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Information on SUBCLASS 1.1.2
Subclass Accession number: 8130
Subclass: 1.1.2 PSSM
Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 92

Average sequence ID (%) : 15.2 +/- 16.4
Average RMSD (Å) : 0.497 +/- 0.174

Consensus geometry
d (Å): 9 delta (°): 45-90 theta (°): 90-135 rho (°): 90-135
Consensus Sequence: XXGhX
(φψ)-conformation: aagbb
Pattern: x[acfgilmpvwy]x[adegknqrst]x[degkn]x[dehknpqrst][filtvwy]x
Conservation:-0.685-0.159-0.3560.174-0.5702.742-0.353-0.3150.049-0.526
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a4m_A_2461a4m   A251260RLLKENMHFEHHHHTT-EEEaaaaalxxbx
1a4s_A_3421a4s   A354363QAKKEGARVLHHHHHT-EEEaaaaagxbxa
1aqu_A_1161aqu   A117126SFWEKNCKMIHHHHTT-EEEaaaaalxxbb
1b0z_A_1801b0z   A184193LADQEGYETFHHHHHT-EEEaaaaavxxbb
1bbu_A_1771bbu   A196204FMVNRGFME.HHHTTT-EE.aaaaavxbx.
1bxs_A_3471bxs   A359367SGKKEGAKL.HHHHTT-EE.aaaaavxxx.
1c0a_A_1321c0a   A151159FMDDHGFLD.HHHHTT-EE.aaaaavxxx.
1c0p_A_11391c0p   A11491158ELQKLGATFEHHHHTT-EEEaaaaavxbbb
1c30_A_1071c30   A107115VLEEFGVTM.HHHHTT-EE.aaaaavxxx.
1cdo_A_3051cdo   A306315IQLIAGRTWKHHHHTT-EEEaaaaagxbbb
1cf2_O_381cf2   O4251MALKKGYDLYHHHHTT--EEaaaaavxxxb
1chu_A_2601chu   A261270ALRGEGAYLKHHHHTT-EEEaaaaagxbbb
1cqz_A_1031cqz   A111120ALKKKGFTTCHHHHTS-EEEaaaaavbxbb
1d1t_A_3061d1t   A306315MLLFTGRTWKHHHHTT-EEEaaaaagxbbb
1d3v_A_1841d3v   A189198IIKTLGIKYFHHHHHT-EEEaaaaavxxbb
1d9e_D_41221d9e   D41274136AMAKTGAVINHHHHH--EEEaaaaavxxbb
1ddg_A_5361ddg   A541550RWINDGAHIYHHHHTT-EEEaaaaavxxbb
1dmr_*_2031dmr   -209218ALKAKGTKVIHHHHHT-EEEaaaaavpxbb
1dpj_A_2251dpj   A231239INAEIGAKK.HHHHHT-EE.aaaaavbbx.
1e1o_A_1771e1o   A196204FMVARGFME.HHHTTT-EE.aaaaavxbx.
1e39_A_2531e39   A264273NAVKRNIDLRHHHHTT-EEEaaaaalxxbb
1e39_A_3791e39   A379388AVRGNGAILVHHHHTT-EEEaaaaagxbbb
1e3i_A_3071e3i   A308317VDVILGRSINHHHHTT-EEEaaaaagxbbb
1e5x_A_2251e5x   A226235QPIANGAFVLHHHHTT-EEEaaaaavxxxx
1ebd_A_851ebd   A106115LLKGNKVEIVHHHTTT-EEEaaaaalbxxb
1eok_A_651eok   A7483SLQSRGIKVLHHHTTT-EEEaaaaavxxbb
1eov_A_2421eov   A261269YLATKKFTE.HHHHTT-EE.aaaaavxbx.
1eu1_A_2021eu1   A209217ALKEKGTRV.HHHHHT-EE.aaaaavpxb.
1ew2_A_1321ew2   A135144RAKKAGKSVGHHHHTT-EEEaaaaavxxbb
1f0n_A_1971f0n   A199208KLVANNTRLWHHHHTT-EEEaaaaalxxbb
1fmt_A_131fmt   A2130ALLSSGHNVVHHHHTT-EEEaaaaalxxxa
1fy2_A_1031fy2   A108117DRVKRGALYIHHHHTT-EEEaaaaagxxbb
1g3m_A_1151g3m   A116125SFWEKDCKIIHHHHTT-EEEaaaaalxxbb
1g63_A_1241g63   A132140LLKNNDVKV.HHHTTT-EE.aaaaavxxb.
