Information on SUBCLASS 1.2.2 |
Subclass Accession number: 8138
Subclass: 1.2.2 Type: HE alpha-beta DB: ArchDB-EC Image coordinates: Consensus coordinates: |
Number of loops: 109 Average sequence ID (%) : 13.2 +/- 15.5 Average RMSD (Å) : 0.466 +/- 0.163 Consensus geometry
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Consensus Sequence: | pXchX |
(φψ)-conformation: | aalbb |
Pattern: | x | [acfgilmpvwy] | x | [adegknqrst] | x | [degknqrs] | [acfgilmvy] | x | x |
Conservation: | -0.975 | -0.122 | -0.513 | 0.679 | -0.738 | 1.968 | 0.502 | -0.800 | -1.000 |
Loops included in this Subclass |
Loop | PDB | Chain | Start | End | Sequence | Sec Struct | Ramachandran |
1a9x_B_1703 | 1a9x | B | 1708 | 1716 | MLVDRGCRL | HHHHTTEEE | aaaaagxbb |
1air_*_287 | 1air | - | 288 | 295 | DFSTYSIT. | HHHHHTEE. | aaaaalbb. |
1akz_*_193 | 1akz | - | 194 | 202 | GWAKQGVLL | HHHHTTEEE | aaaaagxxb |
1apm_E_140 | 1apm | E | 156 | 163 | YLHSLDLI. | HHHHTTEE. | aaaaavxb. |
1b7b_A_172 | 1b7b | A | 177 | 185 | TLIKNDIIT | HHHHTTEEE | aaaaalbxx |
1bj4_A_370 | 1bj4 | A | 376 | 383 | VLEACSIA. | HHHHTTEE. | aaaaavbx. |
1bjn_A_310 | 1bjn | A | 316 | 323 | ESFAAGLH. | HHHHTTEE. | aaaaavbx. |
1bpy_A_276 | 1bpy | A | 285 | 293 | HALEKGFTI | HHHHTTEEE | aaaaavbbb |
1bs0_A_328 | 1bs0 | A | 337 | 344 | KLRQQGCW. | HHHHTTEE. | aaaaavbx. |
1bt4_A_307 | 1bt4 | A | 316 | 323 | ASEQEGFV. | HHHHTTEE. | aaaaavxb. |
1c7g_A_124 | 1c7g | A | 129 | 137 | HQEKNGATF | HHHHTTEEE | aaaaavbbx |
1c96_A_405 | 1c96 | A | 408 | 416 | VLRDVGGIV | HHHHTTEEE | aaaaagxbx |
1c96_A_646 | 1c96 | A | 650 | 658 | EPRHLGGRA | HHHHTTEEE | aaaaagxab |
1cjw_A_165 | 1cjw | A | 167 | 175 | FYQRFGFHP | HHHTTTEEE | aaaaavxbw |
1cki_A_105 | 1cki | A | 121 | 128 | YIHSKNFI. | HHHHTTEE. | aaaaavbb. |
1cm8_A_127 | 1cm8 | A | 143 | 150 | YIHAAGII. | HHHHTTEE. | aaaaavxb. |
1cqz_A_191 | 1cqz | A | 192 | 200 | PARDMGMVT | HHHHTT-EE | aaaaagbxx |
1cr0_A_439 | 1cr0 | A | 452 | 460 | FAKSTGVVL | HHHH--EEE | aaaaavxbb |
1cxv_A_195 | 1cxv | A | 203 | 210 | LGHSLGLD. | HHHHHTEE. | aaaaagxx. |
1d7u_A_378 | 1d7u | A | 385 | 392 | ECMNLGLS. | HHHHTTEE. | aaaaavbx. |
1db3_A_258 | 1db3 | A | 265 | 273 | AAAQLGIKL | HHHTTTEEE | aaaaavbxb |
1dfo_A_330 | 1dfo | A | 336 | 343 | ALGRANIT. | HHHHTTEE. | aaaaavbx. |
