PDB: 1pyt Compound: procarboxypeptidase a Classification: TERNARY COMPLEX (ZYMOGEN) Entry date in PDB: 1997-01-27 Resolution [Å]: 2.35 R-Factor: 0.192

CHAIN: A SWISS-PROT/TREMBL: P00730    KEYWORD: 3D-structure    Carboxypeptidase    Hydrolase    Metalloprotease    Polymorphism    Signal    Zinc    Zymogen    EC: 3.4.17.1 SCOP: d.58.3.1 Alpha and beta proteins (a+b)    Ferredoxin-like    Protease propeptides/inhibitors    Pancreatic carboxypeptidase, activation domain    Procarboxypeptidase A    Cow (Bos taurus) GO:  carboxypeptidase A activity    carboxypeptidase activity    proteolysis and peptidolysis    CHAIN: B SWISS-PROT/TREMBL: P00730    KEYWORD: 3D-structure    Carboxypeptidase    Hydrolase    Metalloprotease    Polymorphism    Signal    Zinc    Zymogen    EC: 3.4.17.1 SCOP: c.56.5.1 Alpha and beta proteins (a/b)    Phosphorylase/hydrolase-like    Zn-dependent exopeptidases    Pancreatic carboxypeptidases    Carboxypeptidase A    Cow (Bos taurus) GO:  carboxypeptidase A activity    carboxypeptidase activity    proteolysis and peptidolysis    CHAIN: C SWISS-PROT/TREMBL: P05805    KEYWORD: 3D-structure    Digestion    Pancreas    Serine protease homolog    3D-structure    Digestion    Pancreas    Serine protease homolog    SCOP: b.47.1.2 All beta proteins    Trypsin-like serine proteases    Trypsin-like serine proteases    Eukaryotic proteases    Procarboxypeptidase A-S6 subunit III (zymogen E)    Cow (Bos taurus) GO:  chymotrypsin activity    trypsin activity    proteolysis and peptidolysis

Image Source: PDB

Loops in ArchDB95 clusters

1pyt_C_626 - EH => SUBCLASS : 0.1.2
1pyt_A_11 - EH => SUBCLASS : 3.3.1
1pyt_D_859 - EH => SUBCLASS : 3.7.1
1pyt_D_859 - EH => SUBCLASS : 3.7.2
1pyt_D_751 - AR => SUBCLASS : 7.7.1
1pyt_C_504 - AR => SUBCLASS : 26.1.1
1pyt_C_504 - AR => SUBCLASS : 27.1.1
1pyt_A_58 - HE => SUBCLASS : 1.1.1
1pyt_C_607 - HA => SUBCLASS : 11.6.1
1pyt_D_781 - HA => SUBCLASS : 12.1.1
1pyt_C_488 - HA => SUBCLASS : 14.5.1

Loops in ArchDB-EC clusters

1pyt_A_58 - HE => SUBCLASS : 1.1.1

Loops not clustered in ArchDB

1pyt_C_451 - AR
1pyt_C_481 - AR
1pyt_D_880 - AR
1pyt_C_580 - AR
1pyt_D_804 - AR
1pyt_D_926 - EH
1pyt_C_556 - EH
1pyt_A_74 - EH
1pyt_A_52 - EH
1pyt_C_598 - HA
1pyt_A_36 - HA
1pyt_C_535 - HA
1pyt_C_464 - HA
1pyt_C_437 - HA
1pyt_D_730 - HA
1pyt_D_737 - HA
1pyt_D_764 - HA
1pyt_D_835 - HA
1pyt_D_898 - HA
1pyt_D_907 - HA
1pyt_C_430 - HA
1pyt_A_36 - HA
1pyt_A_20 - HE
1pyt_D_865 - HE
1pyt_C_565 - HE

1aye - - percentage of sequence identity: 66
1bru P - percentage of sequence identity: 64
1fon B - percentage of sequence identity: 97
1m4l A - percentage of sequence identity: 99
1pca - - percentage of sequence identity: 87