PDB: 1s3i Compound: 10-formyltetrahydrofolate dehydrogenase Classification: HYDROLASE, OXIDOREDUCTASE Entry date in PDB: 2004-01-27 Resolution [Å]: 2.30 R-Factor: 0.245

CHAIN: A SWISS-PROT/TREMBL: P28037    KEYWORD: NADP    One-carbon metabolism    Oxidoreductase    Phosphopantetheine    EC: 1.5.1.6 SCOP: b.46.1.1 All beta proteins    FMT C-terminal domain-like    FMT C-terminal domain-like    Post formyltransferase domain    10-formyltetrahydrofolate dehydrogenase domain 2    Rat (Rattus norvegicus) SCOP: c.65.1.1 Alpha and beta proteins (a/b)    Formyltransferase    Formyltransferase    Formyltransferase    10-formyltetrahydrofolate dehydrogenase domain 2    Rat (Rattus norvegicus) GO:  cytoplasm    cofactor binding    formyltetrahydrofolate dehydrogenase activity    hydroxymethyl-, formyl- and related transferase activity    oxidoreductase activity    10-formyltetrahydrofolate catabolism    biosynthesis    metabolism    one-carbon compound metabolism

Image Source: PDB

Loops in ArchDB40 clusters

1s3i_A_60 - HA => SUBCLASS : 2.1.1
1s3i_A_233 - HA => SUBCLASS : 2.1.1
1s3i_A_271 - HA => SUBCLASS : 2.2.2
1s3i_A_276 - HA => SUBCLASS : 5.1.3
1s3i_A_286 - HA => SUBCLASS : 5.1.6
1s3i_A_64 - EH => SUBCLASS : 1.1.9
1s3i_A_146 - EH => SUBCLASS : 5.1.8

Loops in ArchDB95 clusters

1s3i_A_64 - EH => SUBCLASS : 1.1.13
1s3i_A_64 - EH => SUBCLASS : 1.1.14
1s3i_A_146 - EH => SUBCLASS : 6.2.1
1s3i_A_60 - HA => SUBCLASS : 2.1.1
1s3i_A_233 - HA => SUBCLASS : 2.1.1
1s3i_A_271 - HA => SUBCLASS : 2.2.2
1s3i_A_286 - HA => SUBCLASS : 4.3.1
1s3i_A_276 - HA => SUBCLASS : 5.1.8

Loops not clustered in ArchDB

1s3i_A_53 - AR
1s3i_A_240 - AR
1s3i_A_102 - EH
1s3i_A_80 - EH
1s3i_A_25 - EH
1s3i_A_2 - EH
1s3i_A_259 - HA
1s3i_A_129 - HA
1s3i_A_217 - HE
1s3i_A_118 - HE
1s3i_A_92 - HE
1s3i_A_67 - HE
1s3i_A_41 - HE
1s3i_A_10 - HE
1s3i_A_160 - HH
1s3i_A_168 - HH

2bw0 A - percentage of sequence identity: 92