ArchDB - Biological DataBase of Protein Loops

Information on SUBCLASS 4.21.1

Subclass Accession number: 9070
Subclass: 4.21.1

Type: HH alpha-alpha
DB: ArchDB-EC

Image coordinates:

Consensus coordinates:

Number of loops: 5

Average sequence ID (%) : 40.7 +/- 28.3
Average RMSD (Å) : 0.340 +/- 0.114

Consensus geometry

d (Å): 15

delta (°): 0-45

theta (°): 45-90

rho (°): 0-45

Consensus Sequence:	XXhEGppp
(φψ)-conformation:	aaplMpaa

Pattern:	[AIV]	[AEP]	[KNR]	[HILY]	[MY]	[r]	[DT]	[AF]	[KRT]	[IP]	[ty]	[CEQ]	[IT]	[FY]	[EG]	[G]	[ET]	[ANS]	[EQT]	[IV]	[MQ]	x	[ILM]	[iv]	[ITV]	[AG]	[GR]	[aef]	[HL]
Conservation:	-0.041	-0.748	0.194	-0.975	0.402	-0.674	0.548	-0.456	-0.158	-0.737	-0.927	-0.700	-0.176	2.529	0.147	3.307	0.186	-0.204	-0.207	1.205	0.566	-0.692	0.561	-0.699	-0.250	0.370	-0.257	-1.478	-0.633

Loops included in this Subclass

Loop	PDB	Chain	Start	End	Sequence	Sec Struct	Ramachandran
1buc_A_353	1buc	A	353	381	VARHMRDAKITQIYEGTNEVQLMVTGGAL	HHHHHHHHGGGGTTTS-HHHHHHHHHHHH	aaaaaaaaaaaaaxvepaaaaaaaaaaaa
1egd_A_362	1egd	A	362	390	VEKLMRDAKIYQIYGGTSQIQRLIVAREH	HHHHHHHHGGGGTTTS-HHHHHHHHHHHH	aaaaaaaaaaaaaxvMpaaaaaaaaaaaa
1is2_A_407	1is2	A	407	435	IPNIYVTFTPACTFEGENTVMMLQTARFL	HHHHHHHHGGGGTTTS-HHHHHHHHHHHH	aaaaaaaaaaaaaxlMpaaaaaaaaaaaa
1jqi_A_354	1jqi	A	354	382	AERYYRDARITEIYEGTSEIQRLVIAGHL	HHHHHHHHGGGGTTTS-HHHHHHHHHHHH	aaaaaaaaaaaaaxvexaaaaaaaaaaaa
1udy_A_362	1udy	A	362	390	VEKLMRDAKIYQIYEGTAQIQRIIIAREH	HHHHHHHHGGGGTSSS-HHHHHHHHHHHH	aaaaaaaaaaaaaxvMxaaaaaaaaaaaa

