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Information on SUBCLASS 4.2.1
Subclass Accession number: 8417
Subclass: 4.2.1 PSSM
Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 26

Average sequence ID (%) : 15.1 +/- 17.8
Average RMSD (Å) : 0.696 +/- 0.178

Consensus geometry
d (Å): 11 delta (°): 90-135 theta (°): 135-180 rho (°): 180-225
Consensus Sequence: pXcXhpXh
(φψ)-conformation: aalababb
Pattern: [adeknqrst][agilmy][ACILMPV][adekqrs][adegknqrst][GKNRS][adegkrs]xxx[ACFILMTV]
Conservation:-0.1840.1001.4900.414-1.0361.792-1.352-0.503-0.342-0.9010.522
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1chr_A_1431chr   A152162EMIERRRHNRFHHHHTT---EEaaaaalabFbb
1chr_A_2511chr   A256266DLARDRSVDVFHHHTTTS-SEEaaaaalababb
1e3i_A_3571e3i   A362372DLMKEGKSIRTHHHHTT--SEEaaaaavababb
1e5m_A_1691e5m   A179189RLVQNGYAKAMHHHHTTS-SEEaaaaavababb
1ezi_A_311ezi   A3848AAISSKCFDRIHHHHH---SEEaaaaavababb
1ga6_A_1121ga6   A120130QAVSDNVAKVIHHHHH---SEEaaaaalaxabb
1hnj_A_1141hnj   A124134QYVKSGAVKYAHHHHTTS-SEEaaaaavababb
1ht0_A_3551ht0   A360370DLLRSGKSIRTHHHHHT--SEEaaaaavababb
1hzp_A_1141hzp   A124134DMIRGGGAATMHHHHTTS-SEEaaaaavababb
1i1q_A_2421i1q   A254264KAIRAGEIFQVHHHHTTS-SEEaaaaavababb
1i7q_A_2421i7q   A254264EAIRQGEIFQVHHHHHTS-SEEaaaaavababb
1kas_*_1651kas   -175185RIIAYGDADVMHHHHHTS-SEEaaaaagababb
1mdl_*_2521mdl   -257267KALSIGACRLAHHHHTT--SEEaaaaavababb
1muc_A_1471muc   A156166HMLEIRRHRVFHHHHTTS-SEEaaaaalababb
1muc_A_2551muc   A260270SLAADGAASIFHHHHHT--SEEaaaaavababb
1mxa_*_2701mxa   -284294NIVAAGLADRCHHHHTTS-SEEaaaaavababb
1n8k_A_3551n8k   A360370DLLRSGESIRTHHHHTT--SEEaaaaavababx
1o63_A_1351o63   A135145LAPIAGLSDLIHHHHHTS-SEEaaaaavababb
1one_A_3271one   A332342TAIEKKAADALHHHHHT--SEEaaaaalababb
1pdz_*_3261pdz   -331341TAVEKKACKCLHHHHTT--SEEaaaaalababb
1ps9_A_2921ps9   A297307DILSRGDADMVHHHHTTS-SEEaaaaavababb
1qdl_A_1571qdl   A169179EYIRSGYIFQVHHHHHTS-SEEaaaaagababb
1rvv_1_591rvv   16575KMAETKKYDAIHHHHTS--SEEaaaaavababb
2hvm_*_162hvm   -1828QTCSTRKYSYVHHHHTS--SEEaaaaavababb
3bam_A_1173bam   A129139LGLKHGEIDLAHHHHTTS-SEEaaaaalababb
3pmg_A_3583pmg   A363373NLMDASKLSLCHHHHTT--SEEaaaaavababb
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1chr_A_1431chr   A     MNMANGANESE (II) ION K - 163
1chr_A_1431chr   A     MNMANGANESE (II) ION K - 165
1chr_A_2511chr   A     MNMANGANESE (II) ION S - 267
1e3i_A_3571e3i   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE M - 364
1e3i_A_3571e3i   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE S - 369
1e3i_A_3571e3i   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 370
1e3i_A_3571e3i   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE R - 371
1e3i_A_3571e3i   A     ZNZINC ION R - 371
1ezi_A_311ezi   A     MSESELENOMETHIONINE L - 31
1ezi_A_311ezi   A     MSESELENOMETHIONINE H - 34
