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Information on SUBCLASS 1.3.1
Subclass Accession number: 7099
Subclass: 1.3.1 PSSM
Type: EH beta-alpha
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 43

Average sequence ID (%) : 8.6 +/- 12.3
Average RMSD (Å) : 0.467 +/- 0.164

Consensus geometry
d (Å): 7 delta (°): 45-90 theta (°): 135-180 rho (°): 90-135
Consensus Sequence: hXXpX
(φψ)-conformation: bpaaa
Pattern: xx[acfgilmtv]xx[adegknqrst]x[afgiklmtv]xxxx
Conservation:-0.446-0.8961.488-0.616-1.0321.881-0.3741.284-0.707-0.6620.229-0.150
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a4s_A_3021a4s   A303314VFVQREIMPQFLEEEEGGGHHHHHxxbpaaaaaaaa
1a8h_*_2531a8h   -255266HLIGKDILKPHAEEEEGGGHHHHHbbbbaaaaaaaa
1aop_*_2721aop   -275286GYLPLEHTLAVAEEEEGGGHHHHHebbxaaaaaaaa
1ati_A_2341ati   A242253YFVRPGEDEYWHEEE-GGGHHHHHxxbxaaaaaaaa
1az9_*_1061az9   -106117RALAFSEINQQLEEEEGGGHHHHHbbbxaaaaaaaa
1b93_A_131b93   A1627LVAHDHCKQMLMEEE-GGGHHHHHbbbxaaaaaaaa
1cbf_*_2191cbf   -221232VRTTVKDLDDAMEEEEGGGHHHHHbbbbaaaaaaaa
1cdo_A_3461cdo   A348359HRMPLESVNDAIEEEEGGGHHHHHbbbxaaaaaaaa
1cf2_O_501cf2   O5162YVAIPERVKLFEEESSGGGHHHHHbbabaaaaaaaa
1cjw_A_1551cjw   A158169LMCEDALVPFYQEEE-GGGHHHHHbbbxaaaaaaaa
1cl1_A_2211cl1   A223234AVCNARCWEQLREEE-TTTHHHHHbxbxaaaaaaaa
1d1t_A_3461d1t   A348359HVLPFKKISEGFEEEEGGGHHHHHbbbxaaaaaaaa
1dqs_A_381dqs   A4152LVTDTNIGSIYTEEEETTTHHHHHbbbbaaaaaaaa
1e19_A_2911e19   A293304IIAHLEKAVEALEEEEGGGHHHHHbbbxaaaaaaaa
1e3i_A_3481e3i   A350361HALPFESINDAIEEEEGGGHHHHHbbbxaaaaaaaa
1ezv_B_2371ezv   B243254IPVNKASLAQYEEEE-SSTHHHHHbwbxaaaaaaaa
1ezv_B_871ezv   B91102ATFLKDDLPYYVEEEEGGGHHHHHbbbxaaaaaaaa
1f4l_A_2881f4l   A291302HFIGKDIVYFHSEEEEGGGHHHHHbxbxaaaaaaaa
1g5h_D_2051g5h   D215226WFTPTRTSSQWLEEE-GGGHHHHHbbbxaaaaaaaa
1h3f_A_1901h3f   A191202EMGGTDQRFNLLEEEEGGGHHHHHbxbxaaaaaaaa
1h4v_B_4041h4v   B405416VRLSREEVPGYLEEEEGGGHHHHHbbbxaaaaaaaa
1iib_A_341iib   A3748EAFPETLAGEKGEEEEGGGHHHHHbbbxaaaaaaaa
1j1u_A_1661j1u   A167178AVGGMEQRKIHMEEEEGGGHHHHHbbbxaaaaaaaa
1knw_A_1661knw   A166175..IWYTDLPAAL..EEGGGHHHHH..xpaaaaaaaa
1l0l_A_951l0l   A99110IKALSKDLPKAVEEEEGGGHHHHHbxbpaaaaaaaa
1l0l_B_1051l0l   B109120VECLRDDVDILMEEEEGGGHHHHHbbbxaaaaaaaa
1l3s_A_8311l3s   A834845LEAPKEEMERLCEEEEGGGHHHHHbbbwaaaaaaaa
1lar_A_15891lar   A15891598..VPARNLYAHI..EEGGGHHHHH..bxaaaaaaaa
1m6h_A_3451m6h   A347358HNLSFDEINKAFEEEEGGGHHHHHbbbxaaaaaaaa
1m6j_A_401m6j   A4455VGVPFIYIPKVQEEE-GGGHHHHHbxbwaaaaaaaa
1n3l_A_1811n3l   A182193QFGGIDQRKIFTEEEEGGGHHHHHbbbxaaaaaaaa
1n8k_A_3461n8k   A348359HVLPFEKINEGFEEEEGGGHHHHHbbbxaaaaaaaa
