PDB: 1r3s Compound: uroporphyrinogen decarboxylase Classification: LYASE Entry date in PDB: 2003-12-09 Resolution [Å]: 1.65 R-Factor: 0.163

CHAIN: A SWISS-PROT/TREMBL: P06132    KEYWORD: 3D-structure    Acetylation    Decarboxylase    Disease mutation    Heme biosynthesis    Lyase    Porphyrin biosynthesis    EC: 4.1.1.37 SCOP: c.1.22.1 Alpha and beta proteins (a/b)    TIM beta/alpha-barrel    Uroporphyrinogen decarboxylase, UROD    Uroporphyrinogen decarboxylase, UROD    Uroporphyrinogen decarboxylase, UROD    Human (Homo sapiens) GO:  uroporphyrinogen decarboxylase activity    porphyrin biosynthesis

Image Source: PDB

Loops in ArchDB40 clusters

1r3s_A_99 - HA => SUBCLASS : 3.6.1
1r3s_A_151 - EH => SUBCLASS : 1.1.1
1r3s_A_151 - EH => SUBCLASS : 1.1.9
1r3s_A_279 - EH => SUBCLASS : 5.1.1
1r3s_A_279 - EH => SUBCLASS : 6.2.1
1r3s_A_300 - EH => SUBCLASS : 7.18.1

Loops in ArchDB95 clusters

1r3s_A_151 - EH => SUBCLASS : 1.1.13
1r3s_A_151 - EH => SUBCLASS : 1.1.14
1r3s_A_279 - EH => SUBCLASS : 4.2.4
1r3s_A_279 - EH => SUBCLASS : 5.3.1
1r3s_A_279 - EH => SUBCLASS : 6.2.1
1r3s_A_300 - EH => SUBCLASS : 8.10.1
1r3s_A_185 - HE => SUBCLASS : 3.1.1
1r3s_A_185 - HE => SUBCLASS : 3.1.4
1r3s_A_132 - HE => SUBCLASS : 5.56.1
1r3s_A_99 - HA => SUBCLASS : 3.8.1

Loops in ArchDB-EC clusters

1r3s_A_132 - HE => SUBCLASS : 5.46.1

Loops not clustered in ArchDB

1r3s_A_81 - EH
1r3s_A_105 - EH
1r3s_A_213 - EH
1r3s_A_258 - EH
1r3s_A_333 - EH
1r3s_A_99 - HA
1r3s_A_89 - HE
1r3s_A_288 - HE
1r3s_A_314 - HE
1r3s_A_62 - HE
1r3s_A_269 - HE
1r3s_A_234 - HE
1r3s_A_18 - HH
1r3s_A_55 - HH
1r3s_A_127 - HH
1r3s_A_158 - HH
1r3s_A_175 - HH
1r3s_A_226 - HH
1r3s_A_44 - HH

1jph A - percentage of sequence identity: 99
1jpi A - percentage of sequence identity: 99
1jpk A - percentage of sequence identity: 99
1r3q A - percentage of sequence identity: 99
1r3r A - percentage of sequence identity: 99
1r3t A - percentage of sequence identity: 100
1r3v A - percentage of sequence identity: 99
1r3w A - percentage of sequence identity: 99
1r3y A - percentage of sequence identity: 99
1uro A - percentage of sequence identity: 99