PDB ligands within a cut-off distance of 6 Å in this subclass

Loop	PDB	Chain	Ligands	Residue
1buc_A_353	1buc	A	FADFLAVIN-ADENINE DINUCLEOTIDE	I - 362
1buc_A_353	1buc	A	FADFLAVIN-ADENINE DINUCLEOTIDE	I - 365
1buc_A_353	1buc	A	CAAACETOACETYL-COENZYME A	I - 365
1buc_A_353	1buc	A	FADFLAVIN-ADENINE DINUCLEOTIDE	Y - 366
1buc_A_353	1buc	A	CAAACETOACETYL-COENZYME A	Y - 366
1buc_A_353	1buc	A	FADFLAVIN-ADENINE DINUCLEOTIDE	E - 367
1buc_A_353	1buc	A	CAAACETOACETYL-COENZYME A	E - 367
1buc_A_353	1buc	A	FADFLAVIN-ADENINE DINUCLEOTIDE	G - 368
1buc_A_353	1buc	A	CAAACETOACETYL-COENZYME A	G - 368
1buc_A_353	1buc	A	FADFLAVIN-ADENINE DINUCLEOTIDE	T - 369
1buc_A_353	1buc	A	CAAACETOACETYL-COENZYME A	T - 369
1buc_A_353	1buc	A	FADFLAVIN-ADENINE DINUCLEOTIDE	N - 370
1buc_A_353	1buc	A	FADFLAVIN-ADENINE DINUCLEOTIDE	E - 371
1buc_A_353	1buc	A	FADFLAVIN-ADENINE DINUCLEOTIDE	V - 372
1buc_A_353	1buc	A	CAAACETOACETYL-COENZYME A	V - 372
1buc_A_353	1buc	A	FADFLAVIN-ADENINE DINUCLEOTIDE	M - 375
1buc_A_353	1buc	A	CAAACETOACETYL-COENZYME A	M - 375
1buc_A_353	1buc	A	CAAACETOACETYL-COENZYME A	V - 376
1egd_A_362	1egd	A	FADFLAVIN-ADENINE DINUCLEOTIDE	I - 371
1egd_A_362	1egd	A	FADFLAVIN-ADENINE DINUCLEOTIDE	I - 374
1egd_A_362	1egd	A	FADFLAVIN-ADENINE DINUCLEOTIDE	Y - 375
1egd_A_362	1egd	A	FADFLAVIN-ADENINE DINUCLEOTIDE	G - 376
1egd_A_362	1egd	A	FADFLAVIN-ADENINE DINUCLEOTIDE	G - 377
1egd_A_362	1egd	A	FADFLAVIN-ADENINE DINUCLEOTIDE	T - 378
1egd_A_362	1egd	A	FADFLAVIN-ADENINE DINUCLEOTIDE	S - 379
1egd_A_362	1egd	A	FADFLAVIN-ADENINE DINUCLEOTIDE	Q - 380
1egd_A_362	1egd	A	FADFLAVIN-ADENINE DINUCLEOTIDE	I - 381
1egd_A_362	1egd	A	FADFLAVIN-ADENINE DINUCLEOTIDE	L - 384
1is2_A_407	1is2	A	FADFLAVIN-ADENINE DINUCLEOTIDE	P - 416
1is2_A_407	1is2	A	FADFLAVIN-ADENINE DINUCLEOTIDE	T - 419
1is2_A_407	1is2	A	FADFLAVIN-ADENINE DINUCLEOTIDE	F - 420
1is2_A_407	1is2	A	FADFLAVIN-ADENINE DINUCLEOTIDE	G - 422
1is2_A_407	1is2	A	FADFLAVIN-ADENINE DINUCLEOTIDE	E - 423
1is2_A_407	1is2	A	FADFLAVIN-ADENINE DINUCLEOTIDE	N - 424
1is2_A_407	1is2	A	FADFLAVIN-ADENINE DINUCLEOTIDE	T - 425
1is2_A_407	1is2	A	FADFLAVIN-ADENINE DINUCLEOTIDE	V - 426
1is2_A_407	1is2	A	FADFLAVIN-ADENINE DINUCLEOTIDE	L - 429
1jqi_A_354	1jqi	A	FADFLAVIN-ADENINE DINUCLEOTIDE	I - 363
1jqi_A_354	1jqi	A	CAAACETOACETYL-COENZYME A	I - 366
1jqi_A_354	1jqi	A	FADFLAVIN-ADENINE DINUCLEOTIDE	I - 366
1jqi_A_354	1jqi	A	CAAACETOACETYL-COENZYME A	Y - 367
1jqi_A_354	1jqi	A	FADFLAVIN-ADENINE DINUCLEOTIDE	Y - 367
1jqi_A_354	1jqi	A	CAAACETOACETYL-COENZYME A	E - 368
1jqi_A_354	1jqi	A	FADFLAVIN-ADENINE DINUCLEOTIDE	E - 368
1jqi_A_354	1jqi	A	CAAACETOACETYL-COENZYME A	G - 369
1jqi_A_354	1jqi	A	FADFLAVIN-ADENINE DINUCLEOTIDE	G - 369
1jqi_A_354	1jqi	A	CAAACETOACETYL-COENZYME A	T - 370
1jqi_A_354	1jqi	A	FADFLAVIN-ADENINE DINUCLEOTIDE	T - 370
1jqi_A_354	1jqi	A	FADFLAVIN-ADENINE DINUCLEOTIDE	S - 371
1jqi_A_354	1jqi	A	FADFLAVIN-ADENINE DINUCLEOTIDE	E - 372
1jqi_A_354	1jqi	A	CAAACETOACETYL-COENZYME A	I - 373
1jqi_A_354	1jqi	A	FADFLAVIN-ADENINE DINUCLEOTIDE	I - 373
1jqi_A_354	1jqi	A	CAAACETOACETYL-COENZYME A	Q - 374
1jqi_A_354	1jqi	A	CAAACETOACETYL-COENZYME A	L - 376
1jqi_A_354	1jqi	A	FADFLAVIN-ADENINE DINUCLEOTIDE	L - 376
1jqi_A_354	1jqi	A	CAAACETOACETYL-COENZYME A	V - 377
1jqi_A_354	1jqi	A	CAAACETOACETYL-COENZYME A	H - 381
1jqi_A_354	1jqi	A	CAAACETOACETYL-COENZYME A	R - 384
1udy_A_362	1udy	A	CS83-THIAOCTANOYL-COENZYME A	I - 374
1udy_A_362	1udy	A	CS83-THIAOCTANOYL-COENZYME A	Y - 375
1udy_A_362	1udy	A	FADFLAVIN-ADENINE DINUCLEOTIDE	E - 376
1udy_A_362	1udy	A	CS83-THIAOCTANOYL-COENZYME A	E - 376
1udy_A_362	1udy	A	CS83-THIAOCTANOYL-COENZYME A	G - 377
1udy_A_362	1udy	A	CS83-THIAOCTANOYL-COENZYME A	T - 378
1udy_A_362	1udy	A	FADFLAVIN-ADENINE DINUCLEOTIDE	A - 379
1udy_A_362	1udy	A	CS83-THIAOCTANOYL-COENZYME A	I - 381
1udy_A_362	1udy	A	FADFLAVIN-ADENINE DINUCLEOTIDE	I - 384
1udy_A_362	1udy	A	CS83-THIAOCTANOYL-COENZYME A	I - 384
1udy_A_362	1udy	A	CS83-THIAOCTANOYL-COENZYME A	I - 385
1udy_A_362	1udy	A	CS83-THIAOCTANOYL-COENZYME A	R - 388
1udy_A_362	1udy	A	CS83-THIAOCTANOYL-COENZYME A	E - 389

PDB Site Annotated loops in this subclass

Loop	PDB	Chain	Site	Residue
1egd_A_362	1egd	A	CA1CATALYTIC BASE IN CHAIN A	G - 376

Clusters included in this Subclass

CLUSTER: HH.8.9