PDB: 1ka9 Compound: imidazole glycerol phosphtate synthase Classification: TRANSFERASE Entry date in PDB: 2002-12-04 Resolution [Å]: 2.30 R-Factor: 0.203

CHAIN: F SWISS-PROT/TREMBL: Q7SIB9    KEYWORD: 3D-structure    Histidine biosynthesis    Lyase    EC: 4.1.3.- SCOP: c.1.2.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Ribulose-phoshate binding barrel    Histidine biosynthesis enzymes    Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF    Thermus thermophilus GO:  cytoplasm    imidazoleglycerol phosphate synthase complex    imidazoleglycerol phosphate synthase activity    histidine biosynthesis    CHAIN: H SWISS-PROT/TREMBL: Q7SIC0    KEYWORD: 3D-structure    Glutamine amidotransferase    Histidine biosynthesis    Transferase    EC: 2.4.2.- SCOP: c.23.16.1 Alpha and beta proteins (a/b)    Flavodoxin-like    Class I glutamine amidotransferase-like    Class I glutamine amidotransferases (GAT)    GAT subunit, HisH, (or domain) of imidazoleglycerolphosphate synthase HisF    Thermus thermophilus GO:  cytoplasm    catalytic activity    transferase activity, transferring pentosyl groups    glutamine metabolism    histidine biosynthesis

Image Source: PDB

Loops in ArchDB40 clusters

1ka9_H_154 - HA => SUBCLASS : 2.1.1
1ka9_H_78 - EH => SUBCLASS : 1.5.1
1ka9_H_172 - EH => SUBCLASS : 3.6.4
1ka9_H_137 - AR => SUBCLASS : 1.1.4

Loops in ArchDB95 clusters

1ka9_H_78 - EH => SUBCLASS : 1.3.3
1ka9_H_172 - EH => SUBCLASS : 3.4.5
1ka9_F_48 - EH => SUBCLASS : 4.6.5
1ka9_F_199 - EH => SUBCLASS : 5.12.1
1ka9_F_168 - EH => SUBCLASS : 11.14.1
1ka9_F_105 - HH => SUBCLASS : 1.2.2
1ka9_F_105 - HH => SUBCLASS : 1.2.6
1ka9_F_226 - HH => SUBCLASS : 4.1.1
1ka9_H_65 - HE => SUBCLASS : 2.1.3
1ka9_H_83 - HE => SUBCLASS : 2.2.4
1ka9_H_154 - HA => SUBCLASS : 2.1.1
1ka9_H_161 - HA => SUBCLASS : 2.5.1
1ka9_F_138 - HA => SUBCLASS : 4.6.1

Loops in ArchDB-EC clusters

1ka9_F_226 - HH => SUBCLASS : 4.1.3

Loops not clustered in ArchDB

1ka9_H_107 - AR
1ka9_H_118 - AR
1ka9_H_125 - AR
1ka9_H_144 - AR
1ka9_H_28 - AR
1ka9_H_107 - AR
1ka9_H_118 - AR
1ka9_H_125 - AR
1ka9_H_137 - AR
1ka9_H_144 - AR
1ka9_H_28 - AR
1ka9_F_17 - EH
1ka9_H_4 - EH
1ka9_F_78 - EH
1ka9_F_100 - EH
1ka9_F_148 - EH
1ka9_F_221 - EH
1ka9_H_43 - EH
1ka9_F_126 - HA
1ka9_F_138 - HA
1ka9_H_91 - HA
1ka9_H_161 - HA
1ka9_H_154 - HA
1ka9_F_6 - HA
1ka9_F_126 - HA
1ka9_H_91 - HA
1ka9_F_6 - HA
1ka9_F_33 - HE
1ka9_F_208 - HE
1ka9_H_15 - HE
1ka9_F_154 - HE
1ka9_F_112 - HE
1ka9_F_87 - HE
1ka9_F_60 - HE
1ka9_F_185 - HE
1ka9_H_52 - HH

1h5y A - percentage of sequence identity: 61