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Information on SUBCLASS 2.1.7
Subclass Accession number: 7129
Subclass: 2.1.7 PSSM
Type: EH beta-alpha
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 34

Average sequence ID (%) : 9.8 +/- 13.6
Average RMSD (Å) : 0.641 +/- 0.212

Consensus geometry
d (Å): 11 delta (°): 45-90 theta (°): 135-180 rho (°): 180-225
Consensus Sequence: XXXpXX
(φψ)-conformation: bbabaa
Pattern: x[afilmvwy][adegknqrst]xx[degnqst]xxx[agilv]
Conservation:0.1980.625-0.108-0.436-0.9230.956-1.049-0.778-0.6122.126
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1b6r_A_3141b6r   A319328NLTDSDTSRLEEE-S-HHHHbbbbaxaaaa
1bif_*_2971bif   -298307VFTSQMKRTIEEE-SSHHHHbbbxaxaaaa
1c30_A_7271c30   A727734..IVYDEADL..EE-SHHHH..bxabaaaa
1cfr_*_2651cfr   -266275IFKINSVLDVEEE-SSHHHHbbxbabaaaa
1d9e_D_40921d9e   D40934102ITDVHEPSQAEEE--SHHHHbbxbabaaaa
1dii_A_601dii   A6170AVTATTVEQVEEE--SHHHHbbbxabaaaa
1efy_A_8951efy   A895904IYFADMVSKSEEEBSSHHHHbxbbabaaaa
1eix_A_171eix   A2029ALDYHNRDDAEE--SSHHHHxxbbabaaaa
1ex7_A_1641ex7   A165174VIVNDDLDKAEEE-SSHHHHbbxxabaaaa
1f07_A_1481f07   A149158YMGAQGPMMLEEE--SHHHHbbxbabaaaa
1f0k_A_81f0k   A1120VMAGGTGGHVEE--SSHHHHbbbxabaaaa
1gs0_A_4371gs0   A437446IYFADMSSKSEEEBS-HHHHbxbbabaaaa
1gtz_A_511gtz   A5362FRQSNHEGELEEE-S-HHHHbbbbabaaaa
1gx3_A_2331gx3   A236245HIRFDSAAQVEEE-SSHHHHbbbxabaaaa
1h05_A_461h05   A4958VRQSDSEAQLEEE-S-HHHHbbbbaxaaaa
1ihu_A_4911ihu   A495504LVTLPETTPVEEE-SSHHHHxxbbabaaaa
1ile_*_4681ile   -468476.EAIGSFQEL.EE--SHHHH.bbxabaaaa
1itx_A_2471itx   A250259IASGASATYAEEE--SHHHHbbbxaxaaaa
1k87_A_4801k87   A483492QFATHNAHTLEEE---HHHHbxxbaxaaaa
1khb_A_4441khb   A444453VYEALSWQHGEEE-SSHHHHbbbxabaaaa
1li4_A_2381li4   A240249IITEIDPINAEEE-S-HHHHbbbbaxaaaa
1lvg_A_1671lvg   A168177VIINDDLDKAEEE-SSHHHHbbxxaxaaaa
1m3u_A_191m3u   A2130TITAYDYSFAEEE--SHHHHbbxbabaaaa
1mai_*_1081mai   -109118DLIAPSPADAEEE-SSHHHHbbbxabaaaa
1mhy_D_4441mhy   D445454KHSLTDDWGEEEEE-SHHHHxbbbabaaaa
1mve_A_1351mve   A140149LWSSESAAWVEEEBS-HHHHbbbxaxaaaa
1omw_A_6291omw   A631640VLQCDSDPELEEE-SSHHHHbbbbabaaaa
1pyt_A_111pyt   A1423RITAADEAEVEEE-SSHHHHbxbxabaaaa
1q0s_A_461q0s   A4756LANDIQEPIIEEE-S-HHHHbxbbaxaaaa
1q6o_A_51q6o   A918ALDNQTMDSAEE--SSHHHHxxxbabaaaa
1qb0_A_4411qb0   A441449.VNLPLERDA.EE--SHHHH.bxbaxaaaa
1qhf_A_511qhf   A5261LYTSKLSRAIEEE-SSHHHHbbbxabaaaa
1ses_A_2201ses   A220229LYLTGTAEVVEEE-SSTHHHbbxxabaaaa
1uqr_A_451uqr   A4857YFQANGEESLEEE-SSHHHHbbbbabaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1bif_*_2971bif   *     GOLGLYCEROL F - 299
1bif_*_2971bif   *     PO4PHOSPHATE ION M - 303
1bif_*_2971bif   *     PO4PHOSPHATE ION R - 305
1efy_A_8951efy   A     BZC2-(3'-METHOXYPHENYL) BENZIMIDAZOLE-4-CARBOXAMIDE Y - 896
