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Information on SUBCLASS 1.2.4
Subclass Accession number: 8826
Subclass: 1.2.4 PSSM
Type: HH alpha-alpha
DB: ArchDB-EC

Image coordinates: Rasmol PDB Jmol PDB
Consensus coordinates: Rasmol PDB Jmol PDB
Number of loops: 14

Average sequence ID (%) : 14.2 +/- 15.2
Average RMSD (Å) : 0.600 +/- 0.184

Consensus geometry
d (Å): 9 delta (°): 90-135 theta (°): 90-135 rho (°): 135-180
Consensus Sequence: XXcXp
(φψ)-conformation: aabaa
Pattern: x[afiklmv]x[aekrs][DEKNQ][apstv][denrs][fiklv][acfgilpv][adekqrst][ekqrst][AFILMY]
Conservation:-0.530-0.642-1.296-0.3592.4870.2010.2090.395-0.990-0.4360.0080.951
Loops included in this Subclass
LoopPDBChainStartEndSequenceSec StructRamachandran
1a53_*_2341a53   -235246SLMRNPEKIKEFHHHH-TTHHHHHaaaabaaaaaaa
1a79_A_711a79   A7889ARNVEERLCLKYHHHH-TTHHHHHaaaabaaaaaaa
1ep3_A_2721ep3   A272283ANFADPFVCPKIHHHH-TTHHHHHaaaabaaaaaaa
1ez0_A_2641ez0   A266277AMRAKADLADQFHHHH-TTHHHHHaaaabaaaaaaa
1f7l_A_121f7l   A1829MAGRQKRFAERIHHHH-TTHHHHHaaaabaaaaaaa
1gwu_A_141gwu   A2536ELRSDPRIAASIHHHH-TTHHHHHaaaabaaaaaaa
1jku_A_881jku   A90101DLKRDPSLATTMHHHH-TTHHHHHaaaabaaaaaaa
1jqo_A_7941jqo   A801812AIDKDVRNFQVLHHHH-TTHHHHHaaaabaaaaaaa
1oya_*_3481oya   -349360FFISNPDLVDRLHHHH-TTHHHHHaaaabaaaaaaa
1pa2_A_141pa2   A2536ALQSDTRIGASLHHTT-TTHHHHHaaaabaaaaaaa
1pmi_*_2321pmi   -235246FKDIDSRLPELIHHTT-TTHHHHHaaaabaaaaaaa
1ps9_A_3121ps9   A312323PFLADAELLSKAHHHH-TTHHHHHaaaabaaaaaaa
1qo2_A_1031qo2   A104115KVLEDPSFLKSLHHHH-TTHHHHHaaaabaaaaaaa
1rlv_A_2021rlv   A209220AREVERNFDRRYHHHHSTTHHHHHaaaaxaaaaaaa
PDB ligands within a cut-off distance of 6 Å in this subclass
LoopPDBChainLigandsResidue
1a53_*_2341a53   *     IGPINDOLE-3-GLYCEROL PHOSPHATE S - 234
1a53_*_2341a53   *     IGPINDOLE-3-GLYCEROL PHOSPHATE S - 235
1a79_A_711a79   A     AUGOLD ION Y - 75
1a79_A_711a79   A     AUGOLD ION R - 79
1a79_A_711a79   A     AUGOLD ION L - 85
1a79_A_711a79   A     AUGOLD ION C - 86
1a79_A_711a79   A     AUGOLD ION L - 87
1a79_A_711a79   A     AUGOLD ION Y - 89
1a79_A_711a79   A     AUGOLD ION L - 90
1ep3_A_2721ep3   A     FMNFLAVIN MONONUCLEOTIDE A - 272
1ep3_A_2721ep3   A     FMNFLAVIN MONONUCLEOTIDE F - 274
1f7l_A_121f7l   A     CACALCIUM ION R - 14
1gwu_A_141gwu   A     HEMPROTOPORPHYRIN IX CONTAINING FE R - 31
