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Information on SUBCLASS 1.2.8
Subclass Accession number: 7087
Subclass: 1.2.8 PSSM
Type: EH beta-alpha
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 7

Average sequence ID (%) : 23.0 +/- 21.0
Average RMSD (Å) : 0.443 +/- 0.140

Consensus geometry
d (Å): 7 delta (°): 45-90 theta (°): 135-180 rho (°): 315-360
Consensus Sequence: hpGpX
(φψ)-conformation: bbeaa
Pattern: [FLVY][GILV][AGS][HRSTW][GS][DRSTY][epqs][GLVY]x[HILVY][acstv]x[AES][AGLV][ALY][adeks]x[hl]
Conservation:0.5880.0931.018-0.4433.061-0.630-0.528-0.420-1.341-0.218-0.284-0.7031.192-0.1080.316-0.654-0.900-0.038
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1gpu_A_5571gpu   A559576LVATGSEVSLSVEAAKTLEEE-THHHHHHHHHHHHHbbbbeaaaaaaaaaaaaa
1l8a_A_7241l8a   A728745LLGSGSILRHVREAAEILEEE-GGGHHHHHHHHHHHbbbbeaaaaaaaaaaaaa
1moq_*_4661moq   -469486FLGRGDQYPIALEGALKLEEE-GGGHHHHHHHHHHHbbbbeaaaaaaaaaaaaa
1ni4_B_2071ni4   B209226VVSHSRPVGHCLEAAAVLEEE-STHHHHHHHHHHHHbbbbeaaaaaaaaaaaaa
1ols_B_2221ols   B224241LVAWGTQVHVIREVASMAEEE-TTHHHHHHHHHHHHbbbbeaaaaaaaaaaaaa
1qgd_A_5521qgd   A554571FIATGSEVELAVAAYEKLEEE-GGGHHHHHHHHHHHxbbbeaaaaaaaaaaaaa
1ryp_K_1291ryp   K129146YGAHGYSGFYTFSLLDHHEEE-TTHHHHHHHHHHHHbbbbeaaaaaaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1moq_*_4661moq   *     MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID R - 472
1moq_*_4661moq   *     MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID D - 474
1moq_*_4661moq   *     MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID Q - 475
1moq_*_4661moq   *     MPD2-METHYL-2,4-PENTANEDIOL Y - 476
1moq_*_4661moq   *     MPD2-METHYL-2,4-PENTANEDIOL L - 480
1moq_*_4661moq   *     GLPGLUCOSAMINE 6-PHOSPHATE L - 484
1moq_*_4661moq   *     GLPGLUCOSAMINE 6-PHOSPHATE K - 485
1moq_*_4661moq   *     GLPGLUCOSAMINE 6-PHOSPHATE E - 488
1ni4_B_2071ni4   B     MSESELENOMETHIONINE T - 208
1ni4_B_2071ni4   B     MSESELENOMETHIONINE V - 210
1ni4_B_2071ni4   B     MSESELENOMETHIONINE S - 211
1ni4_B_2071ni4   B     MSESELENOMETHIONINE H - 212
1ni4_B_2071ni4   B     MSESELENOMETHIONINE S - 213
1ni4_B_2071ni4   B     MSESELENOMETHIONINE R - 214
1ni4_B_2071ni4   B     MSESELENOMETHIONINE V - 216

Clusters included in this Subclass
CLUSTER: EH.3.34
CLUSTER: EH.4.18