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Information on SUBCLASS 3.2.3
Subclass Accession number: 8307
Subclass: 3.2.3 PSSM
Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 35

Average sequence ID (%) : 13.3 +/- 15.6
Average RMSD (Å) : 0.729 +/- 0.202

Consensus geometry
d (Å): 11 delta (°): 90-135 theta (°): 90-135 rho (°): 315-360
Consensus Sequence: XXphpXh
(φψ)-conformation: aalpabb
Pattern: xx[afgilmvwy][acfilmv][adeknqrst]xx[degknqrs][acilpvy][dehkpqrst]x[acfilmv][afilmvy]
Conservation:-1.162-1.133-0.3070.9060.467-0.457-1.1401.0820.5000.736-1.5751.2750.808
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a05_A_871a05   A92104LRLRKGLDLYANLHHHHHHHT--EEEaaaaaaalxabxb
1bjt_*_7001bjt   -707719LYGCFKKNLKSELHHHHHHT--S-EEaaaaaaalxabxb
1bxk_A_631bxk   A6779ARVFTEHQPDCVMHHHHHHH--SEEEaaaaaaalxabbb
1cnz_A_921cnz   A96108LPLRKHFKLFSNLHHHHHHHT--EEEaaaaaaalxabbb
1db3_A_671db3   A7183TRILREVQPDEVYHHHHHHH--SEEEaaaaaaalxabbb
1e5d_A_881e5d   A89101PALIEACQPEKIFHHHHHHH--SEEEaaaaaaalxabbx
1e6u_A_441e6u   A4860HDFFASERIDQVYHHHHHHH--SEEEaaaaaaalxabbb
1ekj_A_1971ekj   A204216EYAVLHLKVSNIVHHHHHTS--SEEEaaaaaaavpabbb
1fmt_A_711fmt   A7486QQLVAELQADVMVHHHHHHTT-SEEEaaaaaaalxabbx
1gpm_A_431gpm   A4355EAQIRDFNPSGIIHHHHHHH--SEEEaaaaaaalxabbb
1hjr_A_401hjr   A5264TEIITQFQPDYFAHHHHHHH--SEEEaaaaaaavxabbb
1hp1_A_981hp1   A101113FRGMNLVGYDAMAHHHHHHHT--EEEaaaaaaavxabbx
1hvx_A_2091hvx   A220232KWYVNTTNIDGFRHHHHHHH---EEEaaaaaaavxabbb
1i24_A_791i24   A8395AESFKSFEPDSVVHHHHHHH--SEEEaaaaaaalxabbb
1k4g_A_561k4g   A5668PETVRATGADIILHHHHHHTT-S-EEaaaaaaagxabbb
1kht_A_1071kht   A107119SWVLNELNPDLIIHHHHHHH--SEEEaaaaaaalxabbb
1ki9_A_1071ki9   A107119VWVLNELNPDIIIHHHHHHH--SEEEaaaaaaalxabbb
1lc5_A_851lc5   A90102FTVASGLKPRRAMHHHHHHH--SEEEaaaaaaalxabbb
1lci_*_1111lci   -115127LNSMNISQPTVVFHHHHHHH--SEEEaaaaaaalxabbx
1lyv_A_2671lyv   A271283FRMLAENRTPVLAHHHHHHTT-S-EEaaaaaaalpwbbb
1mxi_A_631mxi   A6476EAFLESEKPKRLFHHHHHHH--SEEEaaaaaaalpabbb
1n7h_A_951n7h   A99111RRWIDVIKPDEVYHHHHHHH--SEEEaaaaaaalxabbb
1nks_A_1081nks   A108120SYVITEINPSVIFHHHHHHH--SEEEaaaaaaalxabbx
1nrz_A_161nrz   A2032TVWSKVANAQRIIHHHHHHHT-SEEEaaaaaaalxabxb
1orr_A_621orr   A6678TRLITKYMPDSCFHHHHHHH--SEEEaaaaaaalxabbb
1pb1_A_1141pb1   A116128VALRQELDLYICLHHHHHHTT--EEEaaaaaaalxabbb
1pj3_A_3771pj3   A378390EDAVNILKPSTIIHHHHHHH--SEEEaaaaaaalxabbb
1pox_A_131pox   A1830IKVLEAWGVDHLYHHHHHHTT--EEEaaaaaaavxabbb
1qht_A_1871qht   A195207LRVVREKDPDVLIHHHHHHH--SEEEaaaaaaalxabbb
1qjc_A_741qjc   A7587ANFARNQHATVLIHHHHHHTT--EEEaaaaaaalxabbx
1qv9_A_571qv9   A5769LDIAEDFEPDFIVHHHHHHH--SEEEaaaaaaalxabbb
1qw9_A_541qw9   A5769IELVKELQVPIIRHHHHHHHT--EEEaaaaaaalxwbbx
1xva_A_421xva   A4961LGLLRQHGCHRVLHHHHHHTT--EEEaaaaaaavxaxbb
2aaa_*_1812aaa   -192204ADLVSNYSVDGLRHHHHHHHT--EEEaaaaaaalxabbb
2ayq_A_892ayq   A93105LGLRKEMGLFANLHHHHHHHT--EEEaaaaaaavxaxbx