1efy_A_8951efy   A     BZC2-(3'-METHOXYPHENYL) BENZIMIDAZOLE-4-CARBOXAMIDE F - 897
1efy_A_8951efy   A     BZC2-(3'-METHOXYPHENYL) BENZIMIDAZOLE-4-CARBOXAMIDE A - 898
1efy_A_8951efy   A     BZC2-(3'-METHOXYPHENYL) BENZIMIDAZOLE-4-CARBOXAMIDE K - 903
1efy_A_8951efy   A     BZC2-(3'-METHOXYPHENYL) BENZIMIDAZOLE-4-CARBOXAMIDE S - 904
1efy_A_8951efy   A     BZC2-(3'-METHOXYPHENYL) BENZIMIDAZOLE-4-CARBOXAMIDE A - 905
1eix_A_171eix   A     BMQ1-(5'-PHOSPHO-BETA-D-RIBOFURANOSYL)BARBITURIC ACID A - 20
1eix_A_171eix   A     BMQ1-(5'-PHOSPHO-BETA-D-RIBOFURANOSYL)BARBITURIC ACID D - 22
1f07_A_1481f07   A     MPD2-METHYL-2,4-PENTANEDIOL A - 152
1f07_A_1481f07   A     MPD2-METHYL-2,4-PENTANEDIOL Q - 153
1f07_A_1481f07   A     MPD2-METHYL-2,4-PENTANEDIOL G - 154
1f07_A_1481f07   A     MPD2-METHYL-2,4-PENTANEDIOL P - 155
1f07_A_1481f07   A     MPD2-METHYL-2,4-PENTANEDIOL L - 158
1gtz_A_511gtz   A     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL E - 59
1ihu_A_4911ihu   A     ADPADENOSINE-5'-DIPHOSPHATE V - 496
1ihu_A_4911ihu   A     TASTRIHYDROXYARSENITE(III) P - 499
1ihu_A_4911ihu   A     ADPADENOSINE-5'-DIPHOSPHATE E - 500
1ihu_A_4911ihu   A     TASTRIHYDROXYARSENITE(III) E - 500
1ihu_A_4911ihu   A     ADPADENOSINE-5'-DIPHOSPHATE T - 501
1ihu_A_4911ihu   A     MGMAGNESIUM ION T - 502
1ihu_A_4911ihu   A     ADPADENOSINE-5'-DIPHOSPHATE T - 502
1ihu_A_4911ihu   A     ADPADENOSINE-5'-DIPHOSPHATE P - 503
1itx_A_2471itx   A     GOLGLYCEROL A - 251
1itx_A_2471itx   A     GOLGLYCEROL S - 252
1itx_A_2471itx   A     GOLGLYCEROL G - 253
1itx_A_2471itx   A     GOLGLYCEROL A - 254
1itx_A_2471itx   A     GOLGLYCEROL S - 255
1k87_A_4801k87   A     FADFLAVIN-ADENINE DINUCLEOTIDE A - 485
1k87_A_4801k87   A     FADFLAVIN-ADENINE DINUCLEOTIDE T - 486
1k87_A_4801k87   A     FADFLAVIN-ADENINE DINUCLEOTIDE H - 487
1k87_A_4801k87   A     FADFLAVIN-ADENINE DINUCLEOTIDE N - 488
1k87_A_4801k87   A     FADFLAVIN-ADENINE DINUCLEOTIDE T - 491
1k87_A_4801k87   A     1PEPENTAETHYLENE GLYCOL Q - 497
1k87_A_4801k87   A     1PEPENTAETHYLENE GLYCOL L - 498
1khb_A_4441khb   A     EDO1,2-ETHANEDIOL E - 446
1khb_A_4441khb   A     EDO1,2-ETHANEDIOL A - 447
1khb_A_4441khb   A     EDO1,2-ETHANEDIOL L - 448
1khb_A_4441khb   A     EDO1,2-ETHANEDIOL S - 449
1khb_A_4441khb   A     EDO1,2-ETHANEDIOL W - 450
1khb_A_4441khb   A     EDO1,2-ETHANEDIOL Q - 451
1khb_A_4441khb   A     EDO1,2-ETHANEDIOL G - 453
1li4_A_2381li4   A     IPAISOPROPYL ALCOHOL R - 238
1li4_A_2381li4   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE T - 242
1li4_A_2381li4   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE E - 243