1gwu_A_141gwu   A     CACALCIUM ION R - 31
1gwu_A_141gwu   A     HEMPROTOPORPHYRIN IX CONTAINING FE A - 33
1gwu_A_141gwu   A     HEMPROTOPORPHYRIN IX CONTAINING FE A - 34
1gwu_A_141gwu   A     CACALCIUM ION A - 34
1gwu_A_141gwu   A     HEMPROTOPORPHYRIN IX CONTAINING FE S - 35
1gwu_A_141gwu   A     CACALCIUM ION S - 35
1gwu_A_141gwu   A     HEMPROTOPORPHYRIN IX CONTAINING FE I - 36
1gwu_A_141gwu   A     HEMPROTOPORPHYRIN IX CONTAINING FE L - 37
1gwu_A_141gwu   A     CACALCIUM ION L - 37
1gwu_A_141gwu   A     HEMPROTOPORPHYRIN IX CONTAINING FE R - 38
1gwu_A_141gwu   A     CACALCIUM ION R - 38
1gwu_A_141gwu   A     ACTACETATE ION R - 38
1gwu_A_141gwu   A     HEMPROTOPORPHYRIN IX CONTAINING FE F - 41
1gwu_A_141gwu   A     CACALCIUM ION F - 41
1gwu_A_141gwu   A     ACTACETATE ION F - 41
1gwu_A_141gwu   A     HEMPROTOPORPHYRIN IX CONTAINING FE H - 42
1gwu_A_141gwu   A     CACALCIUM ION H - 42
1gwu_A_141gwu   A     ACTACETATE ION H - 42
1gwu_A_141gwu   A     CACALCIUM ION D - 43
1gwu_A_141gwu   A     CACALCIUM ION C - 44
1oya_*_3481oya   *     FMNFLAVIN MONONUCLEOTIDE R - 348
1oya_*_3481oya   *     FMNFLAVIN MONONUCLEOTIDE F - 349
1oya_*_3481oya   *     FMNFLAVIN MONONUCLEOTIDE I - 351
1pa2_A_141pa2   A     HEMPROTOPORPHYRIN IX CONTAINING FE G - 33
1pa2_A_141pa2   A     HEMPROTOPORPHYRIN IX CONTAINING FE L - 36
1pa2_A_141pa2   A     CACALCIUM ION I - 37
1pa2_A_141pa2   A     HEMPROTOPORPHYRIN IX CONTAINING FE I - 37
1ps9_A_3121ps9   A     FS4IRON/SULFUR CLUSTER P - 312
1ps9_A_3121ps9   A     FMNFLAVIN MONONUCLEOTIDE P - 312
1ps9_A_3121ps9   A     FS4IRON/SULFUR CLUSTER L - 314
1ps9_A_3121ps9   A     FMNFLAVIN MONONUCLEOTIDE L - 314
1ps9_A_3121ps9   A     FS4IRON/SULFUR CLUSTER A - 315
PDB Site Annotated loops in this subclass
LoopPDBChainSiteResidue
1gwu_A_141gwu   A HEMHEM BINDING SITE FOR CHAIN AR - 31
1gwu_A_141gwu   A HEMHEM BINDING SITE FOR CHAIN AA - 34
1gwu_A_141gwu   A HEMHEM BINDING SITE FOR CHAIN AS - 35
1gwu_A_141gwu   A HEMHEM BINDING SITE FOR CHAIN AR - 38
1gwu_A_141gwu   A HEMHEM BINDING SITE FOR CHAIN AF - 41
1gwu_A_141gwu   A AC1ACT BINDING SITE FOR CHAIN AH - 42
1gwu_A_141gwu   A CA1CA BINDING SITE FOR CHAIN AD - 43

Clusters included in this Subclass
CLUSTER: HH.2.132
CLUSTER: HH.2.64
CLUSTER: HH.3.81
CLUSTER: HH.4.27