PDB: 1ak2 Compound: adenylate kinase isoenzyme-2 Classification: PHOSPHOTRANSFERASE Entry date in PDB: 1996-06-10 Resolution [Å]: 1.92 R-Factor: 0.222

CHAIN: - SWISS-PROT/TREMBL: P08166    KEYWORD: 3D-structure    Alternative splicing    ATP-binding    Kinase    Mitochondrion    Transferase    EC: 2.7.4.3 SCOP: c.37.1.1 Alpha and beta proteins (a/b)    P-loop containing nucleoside triphosphate hydrolases    P-loop containing nucleoside triphosphate hydrolases    Nucleotide and nucleoside kinases    Adenylate kinase    Cow (Bos taurus), mitochondrial izozyme-2 SCOP: c.37.1.1 Alpha and beta proteins (a/b)    P-loop containing nucleoside triphosphate hydrolases    P-loop containing nucleoside triphosphate hydrolases    Nucleotide and nucleoside kinases    Adenylate kinase    Cow (Bos taurus), mitochondrial izozyme-2 SCOP: g.41.2.1 Small proteins    Rubredoxin-like    Microbial and mitochondrial ADK, insert "zinc finger" domain    Microbial and mitochondrial ADK, insert "zinc finger" domain    Microbial and mitochondrial ADK, insert "zinc finger" domain    Cow (Bos taurus), mitochondrial izozyme-2 GO:  adenylate kinase activity    ATP binding    nucleotide kinase activity    phosphotransferase activity, phosphate group as acceptor    nucleobase, nucleoside, nucleotide and nucleic acid metabolism

Image Source: PDB

Loops in ArchDB95 clusters

1ak2_*_208 - EH => SUBCLASS : 4.2.3
1ak2_*_18 - EH => SUBCLASS : 5.5.1
1ak2_*_152 - AR => SUBCLASS : 18.2.1
1ak2_*_47 - HH => SUBCLASS : 2.2.4
1ak2_*_60 - HH => SUBCLASS : 5.4.1
1ak2_*_29 - HE => SUBCLASS : 1.2.2
1ak2_*_29 - HE => SUBCLASS : 1.2.3
1ak2_*_29 - HE => SUBCLASS : 1.2.4
1ak2_*_133 - HE => SUBCLASS : 1.3.4
1ak2_*_106 - HE => SUBCLASS : 5.3.2
1ak2_*_77 - HE => SUBCLASS : 7.9.1
1ak2_*_144 - HA => SUBCLASS : 4.1.1

Loops in ArchDB-EC clusters

1ak2_*_60 - HH => SUBCLASS : 5.1.2

Loops in ArchDB-KI clusters

1ak2_*_43 - EH => SUBCLASS : 0.1.1
1ak2_*_125 - EH => SUBCLASS : 1.1.1
1ak2_*_208 - EH => SUBCLASS : 4.1.1
1ak2_*_97 - EH => SUBCLASS : 5.1.1
1ak2_*_18 - EH => SUBCLASS : 6.1.1
1ak2_*_144 - HA => SUBCLASS : 4.1.1
1ak2_*_133 - HE => SUBCLASS : 1.2.1
1ak2_*_29 - HE => SUBCLASS : 2.1.1
1ak2_*_181 - HE => SUBCLASS : 2.4.2
1ak2_*_106 - HE => SUBCLASS : 5.1.1
1ak2_*_77 - HE => SUBCLASS : 7.1.1
1ak2_*_60 - HH => SUBCLASS : 5.1.1

Loops not clustered in ArchDB

1ak2_*_152 - AR
1ak2_*_43 - EH
1ak2_*_97 - EH
1ak2_*_125 - EH
1ak2_*_174 - EH
1ak2_*_144 - HA
1ak2_*_181 - HE

Loops not clustered in ArchDB-KI

1ak2_*_152 - AR
1ak2_*_174 - EH
1ak2_*_47 - HH

2ak2 - - percentage of sequence identity: 100
2c9y A - percentage of sequence identity: 93