ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 12.1.1

Subclass Accession number: 7673
Subclass: 12.1.1

Type: EH beta-alpha
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 8

Average sequence ID (%) : 68.8 +/- 19.9
Average RMSD (Å) : 0.763 +/- 0.450

Consensus geometry

d (Å): 13

delta (°): 45-90

theta (°): 135-180

rho (°): 315-360

Consensus Sequence:	YEPVWAIGTGKpATPp
(φψ)-conformation:	pbpaaaplagppppaa

Pattern:	[iv]	[il]	[a]	[y]	[e]	[p]	[iv]	[w]	[a]	[i]	[g]	[t]	[g]	[kr]	[stv]	[as]	[st]	[gp]	[adeq]	[dq]	[a]	[nq]	[aes]	[v]	[ch]	[aegkq]	x	[il]	[r]	[adgkrs]	[fhlvw]	[ilmv]	[akrst]
Conservation:	0.017	-0.209	0.210	1.549	0.656	1.549	0.013	3.335	0.210	0.210	1.103	0.656	1.103	0.089	-0.997	-0.380	-0.152	-0.215	-0.917	-0.279	0.210	-0.279	-0.878	0.210	-0.120	-1.272	-1.340	-0.198	0.656	-1.438	-1.372	-0.549	-1.177

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1b9b_A_164	1b9b	A	164	196	VIAYEPVWAIGTGRVATPQQAQEVHAFIRKLLS	EEEE--GGGSSSS----HHHHHHHHHHHHHHHH	bbbxbpaaaxvavxxxxaaaaaaaaaaaaaaaa
1hti_A_160	1hti	A	161	193	VLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLK	EEEE--TTTTTTS----HHHHHHHHHHHHHHHH	bbbxxxaaaxUagxbxxaaaaaaaaaaaaaaaa
1m6j_A_169	1m6j	A	170	202	ILAYEPVWAIGTGKTATPDQAQEVHQYIRKWMT	EEEE--GGGSSSS----HHHHHHHHHHHHHHHH	bxbxbxaaaxvagxbxxaaaaaaaaaaaaaaaa
1mo0_A_159	1mo0	A	160	192	VIAYEPVWAIGTGKTASGEQAQEVHEWIRAFLK	EEEE--GGGTTTS----HHHHHHHHHHHHHHHH	bxbxbpaaaxvavxxxxaaaaaaaaaaaaaaaa
1tcd_A_163	1tcd	A	164	196	VIAYEPVWAIGTGKVATPQQAQEVHELLRRWVR	EEEE--GGGTTTS----HHHHHHHHHHHHHHHH	bbbxbxaaaxUavxxxxaaaaaaaaaaaaaaaa
1tmh_A_165	1tmh	A	165	197	VIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIA	EEEE--GGGTTTS----HHHHHHHHHHHHHHHH	bbbxbpaaaxvagbxxxaaaaaaaaaaaaaaaa
1tph_1_160	1tph	1	161	193	VLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLK	EEEE--GGGTTTS----HHHHHHHHHHHHHHHH	bxbxbpaaaxvavxxxxaaaaaaaaaaaaaaaa
2btm_A_162	2btm	A	162	194	VIAYEPIWAIGTGKSSTPEDANSVCGHIRSVVS	EEEE--GGGTTTS----HHHHHHHHHHHHHHHH	bbbxbpaaaxUavbxxxaaaaaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1mo0_A_159	1mo0	A	ACTACETATE ION	E - 164
1mo0_A_159	1mo0	A	ACTACETATE ION	I - 169
1tph_1_160	1tph	1	PGHPHOSPHOGLYCOLOHYDROXAMIC ACID	E - 165
1tph_1_160	1tph	1	PGHPHOSPHOGLYCOLOHYDROXAMIC ACID	A - 169
1tph_1_160	1tph	1	PGHPHOSPHOGLYCOLOHYDROXAMIC ACID	I - 170
1tph_1_160	1tph	1	PGHPHOSPHOGLYCOLOHYDROXAMIC ACID	G - 171
1tph_1_160	1tph	1	PGHPHOSPHOGLYCOLOHYDROXAMIC ACID	T - 172
2btm_A_162	2btm	A	PGA2-PHOSPHOGLYCOLIC ACID	E - 166
2btm_A_162	2btm	A	PGA2-PHOSPHOGLYCOLIC ACID	A - 170
2btm_A_162	2btm	A	PGA2-PHOSPHOGLYCOLIC ACID	I - 171
2btm_A_162	2btm	A	PGA2-PHOSPHOGLYCOLIC ACID	G - 172
2btm_A_162	2btm	A	PGA2-PHOSPHOGLYCOLIC ACID	T - 173
2btm_A_162	2btm	A	PGA2-PHOSPHOGLYCOLIC ACID	G - 174

Clusters included in this Subclass