1djx_A_262 | 1djx | A | 263 | 270 | TAKAQRQM. | HHHHTTEE. | aaaaalbb. |
1dun_*_57 | 1dun | - | 58 | 66 | SMAKQGLLI | HHHHTTEEE | aaaaagxbx |
1em8_A_121 | 1em8 | A | 133 | 141 | AYRVAGFNL | HHHHTTEEE | aaaaavxxb |
1f0l_A_310 | 1f0l | A | 310 | 317 | IGSVMGIA. | HHHHHTEE. | aaaaavbb. |
1f89_A_175 | 1f89 | A | 180 | 188 | LSARKGAFA | HHHHTTEEE | aaaaagpab |
1fbl_*_212 | 1fbl | - | 220 | 227 | LGHSLGLS. | HHHHTTEE. | aaaaagxb. |
1fc4_A_193 | 1fc4 | A | 199 | 206 | LADKYDAL. | HHHHTTEE. | aaaaalbx. |
1fc4_A_335 | 1fc4 | A | 344 | 351 | ELQKEGIY. | HHHHTTEE. | aaaaavbx. |
1fg7_A_307 | 1fg7 | A | 313 | 320 | SLWDQGII. | HHHHTTEE. | aaaaavbx. |
1fmt_A_13 | 1fmt | A | 21 | 29 | ALLSSGHNV | HHHHTT-EE | aaaaalxxx |
1fot_A_184 | 1fot | A | 200 | 207 | YLHSKDII. | HHHTTTEE. | aaaaalbb. |
1fvr_A_938 | 1fvr | A | 954 | 961 | YLSQKQFI. | HHHHTTEE. | aaaaavxb. |
1fy2_A_103 | 1fy2 | A | 108 | 116 | DRVKRGALY | HHHHTT-EE | aaaaagxxb |
1g63_A_124 | 1g63 | A | 132 | 140 | LLKNNDVKV | HHHTTT-EE | aaaaavxxb |
1g8m_A_547 | 1g8m | A | 551 | 559 | RAKRIGVQF | HHHTTTEEE | aaaaavxab |
1gjo_A_600 | 1gjo | A | 616 | 623 | YLASQKCI. | HHHHTTEE. | aaaaavbb. |
1gkm_A_116 | 1gkm | A | 124 | 132 | ALVNAEVYP | HHHHHTEEE | aaaaavbbp |
1gkr_A_75 | 1gkr | A | 81 | 89 | SAAVGGITT | HHHHHTEEE | aaaaavxab |
1h1w_A_179 | 1h1w | A | 195 | 202 | YLHGKGII. | HHHHTTEE. | aaaaavbb. |
1h26_C_101 | 1h26 | C | 117 | 124 | FCHSHRVL. | HHHHTTEE. | aaaaalbx. |
1h4l_A_100 | 1h4l | A | 116 | 123 | FCHSRNVL. | HHHHTTEE. | aaaaavbb. |
1h5q_A_22 | 1h5q | A | 30 | 38 | AVAAAGANV | HHHHTTEEE | aaaaagbxb |
1h6v_A_230 | 1h6v | A | 239 | 247 | HMEEHGIKF | HHHHTTEEE | aaaaavbxb |
1h8e_A_240 | 1h8e | A | 256 | 264 | YFRDNGKHA | HHHTTT-EE | aaaaavbbb |
1hv9_A_229 | 1hv9 | A | 246 | 254 | KLLLAGVML | HHHHTT-EE | aaaaagxxb |
1ia8_A_104 | 1ia8 | A | 120 | 127 | YLHGIGIT. | HHHHTTEE. | aaaaavbb. |
1igw_B_330 | 1igw | B | 339 | 347 | QLSDMGYKF | HHHHHTEEE | aaaaagxab |
1ih7_A_361 | 1ih7 | A | 372 | 379 | SLKEQNKV. | HHHTTTEE. | aaaaalxb. |
1ir3_A_1106 | 1ir3 | A | 1122 | 1129 | YLNAKKFV. | HHHHTTEE. | aaaaavbb. |
1itu_A_134 | 1itu | A | 139 | 147 | ALYQLGMRY | HHHHTTEEE | aaaaagxab |
1iw7_C_959 | 1iw7 | C | 965 | 972 | ELFLQGKV. | HHHHTTEE. | aaaaavbb. |
