PDB: 1npc Compound: Neutral protease Classification: HYDROLASE(METALLOPROTEINASE) Entry date in PDB: 1993-10-31 Resolution [Å]: 2.00 R-Factor: 0.175

CHAIN: - SWISS-PROT/TREMBL: P05806    KEYWORD: 3D-structure    Calcium-binding    Hydrolase    Metal-binding    Metalloprotease    Signal    Zinc    EC: 3.4.24.28 SCOP: d.92.1.2 Alpha and beta proteins (a+b)    Zincin-like    Metalloproteases ("zincins"), catalytic domain    Thermolysin-like    Neutral protease    Bacillus cereus, strain dsm 3101 GO:  extracellular region    metalloendopeptidase activity    metallopeptidase activity    zinc ion binding    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB95 clusters

1npc_*_62 - EH => SUBCLASS : 2.3.8
1npc_*_121 - EH => SUBCLASS : 14.6.1
1npc_*_282 - HH => SUBCLASS : 4.18.2
1npc_*_69 - HE => SUBCLASS : 11.7.1

Loops in ArchDB-EC clusters

1npc_*_261 - HH => SUBCLASS : 6.1.2

Loops not clustered in ArchDB

1npc_*_101 - AR
1npc_*_101 - AR
1npc_*_57 - AR
1npc_*_54 - AR
1npc_*_57 - AR
1npc_*_54 - AR
1npc_*_204 - EH
1npc_*_254 - EH
1npc_*_17 - HA
1npc_*_28 - HA
1npc_*_32 - HA
1npc_*_40 - HA
1npc_*_114 - HA
1npc_*_188 - HA
1npc_*_4 - HA
1npc_*_249 - HA
1npc_*_188 - HA
1npc_*_4 - HA
1npc_*_17 - HA
1npc_*_28 - HA
1npc_*_32 - HA
1npc_*_40 - HA
1npc_*_114 - HA
1npc_*_249 - HA
1npc_*_226 - HE
1npc_*_160 - HE
1npc_*_138 - HH

1esp - - percentage of sequence identity: 99
1fj3 A - percentage of sequence identity: 73
1fjo A - percentage of sequence identity: 73
1fjq A - percentage of sequence identity: 73
1fjt A - percentage of sequence identity: 73
1fju A - percentage of sequence identity: 73
1fjv A - percentage of sequence identity: 73
1fjw A - percentage of sequence identity: 73
1gxw A - percentage of sequence identity: 73
1hyt - - percentage of sequence identity: 73
1kjp A - percentage of sequence identity: 73
1kkk A - percentage of sequence identity: 73
1kl6 A - percentage of sequence identity: 73
1kr6 A - percentage of sequence identity: 73
1kro A - percentage of sequence identity: 73
1ks7 A - percentage of sequence identity: 73
1kto A - percentage of sequence identity: 73
1l3f E - percentage of sequence identity: 73
1lna E - percentage of sequence identity: 73
1lnb E - percentage of sequence identity: 73
1lnc E - percentage of sequence identity: 73
1lnd E - percentage of sequence identity: 73
1lne E - percentage of sequence identity: 73
1lnf E - percentage of sequence identity: 73
1os0 A - percentage of sequence identity: 73
1pe5 A - percentage of sequence identity: 73
1pe7 A - percentage of sequence identity: 73
1pe8 A - percentage of sequence identity: 73
1qf0 A - percentage of sequence identity: 73
1qf1 A - percentage of sequence identity: 73
1qf2 A - percentage of sequence identity: 73
1thl A - percentage of sequence identity: 73
1tli A - percentage of sequence identity: 73
1tlp E - percentage of sequence identity: 73
1tlx A - percentage of sequence identity: 73
1tmn E - percentage of sequence identity: 73
1trl A - percentage of sequence identity: 67
1trl B - percentage of sequence identity: 67
1y3g E - percentage of sequence identity: 73
1z9g E - percentage of sequence identity: 73
1zdp E - percentage of sequence identity: 73
2a7g E - percentage of sequence identity: 73
2tli A - percentage of sequence identity: 73
2tlx A - percentage of sequence identity: 73
2tmn E - percentage of sequence identity: 73
3tli A - percentage of sequence identity: 73
3tmn E - percentage of sequence identity: 73
4tli A - percentage of sequence identity: 73
4tln - - percentage of sequence identity: 73
4tmn E - percentage of sequence identity: 73
5tli A - percentage of sequence identity: 73
5tln - - percentage of sequence identity: 73
5tmn E - percentage of sequence identity: 73
6tli A - percentage of sequence identity: 73
6tmn E - percentage of sequence identity: 73
7tli A - percentage of sequence identity: 73
7tln - - percentage of sequence identity: 73
8tli A - percentage of sequence identity: 73
8tln E - percentage of sequence identity: 73