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Information on SUBCLASS 2.1.12
Subclass Accession number: 7134
Subclass: 2.1.12 PSSM
Type: EH beta-alpha
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 13

Average sequence ID (%) : 14.0 +/- 15.5
Average RMSD (Å) : 0.569 +/- 0.202

Consensus geometry
d (Å): 13 delta (°): 0-45 theta (°): 135-180 rho (°): 180-225
Consensus Sequence: XhpphX
(φψ)-conformation: bbabaa
Pattern: x[hilv]x[gmpy][dgkqrst][DGNST][agiklv][adegknr][DEHQRS][AFILV]x[ADEQRST][afilvy]
Conservation:-0.6480.155-0.9390.368-0.8031.902-0.691-0.6571.4811.105-1.2410.440-0.471
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1afs_A_2661afs   A268280LIRSFNAKRIKELEE--S-HHHHHHHbbbbabaaaaaaa
1e8g_A_731e8g   A7486IVAPRNVADVQSIEE--SSHHHHHHHbbbpabaaaaaaa
1eix_A_171eix   A2032ALDYHNRDDALAFEE--SSHHHHHHHxxbbabaaaaaaa
1f0x_A_481f0x   A4961VVFPGSLLELWRVEE--SSHHHHHHHbbbxabaaaaaaa
1ffv_C_71ffv   C820YHAPKSVGEAVALEE--SSHHHHHHHbbbxabaaaaaaa
1fo8_A_3851fo8   A387399RVQYTGRDSFKAFEEE--SHHHHHHHbbxbabaaaaaaa
1fvg_A_1581fvg   A158170AIYPTSAEHVGAAEE--SSHHHHHHHbbbxabaaaaaaa
1g19_A_1161g19   A117129VSQPDTGEQALEIEE--SSHHHHHHHbbbxabaaaaaaa
1g71_A_481g71   A5062KNQYSDIRDLEDYEE--SSHHHHHHHlxbbabaaaaaaa
1gqn_A_1681gqn   A172184AVMPQSKHDVLTLEE--SSHHHHHHHbbxxabaaaaaaa
1gqn_A_171gqn   A2133SLMGRDINSVKAEEE--SSHHHHHHHbbbbabaaaaaaa
1gve_A_2801gve   A282294ILGMSSLEQLEQNEE--SSHHHHHHHxxbbabaaaaaaa
1n62_C_71n62   C820YHRPKSIADAVALEE--SSHHHHHHHbbbxabaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1afs_A_2661afs   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 268
1afs_A_2661afs   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE I - 269
1afs_A_2661afs   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE R - 270
1afs_A_2661afs   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 271
1afs_A_2661afs   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE F - 272
1afs_A_2661afs   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE N - 273
1afs_A_2661afs   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE R - 276
1afs_A_2661afs   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE I - 277
1afs_A_2661afs   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE E - 279
1afs_A_2661afs   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 280
1eix_A_171eix   A     BMQ1-(5'-PHOSPHO-BETA-D-RIBOFURANOSYL)BARBITURIC ACID A - 20
1eix_A_171eix   A     BMQ1-(5'-PHOSPHO-BETA-D-RIBOFURANOSYL)BARBITURIC ACID D - 22
1f0x_A_481f0x   A     FADFLAVIN-ADENINE DINUCLEOTIDE L - 58
1fvg_A_1581fvg   A     MSESELENOMETHIONINE A - 158
1fvg_A_1581fvg   A     MSESELENOMETHIONINE Y - 160
1fvg_A_1581fvg   A     MSESELENOMETHIONINE P - 161
1fvg_A_1581fvg   A     MSESELENOMETHIONINE T - 162
1fvg_A_1581fvg   A     MSESELENOMETHIONINE H - 166
1gve_A_2801gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE I - 282
1gve_A_2801gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 283
1gve_A_2801gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE G - 284
1gve_A_2801gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE M - 285
1gve_A_2801gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE S - 286
1gve_A_2801gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE E - 289
1gve_A_2801gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Q - 290
1gve_A_2801gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 291
1gve_A_2801gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Q - 293
1gve_A_2801gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE N - 294
1gve_A_2801gve   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 297
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gve_A_2801gve   A AC1NAP BINDING SITE FOR CHAIN AI - 282
1gve_A_2801gve   A AC1NAP BINDING SITE FOR CHAIN AL - 283
1gve_A_2801gve   A AC1NAP BINDING SITE FOR CHAIN AG - 284
1gve_A_2801gve   A AC1NAP BINDING SITE FOR CHAIN AS - 286
1gve_A_2801gve   A AC1NAP BINDING SITE FOR CHAIN AQ - 290
1gve_A_2801gve   A AC1NAP BINDING SITE FOR CHAIN AQ - 293
1gve_A_2801gve   A AC1NAP BINDING SITE FOR CHAIN AN - 294

Clusters included in this Subclass
CLUSTER: EH.3.52
CLUSTER: EH.4.32
CLUSTER: EH.5.25