1j1u_A_43 | 1j1u | A | 54 | 62 | DLQNAGFDI | HHHHTTEEE | aaaaavxxb |
1j8u_A_251 | 1j8u | A | 256 | 264 | GGLAFRVFH | HHHHTTEEE | aaaaalbbx |
1je0_A_167 | 1je0 | A | 170 | 178 | KWSSRGNIA | HHHTTTEEE | aaaaavbab |
1jf9_A_344 | 1jf9 | A | 350 | 357 | FLDNYGIA. | HHHHTTEE. | aaaaavbx. |
1jks_A_113 | 1jks | A | 129 | 136 | YLHSLQIA. | HHHHTTEE. | aaaaalbx. |
1jqk_A_460 | 1jqk | A | 468 | 476 | SLAKRNVLV | HHHHTTEEE | aaaaavbxb |
1k2w_A_16 | 1k2w | A | 24 | 32 | AYVREGARV | HHHHTTEEE | aaaaavbxb |
1k2y_X_61 | 1k2y | X | 71 | 79 | GLVDCGCQV | HHHTBT-EE | aaaaagxxx |
1k4g_A_283 | 1k4g | A | 286 | 293 | RSGRNGQA. | HHHHHTEE. | aaaaagxb. |
1krh_A_72 | 1krh | A | 73 | 81 | EEAQQGYVL | HHHHHTEEE | aaaaagxbb |
1kut_A_146 | 1kut | A | 158 | 166 | FFERANFEL | HHHTTTEEE | aaaaavbbx |
1l6r_A_121 | 1l6r | A | 127 | 135 | EAESRGFVI | HHHTTTEEE | aaaaavbbb |
1lc5_A_311 | 1lc5 | A | 314 | 321 | RLLTQRIL. | HHHTTTEE. | aaaaavbb. |
1lk9_A_376 | 1lk9 | A | 379 | 386 | TFQNGRIN. | HHHHTTEE. | aaaaavbx. |
1lt8_A_278 | 1lt8 | A | 287 | 295 | EAYNLGVRY | HHHHHTEEE | aaaaagxab |
1ltz_A_104 | 1ltz | A | 109 | 117 | EHLANRRFP | HHHHTTEEE | aaaaavbbw |
1lvl_*_212 | 1lvl | - | 221 | 229 | SLKKLGIAL | HHHHHT-EE | aaaaavbxb |
1m14_A_787 | 1m14 | A | 803 | 810 | YLEDRRLV. | HHHHTTEE. | aaaaalbb. |
1m15_A_294 | 1m15 | A | 300 | 308 | IASKFNLQV | HHHHTTEEE | aaaaalbbb |
1m2r_A_130 | 1m2r | A | 146 | 153 | YCHSQGIM. | HHHHTTEE. | aaaaavbb. |
1mkp_*_225 | 1mkp | - | 227 | 235 | VLEEFGIKY | HHHHTTEEE | aaaaavxab |
1mq4_A_230 | 1mq4 | A | 246 | 253 | YCHSKRVI. | HHHHTTEE. | aaaaalxb. |
1mq7_A_67 | 1mq7 | A | 67 | 75 | LATRVGLSI | HHHHTTEEE | aaaaavxbb |
1n16_A_308 | 1n16 | A | 311 | 319 | VLKRTRLQK | HHHHHTEEE | aaaaavbbb |
1na7_A_130 | 1na7 | A | 146 | 153 | YCHSMGIM. | HHHHTTEE. | aaaaavbb. |
1nhp_*_191 | 1nhp | - | 200 | 208 | EMEANNITI | HHHTTTEEE | aaaaalbxb |
1nox_*_125 | 1nox | - | 146 | 154 | LLEAYGLGS | HHHHTT-EE | aaaaavbxb |
1nui_A_88 | 1nui | A | 90 | 98 | TCQKAGYWI | HHHHHTEEE | aaaaavbbb |
1nw9_B_183 | 1nw9 | B | 193 | 201 | RFSSLHFMV | HHHHTTEEE | aaaaavxxx |
1nxk_A_169 | 1nxk | A | 176 | 183 | YLHSINIA. | HHHHTTEE. | aaaaavbb. |
1nyr_A_268 | 1nyr | A | 284 | 292 | KEVSMGYDH | HHHHTTEEE | aaaaavxbx |
