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Information on 1pgr
PDB: 1pgr
Compound: granulocyte colony-stimulating factor
Classification: CYTOKINE
Entry date in PDB: 2000-03-08
Resolution [Å]: 3.50
R-Factor: 0.317


CHAIN: B
SWISS-PROT/TREMBL: P40223
   KEYWORD: 3D-structure    Cell adhesion    Glycoprotein    Immunoglobulin domain    Receptor    Repeat    Signal    Transmembrane   
SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Granulocyte colony-stimulating factor (GC-SF) receptor    Mouse (Mus musculus)
SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Granulocyte colony-stimulating factor (GC-SF) receptor    Mouse (Mus musculus)
GO:  membrane    hematopoietin/interferon-class (D200-domain) cytokine receptor activity   


CHAIN: C
SWISS-PROT/TREMBL: P09919
   KEYWORD: 3D-structure    Alternative splicing    Cytokine    Glycoprotein    Growth factor    Pharmaceutical    Polymorphism    Signal   
SCOP: a.26.1.1 All alpha proteins    4-helical cytokines    4-helical cytokines    Long-chain cytokines    Granulocyte-colony stimulating factor (G-CSF)    Human (Homo sapiens)
GO:  extracellular region    cytokine activity    growth factor activity    immune response   


CHAIN: D
SWISS-PROT/TREMBL: P40223
   KEYWORD: 3D-structure    Cell adhesion    Glycoprotein    Immunoglobulin domain    Receptor    Repeat    Signal    Transmembrane   
SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Granulocyte colony-stimulating factor (GC-SF) receptor    Mouse (Mus musculus)
SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Granulocyte colony-stimulating factor (GC-SF) receptor    Mouse (Mus musculus)
GO:  membrane    hematopoietin/interferon-class (D200-domain) cytokine receptor activity   


CHAIN: F
SWISS-PROT/TREMBL: P40223
   KEYWORD: 3D-structure    Cell adhesion    Glycoprotein    Immunoglobulin domain    Receptor    Repeat    Signal    Transmembrane   
SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Granulocyte colony-stimulating factor (GC-SF) receptor    Mouse (Mus musculus)
SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Granulocyte colony-stimulating factor (GC-SF) receptor    Mouse (Mus musculus)
GO:  membrane    hematopoietin/interferon-class (D200-domain) cytokine receptor activity   


CHAIN: G
SWISS-PROT/TREMBL: P09919
   KEYWORD: 3D-structure    Alternative splicing    Cytokine    Glycoprotein    Growth factor    Pharmaceutical    Polymorphism    Signal   
SCOP: a.26.1.1 All alpha proteins    4-helical cytokines    4-helical cytokines    Long-chain cytokines    Granulocyte-colony stimulating factor (G-CSF)    Human (Homo sapiens)
GO:  extracellular region    cytokine activity    growth factor activity    immune response   


CHAIN: H
SWISS-PROT/TREMBL: P40223
   KEYWORD: 3D-structure    Cell adhesion    Glycoprotein    Immunoglobulin domain    Receptor    Repeat    Signal    Transmembrane   
SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Granulocyte colony-stimulating factor (GC-SF) receptor    Mouse (Mus musculus)
SCOP: b.1.2.1 All beta proteins    Immunoglobulin-like beta-sandwich    Fibronectin type III    Fibronectin type III    Granulocyte colony-stimulating factor (GC-SF) receptor    Mouse (Mus musculus)
GO:  membrane    hematopoietin/interferon-class (D200-domain) cytokine receptor activity   
1pgr Image
Image Source: PDB
Homologous structures to 1pgr classified in ArchDB

1bge A - percentage of sequence identity: 80