ArchDB - Biological DataBase of Protein Loops

Grup de Recerca en Informàtica Biomèdica

Information on SUBCLASS 2.2.8

Subclass Accession number: 8207
Subclass: 2.2.8

PSSM

Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates:

Rasmol PDB

Jmol PDB

Consensus coordinates:

Rasmol PDB

Jmol PDB

Number of loops: 13

Average sequence ID (%) : 10.7 +/- 13.2
Average RMSD (Å) : 0.931 +/- 0.144

Consensus geometry

d (Å): 9

delta (°): 45-90

theta (°): 135-180

rho (°): 90-135

Consensus Sequence:	ppXXXX
(φψ)-conformation:	aapabb

Pattern:	[FILMVW]	x	[adekqrt]	x	[afglv]	x	[CDENRST]	x	[dehps]	[filtvy]	x	x	x
Conservation:	1.548	-1.424	-0.132	-1.312	-0.218	0.088	0.779	-0.552	1.130	0.547	-1.201	1.261	-0.515

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1bs0_A_286	1bs0	A	302	313	FRAGVQDLPFTL.	HHHHHTTSS-EE.	aaaaaaababbb.
1d3v_A_36	1d3v	A	36	48	LVEKLKETEYNVR	HHHHHTTSSS-EE	aaaaaaaxaxxbb
1dlj_A_330	1dlj	A	334	346	VIDILKSKDIKII	HHHHHHTSS-EEE	aaaaaaababxbb
1ejx_C_1173	1ejx	C	1180	1192	MLQAADSLPVNIG	HHHHHTTSSSEEE	aaaaaaababxbb
1gvh_A_305	1gvh	A	308	320	VKELGQSLPRFTA	HHHHHHTSSSEEE	aaaaaaaxabbbb
1h4p_A_309	1h4p	A	319	331	WGTGVLNESHWIV	HHHHHTT-SSEEE	aaaaaaaxabxbb
1iic_A_269	1iic	A	276	287	FKRYQSRFELIQ.	HHHHHTTSSEEE.	aaaaaaaxabbb.
1iwe_A_46	1iwe	A	50	62	VDLLATDADIVSR	HHHHHTT-SEEEE	aaaaaaaxabbbb
1iyk_A_275	1iyk	A	282	294	LYKYQERFDIVQL	HHHHHTTSSEEEE	aaaaaaaxabbxb
1oao_A_360	1oao	A	360	372	ISAVAECYHTRII	HHHHHTTSS-EEE	aaaaaaabapxxb
1one_A_303	1one	A	306	318	WSHFFKTAGIQIV	HHHHHTT--SEEE	aaaaaaaxabpbx
1ozh_A_38	1ozh	A	40	52	VFDSLLDSSIRII	HHHHGGGSSSEEE	aaaaaaabaxxxb
2nac_A_82	2nac	A	83	95	FERELVDADVVIS	HHHHHTT-SEEEE	aaaaaaaxabbbb

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1h4p_A_309	1h4p	A	NAGN-ACETYL-D-GLUCOSAMINE	G - 322
1h4p_A_309	1h4p	A	NAGN-ACETYL-D-GLUCOSAMINE	N - 325
1h4p_A_309	1h4p	A	GOLGLYCEROL	E - 326
1h4p_A_309	1h4p	A	NAGN-ACETYL-D-GLUCOSAMINE	E - 326
1h4p_A_309	1h4p	A	GOLGLYCEROL	S - 327
1h4p_A_309	1h4p	A	NAGN-ACETYL-D-GLUCOSAMINE	S - 327
1h4p_A_309	1h4p	A	GOLGLYCEROL	H - 328
1h4p_A_309	1h4p	A	GOLGLYCEROL	W - 329
1h4p_A_309	1h4p	A	GOLGLYCEROL	E - 334
1iwe_A_46	1iwe	A	ACTACETATE ION	K - 46
1iwe_A_46	1iwe	A	IMPINOSINIC ACID	K - 46
1iwe_A_46	1iwe	A	ACTACETATE ION	G - 47
1oao_A_360	1oao	A	GOLGLYCEROL	A - 362
1oao_A_360	1oao	A	GOLGLYCEROL	V - 363
1oao_A_360	1oao	A	GOLGLYCEROL	C - 366

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1h4p_A_309	1h4p	A	CC2NAG BINDING SITE FOR CHAIN A	N - 325
1h4p_A_309	1h4p	A	AC5GOL BINDING SITE FOR CHAIN A	S - 327
1h4p_A_309	1h4p	A	AC1GOL BINDING SITE FOR CHAIN A	H - 328
1h4p_A_309	1h4p	A	AC1GOL BINDING SITE FOR CHAIN A	W - 329
1oao_A_360	1oao	A	BC3GOL BINDING SITE FOR CHAIN A	A - 362

Clusters included in this Subclass

CLUSTER: HE.3.164

CLUSTER: HE.4.88

CLUSTER: HE.5.83

CLUSTER: HE.6.249