1g6s_A_481g6s   A5665ALTALGVSYTHHHHTT-EEEaaaaavxxbb
1g8k_A_4921g8k   A501510EATQNGGLFVHHHTTT--EEaaaaavxbxb
1gpm_A_871gpm   A92101MAMQLGGHVEHHHHHT-EEEaaaaagxbbb
1gpw_B_671gpw   B7281KHVEDERYVVHHHHTT-EEEaaaaavbpbb
1gq6_A_1941gq6   A195204YARGHGVRVVHHHHTT-EEEaaaaavxxxb
1gte_A_2381gte   A247256LMKDLGVKIIHHHTTT-EEEaaaaavxbbb
1gte_A_3741gte   A379388LAKEEKCEFLHHHHTT-EEEaaaaavxxbb
1ht0_A_3061ht0   A306315MLLLTGRTWKHHHHTT-EEEaaaaagxbbb
1hv9_A_2011hv9   A204213LAYQEGREIVHHHTTT--EEaaaaavxbbb
1i50_B_5521i50   B557565FLSEWGMEP.HHHHTT-EE.aaaaavxxx.
1ig0_A_1031ig0   A108117YYRKNKVTIIHHHHTT-EEEaaaaavxxbb
1ii2_A_3921ii2   A402411KMQKHNSRVWHHHHHT-EEEaaaaalxxbb
1j0a_A_1101j0a   A114123LDKIMGIETRHHHHTT-EEEaaaaavxxbb
1j4a_A_861j4a   A8897KAKELGFQITHHHHTT-EEEaaaaavxbbb
1j5s_A_1361j5s   A139148LLRDMKVEILHHHHTTEEEEaaaaalxabb
1j7n_A_681j7n   A7382MYKAIGGKIYHHHHTT-EEEaaaaavxbbb
1ja1_A_1831ja1   A191199RLEQLGAQR.HHHHTT-EE.aaaaagxbx.
1jkx_A_411jkx   A4554RARQAGIATHHHHHTT-EEEaaaaavbpbb
1jv1_A_4181jv1   A432440WVLNAGGHF.HHHHTT-EE.aaaaavxbb.
1jvn_A_661jvn   A7180EYIESGKPIMHHHHTT--EEaaaaavxwbb
1k0i_A_1021k0i   A112121AREACGATTVHHHHTT-EEEaaaaavxxbb
1k6w_A_2551k6w   A264273LLKMSGINFVHHHHHT-EEEaaaaavxbbb
1k8t_A_3361k8t   A337345NLIKSGVAT.HHHHTT-EE.aaaaavpxx.
1kcz_A_201kcz   A2130RAIKKGAGHDHHHHTT-EEEaaaaagpxxb
1kf6_A_2461kf6   A246255GCRGEGGILVHHHHTT-EEEaaaaavxbbb
1l0w_A_1381l0w   A157165FLDREGFVQ.HHHHTT-EE.aaaaavxbx.
1l1l_A_5831l1l   A586595ALKACGYRTEHHHHTT-EEEaaaaagxxbb
1lok_A_1561lok   A164173QYKSEGKNVVHHHHTT-EEEaaaaavxxxa
1lpf_A_871lpf   A108117LFKANGVTSFHHHHHTEEEEaaaaavbxxb
1ls6_A_1161ls6   A117126TLLDQKVKVVHHHHTT-EEEaaaaalxxbb
1ltm_*_2921ltm   -294302QLAAAGLTP.HHHHTT-EE.aaaaagbbx.