1nj1_A_3761nj1   A377388VTADLQGIEETLEEEETTTHHHHHbbbxaaaaaaaa
1nn4_A_31nn4   A617FGCDHVGFILKHEEE-TTTHHHHHbbbxaaaaaaaa
1nnj_A_1131nnj   A115126ELISTDQVLPYFEEEEGGGHHHHHbbbxaaaaaaaa
1pie_A_3531pie   A356367ALVAHDNVSAFREEEEGGGHHHHHbbbpaaaaaaaa
1qor_A_3011qor   A301311.KYPLKDAQRAH.EEEGGGHHHHH.bbxaaaaaaaa
1rpm_A_8801rpm   A880889..IRVADLLQHI..EETTTHHHHH..bxaaaaaaaa
1ukf_A_2311ukf   A233244FQSSRSAAPQLIEEEETTTHHHHHbbbxaaaaaaaa
1ygh_A_2081ygh   A211222TYADNYAIGYFKEEE-GGGHHHHHbxxxaaaaaaaa
2kfn_A_8832kfn   A886897FEVHKDDVDAVAEEEETTTHHHHHbbbxaaaaaaaa
2shp_A_2212shp   A221230..INAAEIESRV..EEGGGHHHHH..bxaaaaaaaa
2ts1_*_1862ts1   -189200QIGGSDQWGNITEEEEGGGHHHHHbbbxaaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1b93_A_131b93   A     FMTFORMIC ACID L - 16
1b93_A_131b93   A     FMTFORMIC ACID V - 17
1b93_A_131b93   A     FMTFORMIC ACID A - 18
1b93_A_131b93   A     FMTFORMIC ACID H - 19
1b93_A_131b93   A     FMTFORMIC ACID D - 20
1b93_A_131b93   A     FMTFORMIC ACID K - 23
1b93_A_131b93   A     FMTFORMIC ACID L - 26
1cdo_A_3461cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE M - 362
1cf2_O_501cf2   O     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE A - 53
1cf2_O_501cf2   O     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE F - 61
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE L - 158
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE M - 159
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE C - 160
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE E - 161
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE A - 163
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE L - 164
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE F - 167
1cjw_A_1551cjw   A     COTCOA-S-ACETYL TRYPTAMINE Y - 168
1cl1_A_2211cl1   A     LLP2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE) G - 221
1d1t_A_3461d1t   A     ZNZINC ION E - 357
1d1t_A_3461d1t   A     ZNZINC ION E - 360
1d1t_A_3461d1t   A     ZNZINC ION L - 361
1d1t_A_3461d1t   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 362
1dqs_A_381dqs   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE D - 44
1dqs_A_381dqs   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 46
1dqs_A_381dqs   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 47
1dqs_A_381dqs   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 50
1dqs_A_381dqs   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE Y - 51
1e3i_A_3481e3i   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE M - 364