1li4_A_2381li4   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 244
1li4_A_2381li4   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE D - 245
1li4_A_2381li4   A     NAHNICOTINAMIDE-ADENINE-DINUCLEOTIDE N - 248
1lvg_A_1671lvg   A     ADPADENOSINE-5'-DIPHOSPHATE N - 171
1lvg_A_1671lvg   A     ADPADENOSINE-5'-DIPHOSPHATE D - 172
1lvg_A_1671lvg   A     ADPADENOSINE-5'-DIPHOSPHATE D - 173
1lvg_A_1671lvg   A     ADPADENOSINE-5'-DIPHOSPHATE L - 174
1lvg_A_1671lvg   A     ADPADENOSINE-5'-DIPHOSPHATE D - 175
1m3u_A_191m3u   A     KPLKETOPANTOATE T - 23
1m3u_A_191m3u   A     KPLKETOPANTOATE Y - 25
1mai_*_1081mai   *     I3PD-MYO-INOSITOL-1,4,5-TRIPHOSPHATE L - 108
1mve_A_1351mve   A     MSESELENOMETHIONINE L - 136
1mve_A_1351mve   A     CACALCIUM ION L - 136
1mve_A_1351mve   A     MSESELENOMETHIONINE R - 137
1mve_A_1351mve   A     CACALCIUM ION R - 137
1mve_A_1351mve   A     MSESELENOMETHIONINE F - 138
1mve_A_1351mve   A     CACALCIUM ION F - 138
1mve_A_1351mve   A     MSESELENOMETHIONINE N - 139
1mve_A_1351mve   A     CACALCIUM ION N - 139
1q0s_A_461q0s   A     SAHS-ADENOSYL-L-HOMOCYSTEINE N - 49
1q0s_A_461q0s   A     SAHS-ADENOSYL-L-HOMOCYSTEINE D - 50
1q0s_A_461q0s   A     SAHS-ADENOSYL-L-HOMOCYSTEINE I - 51
1q0s_A_461q0s   A     SAHS-ADENOSYL-L-HOMOCYSTEINE Q - 52
1q0s_A_461q0s   A     SAHS-ADENOSYL-L-HOMOCYSTEINE I - 55
1q6o_A_51q6o   A     MGMAGNESIUM ION A - 9
1q6o_A_51q6o   A     LG6L-GULURONIC ACID 6-PHOSPHATE A - 9
1q6o_A_51q6o   A     LG6L-GULURONIC ACID 6-PHOSPHATE L - 10
1q6o_A_51q6o   A     MGMAGNESIUM ION D - 11
1q6o_A_51q6o   A     LG6L-GULURONIC ACID 6-PHOSPHATE D - 11
1qhf_A_511qhf   A     3PG3-PHOSPHOGLYCERIC ACID R - 59
1ses_A_2201ses   A     AHXSERYL-HYDROXAMATE-ADENOSINE MONOPHOSPHATE G - 224
1ses_A_2201ses   A     AHXSERYL-HYDROXAMATE-ADENOSINE MONOPHOSPHATE T - 225
1ses_A_2201ses   A     AHXSERYL-HYDROXAMATE-ADENOSINE MONOPHOSPHATE A - 226
1ses_A_2201ses   A     AHXSERYL-HYDROXAMATE-ADENOSINE MONOPHOSPHATE E - 227
1uqr_A_451uqr   A     TRS2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL E - 54
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gtz_A_511gtz   A TRATRS BINDING SITE FOR CHAIN AE - 59
1h05_A_461h05   A SO3SO4 BINDING SITE FOR CHAIN AR - 50
1h05_A_461h05   A SO2SO4 BINDING SITE FOR CHAIN AS - 54
1h05_A_461h05   A SO3SO4 BINDING SITE FOR CHAIN AW - 61
1h05_A_461h05   A SO3SO4 BINDING SITE FOR CHAIN AQ - 64
1uqr_A_451uqr   A AC1SO4 BINDING SITE FOR CHAIN AG - 53
1uqr_A_451uqr   A AC1SO4 BINDING SITE FOR CHAIN AE - 54
1uqr_A_451uqr   A AC1SO4 BINDING SITE FOR CHAIN AE - 55

Clusters included in this Subclass
CLUSTER: EH.2.19
CLUSTER: EH.3.25
CLUSTER: EH.3.36
CLUSTER: EH.3.50
CLUSTER: EH.4.201
CLUSTER: EH.4.7