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Information on SUBCLASS 4.27.2
Subclass Accession number: 8492
Subclass: 4.27.2 PSSM
Type: HE alpha-beta
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB

Conserved Annotation
EC : 1.1 (>75 %)  1.1.1 (>75 %)  
SCOP : 51734 (>75 %)  51735 (>75 %)  51848 (>75 %)  
 Number of loops: 5

Average sequence ID (%) : 26.7 +/- 28.6
Average RMSD (Å) : 1.140 +/- 0.152

Consensus geometry
d (Å): 11 delta (°): 90-135 theta (°): 135-180 rho (°): 135-180
Consensus Sequence: phXhhXLX
(φψ)-conformation: aalpaapa
Pattern: [GKQ][AIV]x[DEHQS][EG][AV][aclm]x[EL][AIL][DEGQ][DHT]x[AKL][FLY][GP][kl][L]x[ADEG][FIMV][sty]x[dgt]
Conservation:-0.0620.290-0.213-0.0920.8201.282-0.8160.755-0.3110.002-0.2350.256-0.016-0.8060.6401.419-1.0352.985-1.370-0.6800.424-1.072-1.183-0.982
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1b8p_A_471b8p   A5174KALQGVMMEIDDCAFPLLAGMTAHHHHHHHHHHHHTTT-TTEEEEEEEaaaaaaaaaaaaalxaaxaebbbb
1gpu_A_1631gpu   A163186GISSEASSLAGHLKLGNLIAIYDDHHHHHHHHHHHHTT-TTEEEEEEEaaaaaaaaaaaaalxaaxbbbxxx
1qgd_A_1611qgd   A161184GISHEVCSLAGTLKLGKLIAFYDDHHHHHHHHHHHHTT-TTEEEEEEEaaaaaaaaaaaaalxaaxbbbbxx
5mdh_A_465mdh   A4770GVLDGVLMELQDCALPLLKDVIATHHHHHHHHHHHHT--TTEEEEEEEaaaaaaaaaaaaavbaaxabbbbb
7mdh_A_897mdh   A90113QALEGVAMELEDSLYPLLREVSIGHHHHHHHHHHHTTT-TTEEEEEEEaaaaaaaaaaaaalxaaxabbbbe
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1gpu_A_1631gpu   A     CACALCIUM ION D - 185
1gpu_A_1631gpu   A     THD2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE D - 185
1gpu_A_1631gpu   A     CACALCIUM ION D - 186
1qgd_A_1611qgd   A     CACALCIUM ION D - 183
1qgd_A_1611qgd   A     TPPTHIAMINE DIPHOSPHATE D - 183

Clusters included in this Subclass
CLUSTER: HE.6.73