Logo
Information on SUBCLASS 1.2.12
Subclass Accession number: 8148
Subclass: 1.2.12 PSSM
Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 7

Average sequence ID (%) : 15.6 +/- 20.9
Average RMSD (Å) : 0.443 +/- 0.181

Consensus geometry
d (Å): 7 delta (°): 45-90 theta (°): 135-180 rho (°): 270-315
Consensus Sequence: pXcXX
(φψ)-conformation: aalbb
Pattern: [afily][AEQR][aekqt]x[iklv][DNQR]x[FHILV][ailv][ADQR]x[gn]xx[npv]
Conservation:-0.3940.745-0.210-0.987-0.1081.200-0.9250.2280.1860.530-0.0912.462-1.283-1.3720.020
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1exp_*_2151exp   -215229FRQNLQRFADLGVDVHHHHHHHHHTTT-EEaaaaaaaaaaavbxb
1frb_*_2441frb   -245259AQVLIRFHIQRNVVVHHHHHHHHHTTT-EEaaaaaaaaaaalbxb
1hiz_A_2451hiz   A248262IEKTINMFAALGLDNHHHHHHHHHTTT-EEaaaaaaaaaaavxxb
1od8_A_2181od8   A218232FRTTLQNFAALGVDVHHHHHHHHHTTT-EEaaaaaaaaaaavbxb
1pjr_*_1691pjr   -177190YQEYQQRLLRNHSL.HHHHHHHHHHTTEE.aaaaaaaaaaalbb.
1scj_B_3231scj   B323337SAKKKDVISQKGGKVHHHHHHHHHTTT-EEaaaaaaaaaaagpbx
2cev_A_682cev   A7892LAAAVDQVVQRGRFPHHHHHHHHHHTT-EEaaaaaaaaaaavbxw
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1exp_*_2151exp   *     GLCGLUCOSE E - 233
1exp_*_2151exp   *     G2F2-DEOXY-2FLUORO-GLUCOSE E - 233
1frb_*_2441frb   *     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE A - 245
1frb_*_2441frb   *     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Q - 246
1hiz_A_2451hiz   A     GLCGLUCOSE E - 266
1od8_A_2181od8   A     IMDIMIDAZOLE D - 231
1od8_A_2181od8   A     XDLXYLOSE-DERIVED ISOFAGOMINE LACTAM E - 236
1od8_A_2181od8   A     XYPBETA-D-XYLOPYRANOSE E - 236
1od8_A_2181od8   A     IMDIMIDAZOLE E - 236
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1exp_*_2151exp   * NUCCATALYTIC NUCLEOPHILE, COVALENTLY LINKED TO THE FLUOROCELLOBIOSIDE.E - 233
1hiz_A_2451hiz   A GL1GLC BINDING SITE FOR RESIDUE A1381E - 266
1od8_A_2181od8   A AC9XDL BINDING SITE FOR CHAIN AE - 236

Clusters included in this Subclass
CLUSTER: HE.3.74