSCMAEEE-S--EEbvxblbxbb
1hg8_A_1391hg8   A139147SKITNLNIQEEEES-EEExbbbvbbbb
1hg8_A_3451hg8   A348356FTFSGNAITEEEES-EEExbbbvxbxb
1hv9_A_2971hv9   A297303.VIKNSVI..EEES-EE..bbblbbb.
1idk_*_1881idk   -189197VSLTNNYIDEEEES-EEEbbbblxbxx
1jta_A_1141jta   A116124VIIRNVYIQEEEES-EEEbbbblbbbx
1jta_A_1941jta   A196204VTISNSLIDEEEES-EEEbbbblbbbb
1jta_A_2271jta   A228236VTLFNNVFNEEEES-EEEbbbblbbbb
1jta_A_2791jta   A280288VLSEGNSFTEEEES-EEEbbbblxbbb
1jta_A_3081jta   A309316FSDNGSVL.EEEES-EE.bbbbvxbb.
1jta_A_991jta   A99106.KFINGSLI.EEESSEEE.bbblbbbb
1k32_A_1321k32   A132139.RMFTDVAG.EE-SEEEE.bxxvbxae
1l5r_A_2131l5r   A213221TKWIDTQVVEEEES-EEExbbblxxbb
1lpf_A_2371lpf   A237245NIRLGARVTEEETT-EEExxbxlbxxa
1lvl_*_2281lvl   -228236ALHLGHSVEEEETT-EEExbxxvxbxa
1mo9_A_2711mo9   A271279EIISGSNVTEEESS-EEEbbbxlbbxa
1n2s_A_1461n2s   A149155FRTSWVY..EEE-SEE..bxbblxb..
1nhc_A_1031nhc   A105113TMADGAVIDEE-TT-EEEbbxpvxbbb
1nhc_A_1941nhc   A196204VYISGATVKEEEES-EEEbbbbvxbbb
1nhc_A_521nhc   A5360VVLSSIEV.EEEES-EE.bbbxlxxx.
1nhc_A_991nhc   A99105..GKDLTVT..EES-EEE..eblxbbb
1ogo_X_3331ogo   X335343WYCVGPTINEEEES-EEExbbbgpbbb
1ps9_A_5891ps9   A589597KMIPGVSYQEEE-S-EEEbbbxvxbxa
1qcx_A_1351qcx   A135143VIIQNIAVTEEEES-EEEbbbblbbbb
1qcx_A_1641qcx   A164172VWIDHVTTAEEEES-EEEbbbblbbbb
1qcx_A_1871qcx   A189197VTISYSLIDEEEES-EEEbbbblbbbx
1qcx_A_2211qcx   A223231VTLKGNYFYEEEES-EEEbbbblxbbb
1qjv_A_1861qjv   A187195SFFSDCRISEEEES-EEEbbbblbbbb
1qjv_A_2061qjv   A207215ALFNNCDLVEEEES-EEEbbbblbxxx
1qjv_A_2441qjv   A244252LVITNSRVIEEEES-EEExbbblbbxb
1qjv_A_2881qjv   A289296TVFLNTSM.EEEES-EE.bbbblbxb.
1qq1_A_1891qq1   A189196.RIAGVFME.EEES-EEE.bbbvpbxb
1qq1_A_3481qq1   A348355.GVIGFTSY.EEES-EEE.ebbvbbbb
1qre_A_731qre   A7381NVQDGVVLHEE-TT-EEEbbxxvxbbb
1trb_*_1991trb   -200208ILHTNRTLEEEE-S-EEEbxbxlbbxa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1cqq_A_1301cqq   A     AG74-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE -3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER N - 130
1cqq_A_1301cqq   A     AG74-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE -3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER T - 132
1czf_A_1881czf   A     NAGN-ACETYL-D-GLUCOSAMINE G - 189
1czf_A_1881czf   A     NAGN-ACETYL-D-GLUCOSAMINE V - 190
1czf_A_1881czf   A     NAGN-ACETYL-D-GLUCOSAMINE N - 191
1czf_A_2091czf   A     NAGN-ACETYL-D-GLUCOSAMINE E - 210
1czf_A_2091czf   A     NAGN-ACETYL-D-GLUCOSAMINE N - 211
1czf_A_2091czf   A     NAGN-ACETYL-D-GLUCOSAMINE I - 212
1czf_A_2091czf   A     NAGN-ACETYL-D-GLUCOSAMINE W - 213
1dbg_A_1611dbg   A     GCUD-GLUCURONIC ACID R - 161
1dbg_A_1611dbg   A     GCUD-GLUCURONIC ACID H - 164
1dbg_A_1991dbg   A     MANALPHA-D-MANNOSE R - 199
1dbg_A_1991dbg   A     GCUD-GLUCURONIC ACID R - 199
1dbg_A_1991dbg   A     MANALPHA-D-MANNOSE D - 201
1dbg_A_1991dbg   A     GCUD-GLUCURONIC ACID D - 201
1dbg_A_1991dbg   A     MANALPHA-D-MANNOSE H - 202
1dbg_A_1991dbg   A     GCUD-GLUCURONIC ACID H - 202
1dbg_A_2311dbg   A     MANALPHA-D-MANNOSE D - 233
1dbg_A_2311dbg   A     GCUD-GLUCURONIC ACID D - 233
