PDB: 1iae Compound: Astacin with zinc replaced by nickel(ii) Classification: ZINC ENDOPEPTIDASE Entry date in PDB: 1994-08-31 Resolution [Å]: 1.83 R-Factor: 0.143

CHAIN: - SWISS-PROT/TREMBL: P07584    KEYWORD: 3D-structure    Hydrolase    Metalloprotease    Signal    Zinc    Zymogen    EC: 3.4.24.21 SCOP: d.92.1.8 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Astacin    Astacin    European fresh water crayfish (Astacus astacus) GO:  astacin activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB40 clusters

1iae_*_24 - HE => SUBCLASS : 2.5.1
1iae_*_24 - HE => SUBCLASS : 3.8.2
1iae_*_14 - EH => SUBCLASS : 3.4.1

Loops in ArchDB95 clusters

1iae_*_14 - EH => SUBCLASS : 3.6.1
1iae_*_24 - HE => SUBCLASS : 2.2.2

Loops not clustered in ArchDB

1iae_*_2 - AR
1iae_*_134 - AR
1iae_*_113 - AR
1iae_*_54 - AR
1iae_*_44 - AR
1iae_*_74 - EH
1iae_*_164 - EH
1iae_*_64 - HA
1iae_*_87 - HE
1iae_*_184 - HH

1ast - - percentage of sequence identity: 100
1iaa - - percentage of sequence identity: 100
1iac - - percentage of sequence identity: 100
1iad - - percentage of sequence identity: 100
1qji A - percentage of sequence identity: 100
1qjj A - percentage of sequence identity: 100