1m6h_A_3051m6h   A305314FQLVTGRTWKHHHHTT-EEEaaaaagxbbb
1n8f_A_1191n8f   A132141DINDSGLPAAHHHHTT--EEaaaaagbxbb
1n8k_A_3061n8k   A306315MLLLSGRTWKHHHHTT-EEEaaaaagxbbb
1ndw_A_2461ndw   A251260RLRQENMHFEHHHHTT-EEEaaaaavpxbx
1nek_A_1411nek   A152161QNLKNHTTIFHHHHTT-EEEaaaaalxxbb
1nek_A_2561nek   A256265GCRGEGGYLLHHHHHT-EEEaaaaagxxbb
1nj1_A_2421nj1   A243252FARTFEIKFEHHHHHT-EEEaaaaavxbbx
1nsq_A_221nsq   A2837RFEQKGFKLVHHHHHT-EEEaaaaagxxxa
1ny1_A_2281ny1   A238247DLKKQGYTFKHHHHHT-EEEaaaaagxbbb
1o04_A_3471o04   A359368TGKQEGAKLLHHHHTT-EEEaaaaavxxxa
1o94_A_5741o94   A580589RLHELHVEELHHHHTT-EEEaaaaavxxbb
1o9j_A_3471o9j   A359368SGKKEGAKLEHHHHHT-EEEaaaaagxbxa
1oi7_A_181oi7   A2635QMLTYGTKIVHHHHHT-EEEaaaaagxxxa
1p0f_A_13051p0f   A13051314LLLLTGRSLKHHHHTT-EEEaaaaagxbbb
1p49_A_1181p49   A121130LLKDQGYSTAHHHHTT-EEEaaaaavxxbb
1pix_A_1681pix   A175184ELNQLGIPVIHHHHTT--EEaaaaavbxbb
1pq3_A_2031pq3   A208217ILKNYDIQYFHHHHTT-EEEaaaaalxxbb
1ps9_A_5761ps9   A582591TLLSRGVKMIHHHHTT-EEEaaaaavxbbb
1psd_A_911psd   A93102AAAKRGIPVFHHHTTT--EEaaaaavbxbb
1qla_A_1561qla   A167176ECLKLGVSIQHHHHHT-EEEaaaaavxxxb
1qo8_A_3741qo8   A374383TVRGVGAVMVHHHHTT-EEEaaaaaNxbbb
1qrp_E_2251qrp   E231239IQSDIGASE.HHHHTT-EE.aaaaavxbx.
1trb_*_611trb   -7180HATKFETEIIHHHHTT-EEEaaaaavxxxb
2ayq_A_3112ayq   A323330DVLQDGYC..HHHHTTEE..aaaaavbb..
2cev_A_1792cev   A184193FIREKGIKIYHHHHHT-EEEaaaaavxxbb
2nac_A_1292nac   A131140SAIDRNVTVAHHHHTT-EEEaaaaalxxbb
4uag_A_794uag   A8392AAADAGIEIVHHHHTT-EEEaaaaavxxbb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1bxs_A_3471bxs   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE E - 348
1bxs_A_3471bxs   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE Q - 349
1bxs_A_3471bxs   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE K - 352
1cdo_A_3051cdo   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 309
1cf2_O_381cf2   O     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE E - 39
1d1t_A_3061d1t   A     ACTACETATE ION F - 309
1d1t_A_3061d1t   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE F - 309
1d3v_A_1841d3v   A     ABH2(S)-AMINO-6-BORONOHEXANOIC ACID E - 186
1dmr_*_2031dmr   *     PGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE I - 220
1e1o_A_1771e1o   A     GOLGLYCEROL L - 190
1e1o_A_1771e1o   A     GOLGLYCEROL R - 194
1e1o_A_1771e1o   A     GOLGLYCEROL E - 204
1e39_A_2531e39   A     FADFLAVIN-ADENINE DINUCLEOTIDE V - 253
1e39_A_3791e39   A     FUMFUMARIC ACID A - 379
1e39_A_3791e39   A     FUMFUMARIC ACID R - 381
1e3i_A_3071e3i   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 311
1e3i_A_3071e3i   A     CXFCYCLOHEXYLFORMAMIDE I - 311
1e5x_A_2251e5x   A     MSESELENOMETHIONINE V - 225
1e5x_A_2251e5x   A     MSESELENOMETHIONINE Q - 226
1e5x_A_2251e5x   A     MSESELENOMETHIONINE I - 228
1e5x_A_2251e5x   A     MSESELENOMETHIONINE A - 229
1e5x_A_2251e5x   A     MSESELENOMETHIONINE N - 230
1eu1_A_2021eu1   A     CSD3-SULFINOALANINE V - 217
1ew2_A_1321ew2   A     MGMAGNESIUM ION T - 147
1ew2_A_1321ew2   A     MGMAGNESIUM ION T - 149
1f0n_A_1971f0n   A     MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID N - 204
1f0n_A_1971f0n   A     MES2-(N-MORPHOLINO)-ETHANESULFONIC ACID R - 206
1g6s_A_481g6s   A     GPJGLYPHOSATE D - 49
