ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 5.3.1

Subclass Accession number: 710
Subclass: 5.3.1

PSSM

Type: HA beta-beta hairpin
DB: ArchDB40

Image coordinates:

Rasmol PDB

Jmol PDB

Consensus coordinates:

Rasmol PDB

Jmol PDB

Conserved Annotation
EC : 2.7.1 (>50 %) 2.7.1.37
SCOP : 48726 (>75 %) 48727 (>75 %) 56111 (>50 %) 56112 (>50 %) 88854 (>50 %)

Number of loops: 24

Average sequence ID (%) : 13.8 +/- 16.6
Average RMSD (Å) : 0.475 +/- 0.162

Consensus geometry

d (Å): 5

delta (°): 90-135

theta (°): 90-135

rho (°): 45-90

Consensus Sequence:	XXpXpXXhh
(φψ)-conformation:	bbpaalppb

Pattern:	x	x	[dknqst]	[adkqrst]	[dehknqst]	[dgnq]	x	[cfilmpvwy]	[afgilvwy]
Conservation:	-1.011	-0.436	1.788	-0.130	1.198	0.730	-0.574	-0.946	-0.619

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1a8d_*_391	1a8d	-	394	402	LYDDKNASL	EE-SSS-EE	xbxaavxxa
1ahs_A_194	1ahs	A	194	202	FCDPQGASL	EE-TTS-EE	bbxaavxxb
1ece_A_12	1ece	A	13	21	ILDANNVPV	EE-TTS-EE	bbxaavxwb
1f61_A_249	1f61	A	252	260	ERTREGFYR	EE-TTS-EE	xbxaavxxx
1fp3_A_361	1fp3	A	361	369	YLNREGKVA	EE-TTS-EE	bbxaavxxa
1goi_A_46	1goi	A	53	61	DINSNLECA	EE-TTSSEE	bbxaavbxb
1hiz_A_332	1hiz	A	333	341	YYDANGNVV	EE-TTS-EE	xbxaavbpb
1hzt_A_35	1hzt	A	39	47	LFNAKGQLL	EE-TT--EE	bbxaavxxx
1i2k_A_161	1i2k	A	164	172	VLDSEGWVT	EEBTTSBEE	bbxaavxpa
1jke_A_55	1jke	A	55	63	FSDAEGKMN	EE-TTS-EE	bxxaagbxa
1jvw_A_88	1jvw	A	94	102	GRLRDGTVF	EE-TTS-EE	bbxaavpxa
1jy5_A_174	1jy5	A	181	189	CFDKTLQLQ	EE-TTS-EE	bbxaavxpb
1k5n_B_55	1k5n	B	55	63	SFSKDWSFY	EE-TTS-EE	bbxaavxxb
1khb_A_383	1khb	A	383	391	ITSWKNKEW	EE-TTSSEE	bbxaavbxb
1ly2_A_109	1ly2	A	111	119	WCQANNMWG	EE-TTSSEE	bxxaavbxb
1oac_A_585	1oac	A	593	601	KENRMGNPV	EE-TTS-EE	bbxaavbpx
1oe4_A_179	1oe4	A	180	188	FMNHSGKNL	EE-TT--EE	bbxaavxxb
1p3c_A_174	1p3c	A	175	183	MLDQNQQIV	EE-TTS-EE	xbxaavxxa
1q1u_A_11	1q1u	A	15	23	LFSQQGYFL	EEETTTEEE	bxxaavbxx
1qme_A_79	1qme	A	79	87	IYDRNGVPI	EE-TTS-EE	bbxaavxwa
1rku_A_109	1rku	A	115	123	EIDDSDRVV	EE-TTS-EE	bbxaavxxa
1rzt_A_537	1rzt	A	537	545	VRNTHGCKV	EE-TT--EE	xbbaalbpa
2nap_A_250	2nap	A	253	261	FMDAEGKPS	EE-TTS-EE	bbxaavxpb
2plc_*_80	2plc	-	84	92	RAKDNLNIY	EE-TTSEEE	bbbaavbxb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1a8d_*_391	1a8d	*	AUGOLD ION	Q - 391
1a8d_*_391	1a8d	*	AUGOLD ION	L - 404
1goi_A_46	1goi	A	GOLGLYCEROL	F - 51
1i2k_A_161	1i2k	A	PLPPYRIDOXAL-5'-PHOSPHATE	E - 173
1k5n_B_55	1k5n	B	GOLGLYCEROL	S - 55
1k5n_B_55	1k5n	B	GOLGLYCEROL	F - 56
1k5n_B_55	1k5n	B	GOLGLYCEROL	S - 57
1k5n_B_55	1k5n	B	GOLGLYCEROL	K - 58
1k5n_B_55	1k5n	B	GOLGLYCEROL	W - 60
1k5n_B_55	1k5n	B	GOLGLYCEROL	Y - 63
1oac_A_585	1oac	A	CACALCIUM ION	L - 588
1rku_A_109	1rku	A	EDO1,2-ETHANEDIOL	L - 109
1rku_A_109	1rku	A	EDO1,2-ETHANEDIOL	K - 113

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
2plc_*_80	2plc	*	CICINOSITOL BINDING SITE.	H - 93

Clusters included in this Subclass

CLUSTER: HA.4.36

CLUSTER: HA.4.68

CLUSTER: HA.5.30

CLUSTER: HA.6.18