Information on SUBCLASS 2.1.3 |
Subclass Accession number: 7125
Subclass: 2.1.3 Type: EH beta-alpha DB: ArchDB-EC Image coordinates: Consensus coordinates: |
Number of loops: 80 Average sequence ID (%) : 10.3 +/- 13.4 Average RMSD (Å) : 0.573 +/- 0.201 Consensus geometry
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Consensus Sequence: | XXXpXp |
(φψ)-conformation: | bbabaa |
Pattern: | x | [afgiklmtv] | x | [acdgnpstv] | x | [cdehnqrst] | x | [adegknqrst] | x | x |
Conservation: | 0.572 | 0.783 | -1.419 | -0.821 | -1.299 | 1.605 | -0.444 | 0.941 | -0.059 | 0.140 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1ad3_A_341 | 1ad3 | A | 341 | 350 | IVCVRSLEEA | EEE-SSHHHH | bbbbabaaaa |
1ajs_A_267 | 1ajs | A | 271 | 280 | TVVAKEPDSI | EEE-SSHHHH | xbbbabaaaa |
1ars_*_267 | 1ars | - | 271 | 280 | TLVAADSETV | EEE-SSTTHH | bbbbabaaaa |
1bfd_*_40 | 1bfd | - | 41 | 50 | YILALQEACV | EEE-SSHHHH | bbxbabaaaa |
1bg6_*_29 | 1bg6 | - | 31 | 40 | LAWDIDAQRI | EEE-S-HHHH | bbbbaxaaaa |
1bjt_*_573 | 1bjt | - | 575 | 584 | TIAFYNMPDY | EEESSHHHHH | bxbbabaaaa |
1bt4_A_299 | 1bt4 | A | 301 | 310 | TFRLASEELE | EEE-SSHHHH | bbbbabaaaa |
1c25_*_399 | 1c25 | - | 399 | 407 | .VNLHMEEEV | .EE--SHHHH | .bxbabaaaa |
1dcf_A_9 | 1dcf | A | 11 | 20 | LVMDENGVSR | EEE-S-HHHH | bbbbaxaaaa |
1dlj_A_362 | 1dlj | A | 362 | 370 | .VLVNDLENF | .EE---HHHH | .bxbaxaaaa |
1dnp_A_72 | 1dnp | A | 74 | 83 | FREVDDFVAS | EEE-SSHHHH | xbbbabaaaa |
1dqa_A_593 | 1dqa | A | 593 | 602 | VVRLPRACDS | EEE-SSHHHH | bbbbabaaaa |
1em8_A_39 | 1em8 | A | 40 | 49 | LIACEDEKQA | EEE-SSHHHH | bbxxabaaaa |
1euc_B_375 | 1euc | B | 375 | 384 | ITSAVDLEDA | EEE-SSHHHH | bbxxabaaaa |
1ez4_A_47 | 1ez4 | A | 49 | 58 | VIVDVVKDRT | EEE-SSHHHH | xbbbaxaaaa |
1f0y_A_40 | 1f0y | A | 42 | 51 | VLVDQTEDIL | EEE-S-HHHH | bxbbabaaaa |
1f0y_A_88 | 1f0y | A | 88 | 97 | IATSTDAASV | EEEES-HHHH | bxbbabaaaa |
1ffw_A_8 | 1ffw | A | 9 | 18 | LVVDDFSTMR | EEE-SSHHHH | bxbbabaaaa |
1fl2_A_342 | 1fl2 | A | 342 | 349 | ..VTYCPHCD | ..EES-HHHH | ..xbabaaaa |
1gdh_A_192 | 1gdh | A | 192 | 200 | .TFHDSLDSL | .EE-SSHHHH | .xxbabaaaa |
1gtk_A_124 | 1gtk | A | 124 | 133 | IVGTSSLRRQ | EEE---HHHH | bbxbaxaaaa |
1gvf_A_20 | 1gvf | A | 22 | 31 | AFNIHNAETI | EEE--SHHHH | bbxbabaaaa |
1h10_A_82 | 1h10 | A | 87 | 96 | TFHVETPEER | EEE-SSHHHH | bbbbabaaaa |
1hei_B_364 | 1hei | B | 365 | 374 | LIFCHSKKKC | EEE-S-HHHH | bbbbabaaaa |
1hnn_A_96 | 1hnn | A | 98 | 107 | TMTDFLEVNR | EEE-S-HHHH | bbbbaxaaaa |