1dbg_A_2311dbg   A     MANALPHA-D-MANNOSE S - 234
1dbg_A_2311dbg   A     RAMRHAMNOSE S - 234
1dbg_A_2311dbg   A     GCUD-GLUCURONIC ACID S - 234
1dbg_A_2551dbg   A     MANALPHA-D-MANNOSE Y - 257
1dbg_A_2551dbg   A     RAMRHAMNOSE Y - 257
1dbg_A_2551dbg   A     GCUD-GLUCURONIC ACID Y - 257
1dbg_A_2551dbg   A     MANALPHA-D-MANNOSE G - 258
1dbg_A_2551dbg   A     RAMRHAMNOSE G - 258
1dbg_A_2551dbg   A     RAMRHAMNOSE N - 259
1dbg_A_2551dbg   A     RAMRHAMNOSE T - 260
1dbg_A_2771dbg   A     RAMRHAMNOSE I - 279
1dbg_A_2771dbg   A     RAMRHAMNOSE N - 280
1dbg_A_2771dbg   A     RAMRHAMNOSE F - 282
1f0l_A_121f0l   A     APUADENYLYL-3'-5'-PHOSPHO-URIDINE-3'-MONOPHOSPHATE Y - 20
1f0l_A_121f0l   A     APUADENYLYL-3'-5'-PHOSPHO-URIDINE-3'-MONOPHOSPHATE H - 21
1f0l_A_121f0l   A     APUADENYLYL-3'-5'-PHOSPHO-URIDINE-3'-MONOPHOSPHATE G - 22
1f0l_A_121f0l   A     APUADENYLYL-3'-5'-PHOSPHO-URIDINE-3'-MONOPHOSPHATE T - 23
1f8r_A_2551f8r   A     FADFLAVIN-ADENINE DINUCLEOTIDE A - 259
1f8r_A_2551f8r   A     FADFLAVIN-ADENINE DINUCLEOTIDE Q - 260
1f8r_A_2551f8r   A     FADFLAVIN-ADENINE DINUCLEOTIDE V - 261
1f8r_A_2551f8r   A     FADFLAVIN-ADENINE DINUCLEOTIDE I - 262
1hg8_A_1391hg8   A     NAGN-ACETYL-D-GLUCOSAMINE K - 140
1l5r_A_2131l5r   A     700[5-CHLORO-1H-INDOL-2-CARBONYL-PHENYLALANINYL]-AZETIDINE-3-CARBOXYLIC ACID L - 224
1l5r_A_2131l5r   A     700[5-CHLORO-1H-INDOL-2-CARBONYL-PHENYLALANINYL]-AZETIDINE-3-CARBOXYLIC ACID Y - 226
1l5r_A_2131l5r   A     700[5-CHLORO-1H-INDOL-2-CARBONYL-PHENYLALANINYL]-AZETIDINE-3-CARBOXYLIC ACID D - 227
1l5r_A_2131l5r   A     700[5-CHLORO-1H-INDOL-2-CARBONYL-PHENYLALANINYL]-AZETIDINE-3-CARBOXYLIC ACID T - 228
1l5r_A_2131l5r   A     700[5-CHLORO-1H-INDOL-2-CARBONYL-PHENYLALANINYL]-AZETIDINE-3-CARBOXYLIC ACID P - 229
1lvl_*_2281lvl   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE H - 233
1lvl_*_2281lvl   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE S - 234
1lvl_*_2281lvl   *     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 235
1n2s_A_1461n2s   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 151
1n2s_A_1461n2s   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE S - 152
1n2s_A_1461n2s   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE W - 153
1n2s_A_1461n2s   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE V - 154
1n2s_A_1461n2s   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE Y - 155
1nhc_A_1941nhc   A     NAGN-ACETYL-D-GLUCOSAMINE Y - 197
1ps9_A_5891ps9   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Y - 596
1qre_A_731qre   A     BCTBICARBONATE ION H - 81
1qre_A_731qre   A     OCNCOBALT ION, 2 WATERS COORDINATED H - 81
1qre_A_731qre   A     BCTBICARBONATE ION A - 82
1qre_A_731qre   A     OCNCOBALT ION, 2 WATERS COORDINATED A - 82
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1f0l_A_121f0l   A CATREFERS TO CATALYTIC SITEH - 21

Clusters included in this Subclass
CLUSTER: AR.1.2
CLUSTER: AR.1.26
CLUSTER: AR.1.44
CLUSTER: AR.2.1
CLUSTER: AR.3.1
CLUSTER: AR.4.146