PDB: 1df7 Compound: dihydrofolate reductase Classification: OXIDOREDUCTASE Entry date in PDB: 2000-03-09 Resolution [Å]: 1.70 R-Factor: 0.187

CHAIN: A SWISS-PROT/TREMBL: O33305    KEYWORD: 3D-structure    Complete proteome    NADP    One-carbon metabolism    Oxidoreductase    EC: 1.5.1.3 SCOP: c.71.1.1 Alpha and beta proteins (a/b)    Dihydrofolate reductases    Dihydrofolate reductases    Dihydrofolate reductases    Dihydrofolate reductase, prokaryotic type    Mycobacterium tuberculosis GO:  dihydrofolate reductase activity    glycine biosynthesis    nucleotide biosynthesis

Image Source: PDB

Loops in ArchDB40 clusters

1df7_A_97 - HE => SUBCLASS : 2.3.2
1df7_A_25 - HE => SUBCLASS : 2.7.2
1df7_A_44 - HE => SUBCLASS : 10.1.1
1df7_A_143 - HA => SUBCLASS : 3.1.1
1df7_A_2 - HA => SUBCLASS : 3.1.2
1df7_A_143 - HA => SUBCLASS : 5.3.2
1df7_A_13 - EH => SUBCLASS : 8.7.1

Loops in ArchDB95 clusters

1df7_A_77 - EH => SUBCLASS : 2.1.7
1df7_A_77 - EH => SUBCLASS : 2.1.14
1df7_A_13 - EH => SUBCLASS : 8.28.1
1df7_A_97 - HE => SUBCLASS : 2.2.7
1df7_A_25 - HE => SUBCLASS : 3.8.2
1df7_A_44 - HE => SUBCLASS : 10.5.1
1df7_A_143 - HA => SUBCLASS : 3.1.1
1df7_A_143 - HA => SUBCLASS : 4.3.2

Loops in ArchDB-EC clusters

1df7_A_44 - HE => SUBCLASS : 10.3.1

Loops not clustered in ArchDB

1df7_A_136 - AR
1df7_A_136 - AR
1df7_A_126 - AR
1df7_A_109 - AR
1df7_A_109 - AR
1df7_A_126 - AR
1df7_A_39 - EH
1df7_A_91 - EH
1df7_A_2 - HA
1df7_A_61 - HA
1df7_A_61 - HA
1df7_A_143 - HA
1df7_A_82 - HE

1dg5 A - percentage of sequence identity: 100
1dg7 A - percentage of sequence identity: 100
1dg8 A - percentage of sequence identity: 100