1ga6_A_1121ga6   A     GOLGLYCEROL N - 125
1ga6_A_1121ga6   A     GOLGLYCEROL V - 126
1ga6_A_1121ga6   A     GOLGLYCEROL A - 127
1ga6_A_1121ga6   A     ACTACETATE ION K - 128
1ga6_A_1121ga6   A     GOLGLYCEROL K - 128
1ga6_A_1121ga6   A     ACTACETATE ION V - 132
1ht0_A_3551ht0   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE L - 362
1ht0_A_3551ht0   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE G - 365
1ht0_A_3551ht0   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE S - 367
1ht0_A_3551ht0   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE I - 368
1ht0_A_3551ht0   A     ZNZINC ION R - 369
1ht0_A_3551ht0   A     NADNICOTINAMIDE-ADENINE-DINUCLEOTIDE R - 369
1hzp_A_1141hzp   A     GOLGLYCEROL K - 141
1i7q_A_2421i7q   A     ILGGLUTAMYL GROUP Q - 258
1i7q_A_2421i7q   A     ILGGLUTAMYL GROUP G - 259
1i7q_A_2421i7q   A     ILGGLUTAMYL GROUP E - 260
1i7q_A_2421i7q   A     ILGGLUTAMYL GROUP F - 262
1i7q_A_2421i7q   A     BEZBENZOIC ACID Q - 263
1muc_A_1471muc   A     MNMANGANESE (II) ION K - 167
1muc_A_2551muc   A     MNMANGANESE (II) ION A - 271
1mxa_*_2701mxa   *     PO4PHOSPHATE ION D - 271
1mxa_*_2701mxa   *     POPPYROPHOSPHATE 2- D - 271
1mxa_*_2701mxa   *     MGMAGNESIUM ION D - 271
1n8k_A_3551n8k   A     NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM) L - 362
1n8k_A_3551n8k   A     NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM) S - 367
1n8k_A_3551n8k   A     NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM) I - 368
1n8k_A_3551n8k   A     NAJNICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM) R - 369
1o63_A_1351o63   A     MSESELENOMETHIONINE L - 135
1o63_A_1351o63   A     MSESELENOMETHIONINE V - 146
1one_A_3271one   A     MGMAGNESIUM ION L - 343
1one_A_3271one   A     PEPPHOSPHOENOLPYRUVATE L - 343
1one_A_3271one   A     PAG2-PHOSPHO-D-GLYCERIC ACID L - 343
1pdz_*_3261pdz   *     PGA2-PHOSPHOGLYCOLIC ACID L - 342
1pdz_*_3261pdz   *     MNMANGANESE (II) ION L - 342
1ps9_A_2921ps9   A     FMNFLAVIN MONONUCLEOTIDE S - 308
1ps9_A_2921ps9   A     FMNFLAVIN MONONUCLEOTIDE M - 309
1rvv_1_591rvv   1     INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE I - 59
1rvv_1_591rvv   1     INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE G - 79
1rvv_1_591rvv   1     INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE T - 80
1rvv_1_591rvv   1     INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE V - 81
1rvv_1_591rvv   1     INI5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE I - 82
1rvv_1_591rvv   1     PO4PHOSPHATE ION I - 82
3bam_A_1173bam   A     MNMANGANESE (II) ION S - 123
3bam_A_1173bam   A     MNMANGANESE (II) ION K - 126

Clusters included in this Subclass
CLUSTER: HE.3.176
CLUSTER: HE.4.243
CLUSTER: HE.4.58
CLUSTER: HE.5.48
CLUSTER: HE.6.96