hmmpfam - search one or more sequences against HMM database HMMER 2.2g (August 2001) Copyright (C) 1992-2001 HHMI/Washington University School of Medicine Freely distributed under the GNU General Public License (GPL) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: myhmms Sequence file: 7LES_DROME - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query sequence: 7LES_DROME Accession: P13368 Description: SEVENLESS PROTEIN (EC 2.7.1.112). Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- pkinase 304.1 1.1e-91 1 fn3 176.3 3.5e-53 6 rrm -44.5 4 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- fn3 1/6 437 522 .. 1 84 [] 49.0 7.1e-15 fn3 2/6 825 914 .. 1 84 [] 13.6 0.00033 fn3 3/6 1292 1389 .. 1 84 [] 16.2 5.3e-05 rrm 1/1 1300 1364 .. 1 72 [] -44.5 4 fn3 4/6 1799 1891 .. 1 84 [] 63.5 3.2e-19 fn3 5/6 1899 1978 .. 1 84 [] 14.6 0.00016 fn3 6/6 1993 2107 .. 1 84 [] 19.4 5.9e-06 pkinase 1/1 2209 2483 .. 1 278 [] 304.1 1.1e-91 Alignments of top-scoring domains: fn3: domain 1 of 6, from 437 to 522: score 49.0, E = 7.1e-15 *->P.saPtnltvtdvtstsltlsWsppt.gngpitgYevtyRqpkngge P saP + +++ ++ l ++W p + ngpi+gY+++ ++++g+ 7LES_DROME 437 PiSAPVIEHLMGLDDSHLAVHWHPGRfTNGPIEGYRLRL-SSSEGNA 482 wneltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* + e+ vp+ sy+++ L++gt+Yt+ + +n +G+Gp 7LES_DROME 483 TSEQLVPAGRGSYIFSQLQAGTNYTLALSMINKQGeGPVA 522 fn3: domain 2 of 6, from 825 to 914: score 13.6, E = 0.00033 *->PsaPtnltvtdvtstsltlsWsppt.......gngpitgYevtyRqp ++P l++ ++ + +sW+ p++++ ++ + + +Ye+++ + 7LES_DROME 825 GGKPHSLKALL-GAQAAKISWKEPErnpyqsaDAARSWSYELEV-LD 869 knggewnelt.vpgtttsytltgLkPgteYtvrVqAvnggG..GpeS<-* + +++ ++++++ g+ + l+ L+P+ Y++rV+A+n +G++G+++ 7LES_DROME 870 VASQSAFSIRnIRGPI--FGLQRLQPDNLYQLRVRAINVDGepGEWT 914 fn3: domain 3 of 6, from 1292 to 1389: score 16.2, E = 5.3e-05 *->PsaPtnltv......tdv..tstsltlsWsppt....gngpitgYev Ps+P++l+v ++ t++++ s++l+W++p+++++ Y + 7LES_DROME 1292 PSQPRRLRVfverlaTALqeANVSAVLRWDAPEqgqeAPMQALEYHI 1338 tyRqpknggewneltvpgttt.sytltgLkPgteYtvrVqAvnggG.... ++ + ++ +e+ +++ ++ ++ L+P+ +Y+++V A+ ++++ 7LES_DROME 1339 SC-WVGSEL--HEELRLNQSAlEARVEHLQPDQTYHFQVEARVAATgaaa 1385 GpeS<-* G++S 7LES_DROME 1386 GAAS 1389 rrm: domain 1 of 1, from 1300 to 1364: score -44.5, E = 4 *->lfVgNLppdtteeeLkdlFsqfGpiksikvikDreTgrskGfaFVeF +fV L + e + + + p + +++ e+ 7LES_DROME 1300 VFVERLATALQEANVSAVLRWDAPEQGQEAPMQ----------ALEY 1336 ede....edAekAidalnGkelgGrklrv<-* + + +++ + ++ ln