| Accession | HsInv0856 | Region of the inversion | chr11:1866125-1925182 |
| Status | Predicted | Prediction type | Simple |
| Estimated Inversion Size | 46,035 bp | Supporting predictions | 6 |
| Inverted allele frequency | ND | Mechanism of origin | ND |
| Functional effect | Intergenic breakpoints | Breakpoint 1 | chr11:1866125-1879676 |
| Ancestral orientation | NA | Breakpoint 2 | chr11:1912687-1925182 |
|
|
 |
|
|
Human Polymorphic Inversion DataBase
|
General information
- Region map
+ Predictions
| Description | Next generation sequencing and analysis by paired-end mapping of an individual genome of African origin | ||||||||||||||||||
| Method | Paired-end mapping (PEM) | ||||||||||||||||||
| Name | |||||||
| Breakpoint 1 | chr11:1870776-1871185 | Breakpoint 2 | chr11:1917433-1917668 | ||||
| Individuals |
| ||||||
| Comments | Prediction within region overlapping more than 90% of their length with simple repeats, low complexity repeats, or satellite repeats | ||||||
| Description | Paired-end mapping of 3-kb fragments in an African and in a putatively European individual with some predictions validated by PCR, fiber-FISH or comparison with Celera assembly | ||||||||||||||||||||||||||||||||||
| Method | Paired-end mapping (PEM) | ||||||||||||||||||||||||||||||||||
| Name | |||||||||
| Breakpoint 1 | chr11:1872866-1872866 | Breakpoint 2 | chr11:1919497-1919497 | ||||||
| Individuals |
| ||||||||
| Name | |||||||||
| Breakpoint 1 | chr11:1872935-1872935 | Breakpoint 2 | chr11:1918372-1918372 | ||||||
| Individuals |
| ||||||||
- Martinez-Fundichely et al. 2014 (in preparation)
| Description | Accurate prediction of inversions in the human genome from Kidd et al. 2008 fosmid paired-end mapping data using the GRIAL algorithm, and validation of some predictions by sequence analysis and PCR | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Method | Paired-end mapping (PEM) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Name | |||||||||||||||||||||||
| Breakpoint 1 | chr11:1873181-1878178 | Breakpoint 2 | chr11:1898344-1922007 | ||||||||||||||||||||
| D/C Score | 0.31 | Disc. Support Prob. | 0.05431 | ||||||||||||||||||||
| Support | 74 probes  | ||||||||||||||||||||||
| Individuals |
| ||||||||||||||||||||||
| Name | |||||||||||||||||||||||
| Breakpoint 1 | chr11:1880497-1893541 | Breakpoint 2 | chr11:1905660-1938898 | ||||||||||||||||||||
| D/C Score | -1.92 | Disc. Support Prob. | 0.00247 | ||||||||||||||||||||
| Support | 24 probes | ||||||||||||||||||||||
| Individuals |
| ||||||||||||||||||||||
| Name | |||||||||||||||||||||||
| Breakpoint 1 | chr11:1850614-1872337 | Breakpoint 2 | chr11:1907411-1932600 | ||||||||||||||||||||
| D/C Score | 1.11 | Disc. Support Prob. | 0.00229 | ||||||||||||||||||||
| Support | 122 probes | ||||||||||||||||||||||
| Individuals |
| ||||||||||||||||||||||
+ Validation and genotyping
No validations are found
+ Frequency
No frequency studied
+ Breakpoints
| Breakpoint 1 | chr11:1866125-1879676 | Breakpoint 2 | chr11:1912687-1925182 | ||
| Description | Breakpoints calculated without considering unreliable predictions | ||||
| Definition method | Default informatic definition | ||||
| Mechanism of origin |
ND
|
||||
| Flexibility | 11.04 | GC content | 0.31 | Stability | 1.81 |
+ Evolutionary history
| Ancestral allele | NA | Age | ND |
| Derived allele | NA | Origin | ND |
+ Orientation in other species
Not defined
+ Age
Not defined
+ Origin
Not defined
+ Functional effects
No genes disrupted by the inversion breakpoints
+ Inversion phenotypical effects
Not defined
+ Report history
- 2015-02-23 10:14:38
| Breakpoint 1 | chr11:1866125-1879676 | Breakpoint 2 | chr11:1912687-1925182 |
| Assembly | hg18 | ||
| Description | Breakpoints calculated without considering unreliable predictions | ||
| Definition method | Default informatic definition | ||
- 2015-02-23 10:14:38
| Breakpoint 1 | chr11:1866125-1876337 | Breakpoint 2 | chr11:1912687-1922994 |
| Assembly | hg18 | ||
| Definition method | Default informatic definition | ||