1g6s_A_481g6s   A     FMTFORMIC ACID L - 54
1g6s_A_481g6s   A     FMTFORMIC ACID L - 57
1g6s_A_481g6s   A     FMTFORMIC ACID T - 58
1g6s_A_481g6s   A     FMTFORMIC ACID V - 62
1g6s_A_481g6s   A     FMTFORMIC ACID S - 63
1g6s_A_481g6s   A     FMTFORMIC ACID Y - 64
1g6s_A_481g6s   A     FMTFORMIC ACID T - 65
1g6s_A_481g6s   A     FMTFORMIC ACID L - 66
1g8k_A_4921g8k   A     MGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE I - 513
1g8k_A_4921g8k   A     MGD2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE N - 514
1gpm_A_871gpm   A     CITCITRIC ACID Y - 87
1gpm_A_871gpm   A     CITCITRIC ACID G - 88
1gpm_A_871gpm   A     CITCITRIC ACID Q - 90
1gte_A_3741gte   A     FADFLAVIN-ADENINE DINUCLEOTIDE E - 376
1ht0_A_3061ht0   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 309
1ja1_A_1831ja1   A     FMNFLAVIN MONONUCLEOTIDE A - 183
1jkx_A_411jkx   A     138N-[5'-O-PHOSPHONO-RIBOFURANOSYL]-2-[2-HYDROXY-2-[4-[GLUTAMIC ACID]-N-CARBONYLPHENYL]-3-[2-AMINO-4-HYDROXY -QUINAZOLIN-6-YL]-PROPANYLAMINO]-ACETAMIDE R - 45
1jvn_A_661jvn   A     143S-2,3-DIHYDRO-5-GLYCIN-2-YL-ISOXAZOL-3-YL-CYSTEINE G - 81
1k0i_A_1021k0i   A     FADFLAVIN-ADENINE DINUCLEOTIDE Q - 102
1kf6_A_2461kf6   A     OAAOXALOACETATE ION G - 246
1lok_A_1561lok   A     SCNTHIOCYANATE ION K - 170
1lok_A_1561lok   A     SCNTHIOCYANATE ION N - 171
1lok_A_1561lok   A     SCNTHIOCYANATE ION V - 172
1lok_A_1561lok   A     SCNTHIOCYANATE ION V - 173
1lok_A_1561lok   A     SCNTHIOCYANATE ION S - 174
1lpf_A_871lpf   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 119
1lpf_A_871lpf   A     FADFLAVIN-ADENINE DINUCLEOTIDE H - 120
1lpf_A_871lpf   A     FADFLAVIN-ADENINE DINUCLEOTIDE G - 121
1lpf_A_871lpf   A     FADFLAVIN-ADENINE DINUCLEOTIDE K - 122
1m6h_A_3051m6h   A     PO4PHOSPHATE ION T - 312
1m6h_A_3051m6h   A     PO4PHOSPHATE ION K - 314
1n8f_A_1191n8f   A     PEPPHOSPHOENOLPYRUVATE E - 143
1n8k_A_3061n8k   A     NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM) L - 309
1nek_A_1411nek   A     FADFLAVIN-ADENINE DINUCLEOTIDE T - 141
1nek_A_1411nek   A     FADFLAVIN-ADENINE DINUCLEOTIDE L - 146
1nek_A_2561nek   A     OAAOXALOACETATE ION G - 256
1nek_A_2561nek   A     OAAOXALOACETATE ION R - 258
1ny1_A_2281ny1   A     MSESELENOMETHIONINE N - 228
1ny1_A_2281ny1   A     MSESELENOMETHIONINE A - 231
1ny1_A_2281ny1   A     MSESELENOMETHIONINE L - 232
1ny1_A_2281ny1   A     MSESELENOMETHIONINE D - 233
1ny1_A_2281ny1   A     MSESELENOMETHIONINE A - 235
1ny1_A_2281ny1   A     MSESELENOMETHIONINE L - 239
1p0f_A_13051p0f   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 1308
1p49_A_1181p49   A     ALS2-AMINO-3-OXO-4-SULFO-BUTYRIC ACID K - 134
1p49_A_1181p49   A     CACALCIUM ION K - 134
1pq3_A_2031pq3   A     S2CS-2-(BORONOETHYL)-L-CYSTEINE E - 205
1ps9_A_5761ps9   A     MDE5-MERCAPTOETHANOL-2-DECENOYL-COENZYME A W - 577
1ps9_A_5761ps9   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE H - 579
1ps9_A_5761ps9   A     MDE5-MERCAPTOETHANOL-2-DECENOYL-COENZYME A R - 580
1qla_A_1561qla   A     FADFLAVIN-ADENINE DINUCLEOTIDE L - 161

Clusters included in this Subclass
CLUSTER: HE.1.19
CLUSTER: HE.2.19
CLUSTER: HE.2.9
CLUSTER: HE.3.9
CLUSTER: HE.4.12
CLUSTER: HE.4.33