1hyh_A_48 | 1hyh | A | 50 | 59 | VFIDANEAKV | EEE-SSHHHH | bbbbaxaaaa |
1i0z_A_47 | 1i0z | A | 49 | 58 | ALVDVLEDKL | EEE-S-HHHH | bbbbaxaaaa |
1ih7_A_57 | 1ih7 | A | 59 | 68 | RKLFANMRDA | EEE-SSHHHH | xbxxabaaaa |
1itu_A_100 | 1itu | A | 100 | 109 | FLYVTSSAGI | EEE--SHHHH | xbxbabaaaa |
1j96_A_266 | 1j96 | A | 268 | 277 | LAKSYNEQRI | EEE--SHHHH | xbxbabaaaa |
1jqe_A_82 | 1jqe | A | 86 | 95 | EVVEPSAEQI | EEE---HHHH | bbbbaxaaaa |
1jqk_A_612 | 1jqk | A | 613 | 622 | FIVDTDPKSA | EEE-S-HHHH | xbxbabaaaa |
1jsc_A_132 | 1jsc | A | 133 | 142 | FVLPKHEQGA | EE--SSHHHH | xxbxabaaaa |
1kae_A_306 | 1kae | A | 307 | 316 | LIVTKDLAQC | EEE-SSHHHH | bbbbabaaaa |
1kw3_B_207 | 1kw3 | B | 211 | 220 | MLQANTIDDV | EEEBSSHHHH | bbbxabaaaa |
1l3i_A_57 | 1l3i | A | 59 | 68 | YAIDRNPEAI | EEE-S-HHHH | bbbbaxaaaa |
1lgt_A_208 | 1lgt | A | 212 | 221 | MLEVASLDDV | EEEBS-HHHH | bbbbabaaaa |
1lld_A_34 | 1lld | A | 36 | 45 | VLEDIAKERV | EEE-SSHHHH | bbbbaxaaaa |
1luc_B_225 | 1luc | B | 230 | 239 | VNQNVDGEAA | EEE-SSHHHH | bbbbaxaaaa |
1m6y_A_50 | 1m6y | A | 52 | 61 | IGIDVDSEVL | EEEES-HHHH | bbbbaxaagg |
1mai_*_108 | 1mai | - | 109 | 118 | DLIAPSPADA | EEE-SSHHHH | bbbxabaaaa |
1mpy_A_211 | 1mpy | A | 216 | 225 | SFHLETWEDL | EEE-S-HHHH | bbxbabaaaa |
1mum_A_20 | 1mum | A | 22 | 31 | IVGTINANHA | EEE-SSHHHH | bbxbabaaaa |
1mv8_A_25 | 1mv8 | A | 27 | 36 | IGVDVSSTKI | EEE-S-HHHH | bxbbaxaaaa |
1mx3_A_218 | 1mx3 | A | 218 | 226 | .QRVSTLQDL | .EE-SSHHHH | .xbbabaaaa |
1nj1_A_411 | 1nj1 | A | 411 | 420 | IREAETLEEA | EEE-SSHHHH | bbxbabaaaa |
1nyr_A_213 | 1nyr | A | 219 | 228 | GTAFFDKKEL | EEEESSHHHH | bbbbabaaaa |
1o17_A_187 | 1o17 | A | 189 | 198 | LMGVFSKDHL | EEE-SSHHHH | bbxbabaaaa |
1oao_A_631 | 1oao | A | 632 | 641 | FIFEMDPQVA | EEE-SSHHHH | xbxbaxaaaa |
1oao_C_292 | 1oao | C | 292 | 301 | FFSVEDYDKI | EEE---HHHH | bbxbaxaaaa |
1obb_A_34 | 1obb | A | 36 | 45 | TLMDIDEERL | EEE-S-HHHH | bbbbaxaaaa |
1ohv_A_411 | 1ohv | A | 413 | 422 | SFDTPDESIR | EEE-SSHHHH | bbxbabaaaa |
1ovm_A_45 | 1ovm | A | 46 | 55 | WVGCANELNA | EEE-SSHHHH | xbxbabaaaa |
1oyw_A_239 | 1oyw | A | 240 | 249 | IIYCNSRAKV | EEE-SSHHHH | bbxbabaaaa |
1ozh_A_50 | 1ozh | A | 51 | 60 | IIPVRHEANA | EEE-SSHHHH | xbwbabaaaa |
1pgj_A_27 | 1pgj | A | 28 | 37 | AVFNRTYSKS | EEE-SSHHHH | xbbbaxaaaa |
1pgj_A_53 | 1pgj | A | 53 | 62 | LKAFETMEAF | EEE-S-HHHH | bxxbabaaaa |
1pk9_A_15 | 1pk9 | A | 16 | 25 | VLMPGDPLRA | EEE-SSTHHH | bxbxaxaaaa |
