ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.25.2

Subclass Accession number: 8487
Subclass: 4.25.2

Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Conserved Annotation
EC : 1.15 (>75 %)  1.15.1 (>75 %)  1.15.1.1 (>75 %)
GO : GO:0004784 (>75 %)  GO:0016721 (>75 %)
SCOP : 54718 (>75 %)  54719 (>75 %)  54720 (>75 %)

Number of loops: 4

Average sequence ID (%) : 24.2 +/- 25.1
Average RMSD (Å) : 0.775 +/- 0.427

Consensus geometry

d (Å): 11

delta (°): 45-90

theta (°): 135-180

rho (°): 45-90

Consensus Sequence:	XXhpGphh
(φψ)-conformation:	aappepbb

Pattern:	[FR]	x	[EKR]	x	[AKR]	[AEK]	[EMQ]	[FL]	x	[AKQT]	[ATV]	x	x	x	[AMTV]	[EFKQ]	[G]	[ST]	[GP]	[WY]	[AGI]	[AVWY]
Conservation:	0.012	-0.472	0.344	0.217	-0.126	-0.171	-0.105	0.755	-0.622	-0.699	-0.292	-0.541	-0.853	-0.891	-0.583	-0.776	2.498	0.522	0.409	2.901	-0.792	-0.737

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1dt0_A_103	1dt0	A	103	124	FDKFKEEFTKTSVGTFGSGWGW	HHHHHHHHHHHHHT--SSEEEE	aaaaaaaaaaaaaaxxexbbbb
1ids_A_106	1ids	A	106	127	FDKFRAQFHAAATTVQGSGWAA	HHHHHHHHHHHHH--SSSEEEE	aaaaaaaaaaaaaaxbexebbb
1ma1_A_112	1ma1	A	112	133	FERFRKEFSQAAISAEGSGWAV	HHHHHHHHHHHHHT-SSSEEEE	aaaaaaaaaaaaaapxexebbb
1uok_*_344	1uok	-	344	365	RIESAKMLATVLHMMKGTPYIY	HHHHHHHHHHHHHTSSSEEEEE	aaaaaaaaaaaaaaxxexxbbx

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1dt0_A_103	1dt0	A	FEFE (III) ION	W - 122
1ids_A_106	1ids	A	FEFE (III) ION	W - 125
1ma1_A_112	1ma1	A	OF1FERROUS ION, 1 WATER COORDINATED	W - 131

Clusters included in this Subclass

CLUSTER: HE.4.227