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1a05_A_871a05   A     IPM3-ISOPROPYLMALIC ACID E - 88
1a05_A_871a05   A     IPM3-ISOPROPYLMALIC ACID L - 91
1a05_A_871a05   A     IPM3-ISOPROPYLMALIC ACID L - 92
1a05_A_871a05   A     IPM3-ISOPROPYLMALIC ACID R - 95
1a05_A_871a05   A     IPM3-ISOPROPYLMALIC ACID R - 105
1a05_A_871a05   A     MGMAGNESIUM ION R - 105
1bxk_A_631bxk   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE H - 80
1cnz_A_921cnz   A     MNMANGANESE (II) ION R - 109
1e6u_A_441e6u   A     NAPNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE L - 61
1ekj_A_1971ekj   A     ACTACETATE ION Y - 205
1ekj_A_1971ekj   A     ACTACETATE ION L - 210
1ekj_A_1971ekj   A     ACTACETATE ION H - 220
1ekj_A_1971ekj   A     ZNZINC ION H - 220
1i24_A_791i24   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE H - 96
1k4g_A_561k4g   A     AIQ2,6-DIAMINO-8-(1H-IMIDAZOL-2-YLSULFANYLMETHYL)-3H-QUINAZOLINE-4-ONE L - 68
1lc5_A_851lc5   A     PIHYDROGENPHOSPHATE ION E - 85
1lc5_A_851lc5   A     PIHYDROGENPHOSPHATE ION T - 86
1lc5_A_851lc5   A     PIHYDROGENPHOSPHATE ION E - 87
1mxi_A_631mxi   A     SAHS-ADENOSYL-L-HOMOCYSTEINE A - 77
1mxi_A_631mxi   A     SAHS-ADENOSYL-L-HOMOCYSTEINE L - 78
1n7h_A_951n7h   A     NDPNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE N - 112
1orr_A_621orr   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE H - 79
1pb1_A_1141pb1   A     ICIISOCITRIC ACID L - 114
1pb1_A_1141pb1   A     ICIISOCITRIC ACID N - 115
1pb1_A_1141pb1   A     ICIISOCITRIC ACID V - 116
1pb1_A_1141pb1   A     ICIISOCITRIC ACID R - 119
1pb1_A_1141pb1   A     GOLGLYCEROL I - 126
1pb1_A_1141pb1   A     ICIISOCITRIC ACID C - 127
1pb1_A_1141pb1   A     GOLGLYCEROL L - 128
1pb1_A_1141pb1   A     ICIISOCITRIC ACID R - 129
1pj3_A_3771pj3   A     MSESELENOMETHIONINE V - 381
1pj3_A_3771pj3   A     MSESELENOMETHIONINE K - 385
1pj3_A_3771pj3   A     MSESELENOMETHIONINE P - 386
1pj3_A_3771pj3   A     MSESELENOMETHIONINE S - 387
1pj3_A_3771pj3   A     MSESELENOMETHIONINE T - 388
1pj3_A_3771pj3   A     MSESELENOMETHIONINE I - 389
1pj3_A_3771pj3   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE G - 391
1qv9_A_571qv9   A     MSESELENOMETHIONINE L - 57
1qv9_A_571qv9   A     MSESELENOMETHIONINE D - 58
1qv9_A_571qv9   A     MSESELENOMETHIONINE I - 59
1qv9_A_571qv9   A     MSESELENOMETHIONINE A - 60
1qv9_A_571qv9   A     MSESELENOMETHIONINE V - 69
1qv9_A_571qv9   A     MSESELENOMETHIONINE Y - 70
1qv9_A_571qv9   A     MSESELENOMETHIONINE G - 71
1qw9_A_541qw9   A     KHP2-HYDROXYMETHYL-5-(4-NITRO-PHENOXY)-TETRAHYDRO-FURAN-3,4-DIOL R - 69
1xva_A_421xva   A     SAMS-ADENOSYLMETHIONINE Y - 44
1xva_A_421xva   A     SAMS-ADENOSYLMETHIONINE D - 62
2aaa_*_1812aaa   *     CACALCIUM ION R - 204

Clusters included in this Subclass
CLUSTER: HE.2.22
CLUSTER: HE.3.18
CLUSTER: HE.4.21
CLUSTER: HE.5.247