PDB: 1j8u Compound: phenylalanine-4-hydroxylase Classification: OXIDOREDUCTASE Entry date in PDB: 2002-05-22 Resolution [Å]: 1.50 R-Factor: 0.157

CHAIN: A SWISS-PROT/TREMBL: P00439    KEYWORD: 3D-structure    Allosteric enzyme    Disease mutation    Iron    Monooxygenase    Oxidoreductase    Phenylalanine catabolism    Phenylketonuria    Phosphorylation    Polymorphism    EC: 1.14.16.1 SCOP: d.178.1.1 Alpha and beta proteins (a+b)    Aromatic aminoacid monoxygenases, catalytic and oligomerization domains    Aromatic aminoacid monoxygenases, catalytic and oligomerization domains    Aromatic aminoacid monoxygenases, catalytic and oligomerization domains    Phenylalanine hydroxylase, PAH    Human (Homo sapiens) GO:  amino acid binding    iron ion binding    monooxygenase activity    phenylalanine 4-monooxygenase activity    aromatic amino acid family metabolism    L-phenylalanine catabolism    metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1j8u_A_251 - HE => SUBCLASS : 1.1.3
1j8u_A_333 - HA => SUBCLASS : 2.3.1
1j8u_A_412 - HA => SUBCLASS : 4.1.1
1j8u_A_385 - EH => SUBCLASS : 0.1.1
1j8u_A_339 - EH => SUBCLASS : 2.4.5
1j8u_A_363 - EH => SUBCLASS : 3.8.2
1j8u_A_241 - EH => SUBCLASS : 5.3.2
1j8u_A_345 - HH => SUBCLASS : 1.1.2
1j8u_A_291 - HH => SUBCLASS : 1.1.8
1j8u_A_291 - HH => SUBCLASS : 1.1.14
1j8u_A_345 - HH => SUBCLASS : 1.2.2
1j8u_A_181 - HH => SUBCLASS : 2.1.40

Loops in ArchDB95 clusters

1j8u_A_385 - EH => SUBCLASS : 2.1.4
1j8u_A_363 - EH => SUBCLASS : 2.4.13
1j8u_A_363 - EH => SUBCLASS : 3.8.2
1j8u_A_241 - EH => SUBCLASS : 5.4.1
1j8u_A_345 - HH => SUBCLASS : 1.1.1
1j8u_A_291 - HH => SUBCLASS : 1.1.3
1j8u_A_345 - HH => SUBCLASS : 1.1.5
1j8u_A_181 - HH => SUBCLASS : 2.1.1
1j8u_A_297 - HH => SUBCLASS : 4.9.6
1j8u_A_152 - HH => SUBCLASS : 13.5.1
1j8u_A_251 - HE => SUBCLASS : 1.2.1
1j8u_A_351 - HE => SUBCLASS : 4.11.1
1j8u_A_333 - HA => SUBCLASS : 2.3.1
1j8u_A_412 - HA => SUBCLASS : 4.1.1

Loops in ArchDB-EC clusters

1j8u_A_152 - HH => SUBCLASS : 13.1.1

Loops not clustered in ArchDB

1j8u_A_262 - EH
1j8u_A_333 - HA
1j8u_A_412 - HA
1j8u_A_227 - HE
1j8u_A_315 - HE
1j8u_A_369 - HE
1j8u_A_392 - HE
1j8u_A_204 - HH
1j8u_A_283 - HH

1dmw A - percentage of sequence identity: 100
1j8t A - percentage of sequence identity: 100
1kw0 A - percentage of sequence identity: 100
1lrm A - percentage of sequence identity: 100
1mmk A - percentage of sequence identity: 100
1mmt A - percentage of sequence identity: 100
1pah - - percentage of sequence identity: 100
1phz A - percentage of sequence identity: 95
1tdw A - percentage of sequence identity: 99
1tg2 A - percentage of sequence identity: 99
2pah A - percentage of sequence identity: 100
2pah B - percentage of sequence identity: 100
2phm A - percentage of sequence identity: 95
2toh A - percentage of sequence identity: 62
3pah - - percentage of sequence identity: 100
4pah - - percentage of sequence identity: 100
5pah - - percentage of sequence identity: 100
6pah - - percentage of sequence identity: 100