l+ r+ + 7LES_DROME 1337 HIScwvgSELHEELR-LNQSALEARVEHL 1364 fn3: domain 4 of 6, from 1799 to 1891: score 63.5, E = 3.2e-19 *->PsaPtnltvtdvtstsltlsWsppt.gngpitgYevtyRqpkngge. Ps+P+n++v+ +++ +l +sW pp++ +++ +Y++++ q++ +ge+ 7LES_DROME 1799 PSPPRNFSVRVLSPRELEVSWLPPEqLRSESVYYTLHW-QQELDGEn 1844 .......wneltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* +++++ + +++ t+ ++ ltg kPg+ Y+++VqA+ + +++ S 7LES_DROME 1845 vqdrrewEAHERRLETAGTHRLTGIKPGSGYSLWVQAHATPTkSNSS 1891 fn3: domain 5 of 6, from 1899 to 1978: score 14.6, E = 0.00016 *->PsaPtnltvtdvtstsltlsWspptgngpitgYevtyRqpknggewn + l+ +++++sl+l+W p+ + ++++R ++ e 7LES_DROME 1899 FAELPELQLLELGPYSLSLTWAGT--PDPLGSLQLECR---SSAEQL 1940 eltvpgtttsytltgLkPgteYtvrVqAvnggG.GpeS<-* +++v g+ t ++++ L+P t+Y+ r+ +++++G++ 7LES_DROME 1941 RRNVAGNHTKMVVEPLQPRTRYQCRLLLGYAATpGAPL 1978 fn3: domain 6 of 6, from 1993 to 2107: score 19.4, E = 5.9e-06 *->PsaPtnltvtdvtstsltlsWsppt.gngpitgYevtyRqpkngge. Ps+P+ ++ + + + ++++W++++++++pi Y+++ ++++ + 7LES_DROME 1993 PSQPGKPQLEHIAEEVFRVTWTAARgNGAPIALYNLEA-LQARSDIr 2038 ...........................wneltvpgttt.sytltgLkPgt +++++++++++++ ++ + +++ ++++l+ +tt s++++ L + 7LES_DROME 2039 rrrrrrrrnsggsleqlpwaeepvvveDQWLDFCNTTElSCIVKSLHSSR 2088 eYtvrVqAvn.ggG.GpeS<-* +rV+A++ ++G Gp+S 7LES_DROME 2089 LLLFRVRARSlEHGwGPYS 2107 pkinase: domain 1 of 1, from 2209 to 2483: score 304.1, E = 1.1e-91 *->yelleklGeGsfGkVykakhk.....tgkivAvKilk..kesls..l ++ll+ lG+G+fG+Vy++++k+++++ ++vA+K l+++++++ + l 7LES_DROME 2209 LKLLRFLGSGAFGEVYEGQLKtedseEPQRVAIKSLRkgASEFAelL 2255 rEiqilkrlsHpNIvrllgvfedtddhlylvmEymegGdLfdylrrng.. E+q++ +++H+NIvrl g++ + +++ l+mE+me GdL++ylr+ + + 7LES_DROME 2256 QEAQLMSNFKHENIVRLVGICF-DTESISLIMEHMEAGDLLSYLRAARat 2304 .........plsekeakkialQilrGleYLHsngivHRDLKpeNILlden ++++++++ ls e++ ++ ++++G +YL+++++vHRDL+ +N+L++e 7LES_DROME 2305 stqepqptaGLSLSELLAMCIDVANGCSYLEDMHFVHRDLACRNCLVTES 2354 .......gtvKiaDFGLArll.....eklttfvGTpwYmmAPEvilegrg +++++++ tvKi+DFGLAr++ +++ +++ + + p+++m+PE l + 7LES_DROME 2355 tgstdrrRTVKIGDFGLARDIyksdyYRKEGEGLLPVRWMSPES-LVDGL 2403 ysskvDvWSlGviLyElltggplfpgadlpaftggdevdqliifvlklPf +++++DvW++Gv+++E+lt g ++P+ 7LES_DROME 2404 FTTQSDVWAFGVLCWEILTLG-------------------------QQPY 2428 sdelpktridpleelfrikkr.rlplpsncSeelkdLlkkcLnkDPskRp +++e l k+++rl +p+ c e l++Ll c++ DP++Rp 7LES_DROME 2429 AA------RNNFEVLAHVKEGgRLQQPPMCTEKLYSLLLLCWRTDPWERP 2472 Gsatakeilnhpwf<-* +++ + n + 7LES_DROME 2473 ---SFRRCYNTLHA 2483 //