1f4l_A_2881f4l   A     METMETHIONINE I - 293
1f4l_A_2881f4l   A     METMETHIONINE I - 297
1f4l_A_2881f4l   A     METMETHIONINE H - 301
1g5h_D_2051g5h   D     GOLGLYCEROL E - 207
1g5h_D_2051g5h   D     GOLGLYCEROL K - 208
1g5h_D_2051g5h   D     GOLGLYCEROL T - 209
1g5h_D_2051g5h   D     MSESELENOMETHIONINE L - 213
1g5h_D_2051g5h   D     MSESELENOMETHIONINE W - 229
1g5h_D_2051g5h   D     MSESELENOMETHIONINE H - 232
1g5h_D_2051g5h   D     MSESELENOMETHIONINE R - 233
1g5h_D_2051g5h   D     MSESELENOMETHIONINE W - 236
1g5h_D_2051g5h   D     MSESELENOMETHIONINE R - 238
1h3f_A_1901h3f   A     TYBTYROSINAL E - 191
1h3f_A_1901h3f   A     TYBTYROSINAL Q - 197
1h3f_A_1901h3f   A     TYBTYROSINAL N - 200
1j1u_A_1661j1u   A     TYRTYROSINE Q - 173
1j1u_A_1661j1u   A     TYRTYROSINE I - 176
1l3s_A_8311l3s   A     MGMAGNESIUM ION E - 831
1m6h_A_3451m6h   A     PO4PHOSPHATE ION M - 361
1n8k_A_3461n8k   A     NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM) L - 362
1nnj_A_1131nnj   A     CRYPROPANE-1,2,3-TRIOL T - 113
1nnj_A_1131nnj   A     CRYPROPANE-1,2,3-TRIOL E - 115
1nnj_A_1131nnj   A     CRYPROPANE-1,2,3-TRIOL Y - 125
1nnj_A_1131nnj   A     CRYPROPANE-1,2,3-TRIOL K - 129
1qor_A_3011qor   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 314
1qor_A_3011qor   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE E - 315
2kfn_A_8832kfn   A     ZNZINC ION H - 901
2kfn_A_8832kfn   A     ZNZINC ION E - 905
2kfn_A_8832kfn   A     ZNZINC ION N - 906
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1ati_A_2341ati   A SA1THESE RESIDUES ARE FOUND TO BE RESPONSIBLE FOR ON THE BASIS OF MODELLING GLYCYL-AMP INTO THE ACTIVE SITE OF GLYCYL-TRNA SYNTHETASE.F - 235
1ati_A_2341ati   A SA1THESE RESIDUES ARE FOUND TO BE RESPONSIBLE FOR ON THE BASIS OF MODELLING GLYCYL-AMP INTO THE ACTIVE SITE OF GLYCYL-TRNA SYNTHETASE.Q - 237
1ati_A_2341ati   A SA1THESE RESIDUES ARE FOUND TO BE RESPONSIBLE FOR ON THE BASIS OF MODELLING GLYCYL-AMP INTO THE ACTIVE SITE OF GLYCYL-TRNA SYNTHETASE.E - 239
1ati_A_2341ati   A SA1THESE RESIDUES ARE FOUND TO BE RESPONSIBLE FOR ON THE BASIS OF MODELLING GLYCYL-AMP INTO THE ACTIVE SITE OF GLYCYL-TRNA SYNTHETASE.E - 241
1h3f_A_1901h3f   A AC6TYB BINDING SITE FOR CHAIN AE - 191
1h3f_A_1901h3f   A AC6TYB BINDING SITE FOR CHAIN AQ - 197
1h3f_A_1901h3f   A AC6TYB BINDING SITE FOR CHAIN AN - 200

Clusters included in this Subclass
CLUSTER: EH.2.23
CLUSTER: EH.3.14
CLUSTER: EH.3.58
CLUSTER: EH.4.5
CLUSTER: EH.4.50
CLUSTER: EH.4.73
CLUSTER: EH.5.119