1o63_A_153 | 1o63 | A | 154 | 162 | TLKENNLEI | HHHHTTEEE | aaaaavxbx |
1o6y_A_112 | 1o6y | A | 128 | 135 | FSHQNGII. | HHHHTTEE. | aaaaavbb. |
1oao_A_479 | 1oao | A | 487 | 495 | ELLKNNVFV | HHHHTTEEE | aaaaavxxb |
1ohv_A_419 | 1ohv | A | 428 | 435 | IARNKGVM. | HHHHTTEE. | aaaaagbx. |
1omw_A_291 | 1omw | A | 307 | 314 | HMHNRFVV. | HHHHTTEE. | aaaaavbx. |
1onw_A_89 | 1onw | A | 91 | 99 | RLTEAGVTS | HHHHTTEEE | aaaaavxab |
1pb1_A_370 | 1pb1 | A | 382 | 389 | GAINAKTV. | HHHHTTEE. | aaaaavbb. |
1phk_*_123 | 1phk | - | 139 | 146 | ALHKLNIV. | HHHHTTEE. | aaaaalbb. |
1pkg_A_766 | 1pkg | A | 782 | 789 | FLASKNCI. | HHHHTTEE. | aaaaavbb. |
1pme_*_123 | 1pme | - | 139 | 146 | YIHSANVL. | HHHHTTEE. | aaaaavbb. |
1prx_A_49 | 1prx | A | 60 | 68 | EFAKRNVKL | HHHTTTEEE | aaaaavbxb |
1pyo_A_57 | 1pyo | A | 67 | 75 | LFKLLGYDV | HHHHTTEEE | aaaaavxxx |
1qh4_A_308 | 1qh4 | A | 311 | 319 | VLKRLRLQK | HHHHHTEEE | aaaaalbbb |
1qj5_A_376 | 1qj5 | A | 382 | 389 | FFVEQGVW. | HHHHTTEE. | aaaaavbb. |
1qpc_A_338 | 1qpc | A | 354 | 361 | FIEERNYI. | HHHHTTEE. | aaaaavbb. |
1rlv_A_216 | 1rlv | A | 225 | 233 | NLKERGFVV | HHHTTT-EE | aaaaavxxb |
1sft_A_93 | 1sft | A | 95 | 103 | LAAQQRIAL | HHHHTTEEE | aaaaalxxb |
1tyf_A_19 | 1tyf | A | 22 | 30 | RLLKERVIF | HHHHTTEEE | aaaaavbbb |
1udg_*_136 | 1udg | - | 137 | 145 | KWARDGVLL | HHHHTTEEE | aaaaavxxx |
1xo1_A_44 | 1xo1 | A | 54 | 62 | LAKSYSART | HHHHTTEEE | aaaaalxab |
2oat_A_390 | 2oat | A | 396 | 403 | RLRDNGLL. | HHHHTTEE. | aaaaavbb. |
2ovw_A_77 | 2ovw | A | 79 | 87 | AYKNAGITT | HHHHTTEEE | aaaaavbbb |
2scu_B_240 | 2scu | B | 244 | 252 | QAAQWELNY | HHHHTTEEE | aaaaalbbx |
2sfa_*_179 | 2sfa | - | 182 | 190 | ALSAYGVSI | HHHHHTEEE | aaaaavbbx |
4gsa_A_383 | 4gsa | A | 392 | 399 | GMLEQGIY. | HHHHTTEE. | aaaaavbb. |
PDB ligands within a cut-off distance of 6 Å in this subclass |
PDB Site Annotated loops in this subclass |
Loop | PDB | Chain | Site | Residue |
1h1w_A_179 | 1h1w | A | AC4GOL BINDING SITE FOR CHAIN A | E - 194 |
1h1w_A_179 | 1h1w | A | BC5SO4 BINDING SITE FOR CHAIN A | K - 199 |
1h5q_A_22 | 1h5q | A | AC1NAP BINDING SITE FOR CHAIN A | Y - 42 |
Clusters included in this Subclass |
CLUSTER: HE.0.4 |
CLUSTER: HE.1.1 |
CLUSTER: HE.1.25 |
CLUSTER: HE.2.2 |
CLUSTER: HE.2.76 |
CLUSTER: HE.3.6 |