PDB: 1eak Compound: 72 kda type iv collagenase Classification: HYDROLYSE Entry date in PDB: 2002-08-22 Resolution [Å]: 2.66 R-Factor: 0.271

CHAIN: A SWISS-PROT/TREMBL: P08253    KEYWORD: 3D-structure    Calcium-binding    Collagen degradation    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Repeat    Signal    Zinc    Zymogen    EC: 3.4.24.24 SCOP: a.20.1.2 All alpha proteins    PGBD-like    PGBD-like    MMP N-terminal domain    Gelatinase A (MMP-2)    Human (Homo sapiens) SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Gelatinase A    Human (Homo sapiens) SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Gelatinase A    Human (Homo sapiens) SCOP: g.14.1.2 Small proteins    Kringle-like    Kringle-like    Fibronectin type II module    Gelatinase A (MMP-2) type II modules    Human (Homo sapiens) SCOP: g.14.1.2 Small proteins    Kringle-like    Kringle-like    Fibronectin type II module    Gelatinase A (MMP-2) type II modules    Human (Homo sapiens) SCOP: g.14.1.2 Small proteins    Kringle-like    Kringle-like    Fibronectin type II module    Gelatinase A (MMP-2) type II modules    Human (Homo sapiens) GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: P08253    KEYWORD: 3D-structure    Calcium-binding    Collagen degradation    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Repeat    Signal    Zinc    Zymogen    EC: 3.4.24.24 SCOP: a.20.1.2 All alpha proteins    PGBD-like    PGBD-like    MMP N-terminal domain    Gelatinase A (MMP-2)    Human (Homo sapiens) SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Gelatinase A    Human (Homo sapiens) SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Gelatinase A    Human (Homo sapiens) SCOP: g.14.1.2 Small proteins    Kringle-like    Kringle-like    Fibronectin type II module    Gelatinase A (MMP-2) type II modules    Human (Homo sapiens) SCOP: g.14.1.2 Small proteins    Kringle-like    Kringle-like    Fibronectin type II module    Gelatinase A (MMP-2) type II modules    Human (Homo sapiens) SCOP: g.14.1.2 Small proteins    Kringle-like    Kringle-like    Fibronectin type II module    Gelatinase A (MMP-2) type II modules    Human (Homo sapiens) GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis    CHAIN: C SWISS-PROT/TREMBL: P08253    KEYWORD: 3D-structure    Calcium-binding    Collagen degradation    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Repeat    Signal    Zinc    Zymogen    EC: 3.4.24.24 SCOP: a.20.1.2 All alpha proteins    PGBD-like    PGBD-like    MMP N-terminal domain    Gelatinase A (MMP-2)    Human (Homo sapiens) SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Gelatinase A    Human (Homo sapiens) SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Gelatinase A    Human (Homo sapiens) SCOP: g.14.1.2 Small proteins    Kringle-like    Kringle-like    Fibronectin type II module    Gelatinase A (MMP-2) type II modules    Human (Homo sapiens) SCOP: g.14.1.2 Small proteins    Kringle-like    Kringle-like    Fibronectin type II module    Gelatinase A (MMP-2) type II modules    Human (Homo sapiens) SCOP: g.14.1.2 Small proteins    Kringle-like    Kringle-like    Fibronectin type II module    Gelatinase A (MMP-2) type II modules    Human (Homo sapiens) GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis    CHAIN: D SWISS-PROT/TREMBL: P08253    KEYWORD: 3D-structure    Calcium-binding    Collagen degradation    Extracellular matrix    Glycoprotein    Hydrolase    Metal-binding    Metalloprotease    Repeat    Signal    Zinc    Zymogen    EC: 3.4.24.24 SCOP: a.20.1.2 All alpha proteins    PGBD-like    PGBD-like    MMP N-terminal domain    Gelatinase A (MMP-2)    Human (Homo sapiens) SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Gelatinase A    Human (Homo sapiens) SCOP: d.92.1.11 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Matrix metalloproteases, catalytic domain    Gelatinase A    Human (Homo sapiens) SCOP: g.14.1.2 Small proteins    Kringle-like    Kringle-like    Fibronectin type II module    Gelatinase A (MMP-2) type II modules    Human (Homo sapiens) SCOP: g.14.1.2 Small proteins    Kringle-like    Kringle-like    Fibronectin type II module    Gelatinase A (MMP-2) type II modules    Human (Homo sapiens) SCOP: g.14.1.2 Small proteins    Kringle-like    Kringle-like    Fibronectin type II module    Gelatinase A (MMP-2) type II modules    Human (Homo sapiens) GO:  extracellular matrix (sensu Metazoa)    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis

Image Source: PDB

1qib A - percentage of sequence identity: 83
830c A - percentage of sequence identity: 61