1pox_A_52 | 1pox | A | 53 | 62 | YIQVRHEEVG | EEE-SSHHHH | xbxxabaaaa |
1psd_A_192 | 1psd | A | 192 | 200 | .TQVQHLSDL | .EE-S-HHHH | .bxxabaaaa |
1q0s_A_46 | 1q0s | A | 47 | 56 | LANDIQEPII | EEE-S-HHHH | bxbbaxaaaa |
1q6o_A_5 | 1q6o | A | 9 | 18 | ALDNQTMDSA | EE--SSHHHH | xxxbabaaaa |
1qam_A_54 | 1qam | A | 56 | 65 | TAIEIDHKLC | EEE-S-HHHH | bxbbaxaaaa |
1qht_A_181 | 1qht | A | 181 | 190 | VDVVSTEKEM | EEE-S-HHHH | xbxbabaaaa |
1qht_A_78 | 1qht | A | 84 | 93 | KLYFNHPQDV | EEE-S-TTHH | xxxbabaaaa |
1qip_A_33 | 1qip | A | 35 | 44 | MLRVKDPKKS | EEE-S-HHHH | bbxbabaaaa |
1qwg_A_202 | 1qwg | A | 203 | 212 | IFEAPQKSQQ | EEE--SHHHH | bxxbaxaaaa |
1srr_A_5 | 1srr | A | 7 | 16 | LIVDDQSGIR | EEE-S-HHHH | bbbbabaaaa |
1tgo_A_181 | 1tgo | A | 181 | 190 | VDVVSTEKEM | EEE-SSHHHH | bbxbabaaaa |
1tgo_A_78 | 1tgo | A | 84 | 93 | KLYFTHPQDV | EEE-S-TTHH | xxxbabaaaa |
1trb_*_132 | 1trb | - | 132 | 139 | ..VSACATSD | ..EES-HHHH | ..bbabaaaa |
1uek_A_237 | 1uek | A | 238 | 247 | FGLAEGPDHA | EEE-SSHHHH | bbxbabaaaa |
1zpd_A_43 | 1zpd | A | 44 | 53 | QVYCCNELNC | EEE-SSHHHH | xbbbabaaaa |
2ay1_A_267 | 2ay1 | A | 271 | 280 | LALCADAATR | EEE-SSHHHH | bbxbabaaaa |
2cst_A_267 | 2cst | A | 271 | 280 | SVVGKDEDNV | EEE-SSHHHH | xbbbabaaaa |
2pgd_*_52 | 2pgd | - | 52 | 60 | .LGAHSLEEM | .EE-SSHHHH | .bbbabaaaa |
4uag_A_384 | 4uag | A | 384 | 393 | AEQTETMEQA | EEE-SSHHHH | bbbbabaaaa |
6mht_A_34 | 6mht | A | 37 | 46 | YSNEWDKYAQ | EEE---HHHH | bbbbaxaaaa |
7aat_A_267 | 7aat | A | 271 | 280 | TVICRDAEEA | EEE-SSHHHH | bbxbabaaaa |
9ldt_A_48 | 9ldt | A | 50 | 59 | ALVDVMEDKL | EEE-S-HHHH | bbbbaxaaaa |
PDB ligands within a cut-off distance of 6 Å in this subclass |
PDB Site Annotated loops in this subclass |
Loop | PDB | Chain | Site | Residue |
1gtk_A_124 | 1gtk | A | AC1DPM BINDING SITE FOR CHAIN A | T - 127 |
1gtk_A_124 | 1gtk | A | AC1DPM BINDING SITE FOR CHAIN A | R - 132 |
1obb_A_34 | 1obb | A | AC1NAD BINDING SITE FOR CHAIN A | M - 38 |
1obb_A_34 | 1obb | A | AC1NAD BINDING SITE FOR CHAIN A | D - 39 |
1obb_A_34 | 1obb | A | AC1NAD BINDING SITE FOR CHAIN A | I - 40 |
1obb_A_34 | 1obb | A | AC1NAD BINDING SITE FOR CHAIN A | R - 44 |
1qip_A_33 | 1qip | A | ZN1ZINC BINDING SITE AT DIMER INTERFACE. | Q - 33 |
1qip_A_33 | 1qip | A | GH1BINDING SITE FOR GSH MOIETY - SUBSTRATE BINDING SITE IS FORMED BY ZN2 HYD2 AND GSH2. | R - 37 |
Clusters included in this Subclass |
CLUSTER: EH.2.4 |
CLUSTER: EH.3.2 |
CLUSTER: EH.4.0 |