ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 11.3.1

Subclass Accession number: 8038
Subclass: 11.3.1

Type: HA beta-beta hairpin
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 5

Average sequence ID (%) : 47.0 +/- 25.6
Average RMSD (Å) : 0.380 +/- 0.084

Consensus geometry

d (Å): 7

delta (°): 45-90

theta (°): 135-180

rho (°): 315-360

Consensus Sequence:	pShSKchGLhcXRVG
(φψ)-conformation:	bbaaaaalaaaalbb

Pattern:	[LV]	[FHIL]	[CIV]	[AV]	x	[S]	[CFLY]	[S]	[K]	[DN]	[FLM]	[G]	[IL]	[PY]	[GNR]	[EF]	[R]	[TV]	[G]	[acn]	[CIL]	[LTY]	[asv]
Conservation:	-0.030	-1.081	-0.234	-0.280	-1.140	0.817	-0.803	0.817	1.397	0.606	-0.196	1.977	0.307	-0.186	-0.598	-0.712	1.397	-0.142	1.977	-1.349	-0.419	-0.976	-1.151

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1ajs_A_250	1ajs	A	250	272	LFCAQSFSKNFGLYNERVGNLTV	EEEEEE-TTTS--GGG-EEEEEE	bbbxbbaaaaavaaaalbbbbxb
1ars_*_250	1ars	-	250	272	LIVASSYSKNFGLYNERVGACTL	EEEEEE-TTTTT-GGG-EEEEEE	bbbxbbaaaaalaaaalbbbbbb
1iay_A_270	1iay	A	270	292	VHIVYSLSKDMGLPGFRVGIIYS	EEEEEESTTTSS-GGG-EEEEEE	bbbbbbaaaaavaaaalxbbbbx
1m7y_A_265	1m7y	A	265	287	VHVVYSLSKDLGLPGFRVGAIYS	EEEEEESSSSS--GGG-EEEEEE	bbbbbbaaaaavaaaalbbbbbb
2ay1_A_250	2ay1	A	250	272	VLIAASCSKNFGIYRERTGCLLA	EEEEEE-TTTTT-GGG-EEEEEE	bbbbxbaaaaavaaaavbbbbbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1ajs_A_250	1ajs	A	PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID	Q - 254
1ajs_A_250	1ajs	A	PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID	S - 255
1ajs_A_250	1ajs	A	PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID	F - 256
1ajs_A_250	1ajs	A	PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID	S - 257
1ajs_A_250	1ajs	A	PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID	K - 258
1ajs_A_250	1ajs	A	PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID	Y - 263
1ajs_A_250	1ajs	A	PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID	R - 266
1ajs_A_250	1ajs	A	PLA2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID	V - 267
1ars_*_250	1ars	*	PLPPYRIDOXAL-5'-PHOSPHATE	S - 254
1ars_*_250	1ars	*	PLPPYRIDOXAL-5'-PHOSPHATE	S - 255
1ars_*_250	1ars	*	PLPPYRIDOXAL-5'-PHOSPHATE	Y - 256
1ars_*_250	1ars	*	PLPPYRIDOXAL-5'-PHOSPHATE	S - 257
1ars_*_250	1ars	*	PLPPYRIDOXAL-5'-PHOSPHATE	K - 258
1ars_*_250	1ars	*	PLPPYRIDOXAL-5'-PHOSPHATE	Y - 263
1ars_*_250	1ars	*	PLPPYRIDOXAL-5'-PHOSPHATE	R - 266
1ars_*_250	1ars	*	PLPPYRIDOXAL-5'-PHOSPHATE	V - 267
1ars_*_250	1ars	*	PLPPYRIDOXAL-5'-PHOSPHATE	G - 268
1iay_A_270	1iay	A	PLPPYRIDOXAL-5'-PHOSPHATE	Y - 274
1iay_A_270	1iay	A	PLPPYRIDOXAL-5'-PHOSPHATE	S - 275
1iay_A_270	1iay	A	PLPPYRIDOXAL-5'-PHOSPHATE	L - 276
1iay_A_270	1iay	A	PLPPYRIDOXAL-5'-PHOSPHATE	S - 277
1iay_A_270	1iay	A	PLPPYRIDOXAL-5'-PHOSPHATE	K - 278
1iay_A_270	1iay	A	AVG2-AMINO-4-(2-AMINO-ETHOXY)-BUTYRIC ACID	K - 278
1iay_A_270	1iay	A	PLPPYRIDOXAL-5'-PHOSPHATE	P - 283
1iay_A_270	1iay	A	PLPPYRIDOXAL-5'-PHOSPHATE	R - 286
1iay_A_270	1iay	A	PLPPYRIDOXAL-5'-PHOSPHATE	V - 287
1iay_A_270	1iay	A	PLPPYRIDOXAL-5'-PHOSPHATE	G - 288
1m7y_A_265	1m7y	A	PPG4-(2-AMINO-ETHOXY)-2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUT-3-ENOIC ACID	V - 268
1m7y_A_265	1m7y	A	PPG4-(2-AMINO-ETHOXY)-2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUT-3-ENOIC ACID	Y - 269
1m7y_A_265	1m7y	A	PPG4-(2-AMINO-ETHOXY)-2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUT-3-ENOIC ACID	S - 270
1m7y_A_265	1m7y	A	PPG4-(2-AMINO-ETHOXY)-2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUT-3-ENOIC ACID	L - 271
1m7y_A_265	1m7y	A	PPG4-(2-AMINO-ETHOXY)-2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUT-3-ENOIC ACID	S - 272
1m7y_A_265	1m7y	A	PPG4-(2-AMINO-ETHOXY)-2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUT-3-ENOIC ACID	K - 273
1m7y_A_265	1m7y	A	MPD2-METHYL-2,4-PENTANEDIOL	K - 273
1m7y_A_265	1m7y	A	PPG4-(2-AMINO-ETHOXY)-2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUT-3-ENOIC ACID	P - 278
1m7y_A_265	1m7y	A	MPD2-METHYL-2,4-PENTANEDIOL	P - 278
1m7y_A_265	1m7y	A	PPG4-(2-AMINO-ETHOXY)-2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUT-3-ENOIC ACID	R - 281
1m7y_A_265	1m7y	A	MPD2-METHYL-2,4-PENTANEDIOL	R - 281
1m7y_A_265	1m7y	A	PPG4-(2-AMINO-ETHOXY)-2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUT-3-ENOIC ACID	V - 282
1m7y_A_265	1m7y	A	PPG4-(2-AMINO-ETHOXY)-2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-BUT-3-ENOIC ACID	G - 283
2ay1_A_250	2ay1	A	PLPPYRIDOXAL-5'-PHOSPHATE	A - 254
2ay1_A_250	2ay1	A	PLPPYRIDOXAL-5'-PHOSPHATE	C - 256
2ay1_A_250	2ay1	A	PLPPYRIDOXAL-5'-PHOSPHATE	T - 267

Clusters included in this Subclass

CLUSTER: HA.10.6