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Information on SUBCLASS 2.2.21
Subclass Accession number: 8220
Subclass: 2.2.21 PSSM
Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 4.1 (>50 %)  
GO : GO:0016830 (>50 %)  
 Number of loops: 3

Average sequence ID (%) : 28.2 +/- 18.6
Average RMSD (Å) : 0.767 +/- 0.115

Consensus geometry
d (Å): 11 delta (°): 45-90 theta (°): 90-135 rho (°): 0-45
Consensus Sequence: KphDhh
(φψ)-conformation: aapabb
Pattern: xx[AD][ALM][LY][K][QY][AF][D][AV][ILV][RST][FLM]
Conservation:-1.003-1.215-0.258-0.5790.2871.6820.080-0.5672.318-0.1360.198-0.650-0.155
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1ax4_A_2461ax4   A250262IFDMYKYADALTMHHHHGGG-SEEEEaaaaaaababbbb
1knw_A_331knw   A3951QIAALKQFDVVRFHHHTTTTSSEEEEaaaaaaaxabbbx
2dld_A_1932dld   A193205LDDLYKQADVISLHHHHTTT-SEEEEaaaaaaNxabbbx
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1ax4_A_2461ax4   A     LLP2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE) M - 262
1ax4_A_2461ax4   A     LLP2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE) S - 263
1knw_A_331knw   A     PLPPYRIDOXAL-5'-PHOSPHATE A - 52
2dld_A_1932dld   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 205
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1ax4_A_2461ax4   A LPAPYRIDOXAL 5-PHOSPHATE BINDING SITE.S - 263

Clusters included in this Subclass
CLUSTER: HE.5.281